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EC number: 500-465-4
CAS number: 160901-28-0
1 - 2.5 moles ethoxylated
The alkyl ether sulfates grouped within the AES category show similar
structural, physico-chemical, environmental and toxicological
properties. The approach of grouping different AES for the evaluation of
their effects on human health and the environment was also made by the
Danish EPA  and HERA , supporting the read across approach between
structurally related AES.
The aquatic toxicity of the alkyl ether sulfates has been evaluated in
studies on fish, invertebrates and algae as well as microorganisms. In
most of the given studies AES were tested as sodium salts. As the kation
counterpart of the AES anions is not expected to influence the
ecotoxicological profile of the substance, read-across is possible
between all comparable mixtures independent from the kation (e. g.
sodium, magnesium, ammonium, MIPA; for details see category
justification). Based on the available experimental data it is
assumed that with increasing chain lengths also the toxicity increases.
Since carbon chain lengths ≤ C10 are the main components of the AES (C9
-11, 1 -2.5EO) Na (CAS 160901 -28 -0) mixture a read-across approach
from structural comparable AES (C8-10, 1-2.5EO) mixtures was applied. To
cover the acute toxicity of aquatic invertebrates a study results from
the mixtures AES (C8-10, 1-2.5EO) Na is available. In
this study an EC50 of 91 mg a.i./L for Daphnia magna was determined. The
chronic invertebrates study was conducted with the AES (C8-10, 1-2.5EO)
NH4 (CAS 160901-28-0) mixture. Based on reproduction a NOEC of 5.3 mg
a.i./L for Daphnia magna was found. The algae endpoint was covered by a
read-across approach from AES (C8-10, 1-2.5EO) NH4 (CAS 160901-28-0). In
this study a NOEC value of 31.3 mg a. i /L was reported and the
corresponding EC50 value was assumed to be > 100 mg a.i./L.
To cover the acute toxicity on fish a read-across approach from AES
(12-14, 1-2.5EO) Na (CAS 68891-38-3) was performed as a worst case
scenario.The LC50 value determined in this read-across study was
7.1 mg a.i./L for fish.
 Danish EPA - Environmental and Health Assessment of Substances in
Household Detergents and Cosmetic Detergent Products (2001).
Environmental Project No. 615, pp. 24-28
 HERA - Human & Environmental Risk Assessment on ingredients of
European household cleaning products (2004).Alcohol Ethoxysulphates
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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