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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
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Diss Factsheets
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EC number: 906-089-0 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
In a 48-h toxicity study according to OECD 201 and in compliance with GLP, exponentially growing green algae (Raphidocelis subcapitata) were exposed to individually prepared WSF at loading rates of 0.1, 0.32, 1.0, 3.2 and 10 mg/L. In the range finder it was seen that the 0.1 mg/l dose level decreased to LOD values at 48 hours. The 10 mg/l WAF (measured 6.2 mg/l) dose level decreased to 2% (0.132 mg/l) after 72 hours. Such measured values would (partly) lead to effect values based on (half of ) LOD which is not considered related to the toxicity of the substance. Therefore a 48h exposure was used as this is given as a possibility in OECD TG 201. The exponential growth rated was maintained and the replication factor was 72 (>16). Exposure concentrations were verified by a validated method: at the start of the test, measured concentrations were 0.071, 0.16, 0.63, 2.1 and 4.6 mg/L and these concentrations decreased to concentrations below the LOD and 8.3% of initial. Effect parameters were therefore based on arithmetic mean concentrations, calculated to be respectively 0.041, 0.096, 0.35, 1.2 and 2.8 mg/L. The 48h-ErC50 was 2.0 mg/L (95% CI 1.7 - 2.2 mg/L); the ErC10 was 0.38 mg/L (95% CI 0.24 - 0.52 mg/L) and the NOECr was 0.096 mg/L. The study is considered to be reliable without restrictions.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 2 mg/L
- EC10 or NOEC for freshwater algae:
- 0.38 mg/L
Additional information
To limit the dissipation of the test material especially in the 48-72h period, the test period was shortened to 48 hours (as described in OECD TG 201). Unlimited, exponential growth during the test was maintained and the minimum multiplication factor of 16 was still reached.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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