Registration Dossier
Registration Dossier
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EC number: 226-242-9 | CAS number: 5333-42-6
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- weight of evidence
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- GLP compliance:
- yes (incl. QA statement)
- Reference substance (positive control):
- yes
- Remarks:
- potassium dichromate (once per month, test conducted April 7 to 8, 2010)
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 0.035 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: 95% not applicable
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 1 600 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Validity criteria fulfilled:
- yes
- Conclusions:
- 2-Octyldodecan-1-ol is not toxic to daphnia.The LC50 is > 0.035 mg/l (measured). No toxicity to daphnia within the range of water solublity.
- Executive summary:
According to data of two structurally similar substances (2-hexyldecan-1-ol (C16) and mixture of 2 -octyldodecan-1-ol and 2 -hexyl-1-tetradecanol (C20)) which show no acute toxicity to daphnia up to the limit of water solubility no toxicity to invertebrates is expected for 2 -octyldodecan-1 -ol up to the limit of water solubility.
Reference
Description of key information
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 1 600 mg/L
Additional information
There are data on acute toxicty to daphnia for three representatives of the Guerbet alcohol category.
The C12 Guerbet alcohol 2-butyloctan-1-ol show acute toxicity to daphnia in contrast to the higher alcohols 2-hexyldecan-1-ol (C16) and mixture of 2 -octyldodecan-1-ol and 2 -hexyl-1-tetradecanol (C20) which show no acute toxicity to daphnia up to the limit of water solubility. These effects can be a consequence of decreasing water solubility with increasing chain length. Thus no aquatic toxicity is considered for the Guerbet alcohols with chain lengths >= C16 with an extremely low water solubility.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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