Registration Dossier
Registration Dossier
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EC number: 445-790-1 | CAS number: 404362-22-7
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The effect of the test material on the respiration of activated sewage sludge gave a 3-Hour EC50 of 70 mg/L. The No Observed Effect Concentration (NOEC) after 3 hours exposure was 10 mg/L.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 70 mg/L
- EC10 or NOEC for microorganisms:
- 10 mg/L
Additional information
A study was performed to assess the effect of the test material on the respiration of activated sewage sludge. The method followed that described in the OECD TG 209.
Following a preliminary range-finding test, activated sewage sludge was exposed to an aqueous dispersion of the test material at concentrations of 10, 32, 100, 320 and 1000 mg/L for a period of 3 hours at 21°C with the addition of a synthetic sewage as a respiratory substrate. The rate of respiration was determined after 30 minutes and 3 hours contact time and compared to data for the control and a reference material, 3,5-dichlorophenol.
The effect of the test material on the respiration of activated sewage sludge gave a 3-Hour EC50 of 70 mg/L. The No Observed Effect Concentration (NOEC) after 3 hours exposure was 10 mg/L.
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