Registration Dossier
Registration Dossier
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EC number: 234-909-0 | CAS number: 12039-88-2
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation: in vivo (non-LLNA)
- Type of information:
- read-across based on grouping of substances (category approach)
- Adequacy of study:
- weight of evidence
- Justification for type of information:
- See attached report in section 13.
Data source
Materials and methods
Test material
- Reference substance name:
- Tungsten disilicide
- EC Number:
- 234-909-0
- EC Name:
- Tungsten disilicide
- Cas Number:
- 12039-88-2
- Molecular formula:
- Si2W
- IUPAC Name:
- Tungsten disilicide
- Test material form:
- solid: particulate/powder
Constituent 1
Results and discussion
In vivo (non-LLNA)
Resultsopen allclose all
- Reading:
- 1st reading
- Hours after challenge:
- 24
- Group:
- test chemical
- Dose level:
- not possible to specify
- No. with + reactions:
- 0
- Total no. in group:
- 10
- Reading:
- 2nd reading
- Hours after challenge:
- 48
- Group:
- test chemical
- Dose level:
- not possible to specify
- No. with + reactions:
- 0
- Total no. in group:
- 10
- Reading:
- other: negative control
- Hours after challenge:
- 24
- Group:
- negative control
- Dose level:
- not possible to spcify
- Remarks on result:
- no indication of skin sensitisation
- Reading:
- other: positive control
- Hours after challenge:
- 24
- Group:
- positive control
- Dose level:
- not possible to specify
- Remarks on result:
- other: not specified
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- None of the tungsten substances in the category, tested for skin sensitization, produced evidence of skin sensitization.
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