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EC number: 294-585-1 | CAS number: 91744-23-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- GLP compliance:
- yes (incl. QA statement)
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- other: effluent of a domestic sewage plant
- Details on inoculum:
- - Source of inoculum/activated sludge: domestic sewage plant (Taunusstein-Bleidenstadt, Germany)
- Laboratory culture: no
- Storage conditions: under aerobic conditions
- Storage length: not mentioned
- Preparation of inoculum for exposure: A mixture of 103.4 g soil was suspended in 1000 mL drinking-water and shaken at a laboratory shaker for approx. 30 min. filtration (paper filter), the first 200 mL were rejected
- Pretreatment: not mentioned
- Concentration of sludge: not mentioned
- Initial cell/biomass concentration: not mentioned
- Water filtered: not mentioned - Duration of test (contact time):
- 28 d
- Initial conc.:
- > 4 - < 5 mg/L
- Based on:
- COD
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST CONDITIONS
- Composition of medium: Nutrient mineral solutions
- Additional substrate: none
- Solubilising agent (type and concentration if used): dichloromethane, evaporated before testing
- Test temperature: mean value = 20.03 °C
- pH: not measured
- pH adjusted: not applicable
- Aeration of dilution water: not specified
- Suspended solids concentration: not mentioned
- Continuous darkness: not mentioned
- Other: none
TEST SYSTEM
- Culturing apparatus: 290 mL glass bottles with glass stoppers
- Number of culture flasks/concentration: 2 flask for t0; 7, 14, 21 days 3 flasks; and after 28 days 4 flasks
- Method used to create aerobic conditions: not mentioned
- Method used to create anaerobic conditions: not applicable
- Measuring equipment: oxygen electrode (WTW)
- Details of trap for CO2: not applicable
- Other: none
SAMPLING
- Sampling frequency: on days 0, 7, 14, 21 and 28
- Sampling method: not mentioned
- Sample storage before analysis: not mentioned
- Other: none
CONTROL AND BLANK SYSTEM
- Inoculum blank: yes (vessels with inoculum without test substance)
- Abiotic sterile control: not performed
- Toxicity control: not performed
- Other: none
STATISTICAL METHODS: no statistics performed - Reference substance:
- benzoic acid, sodium salt
- Preliminary study:
- not performed
- Test performance:
- The BOD bottles were filled by means of a lift tube and were closed without gas-bubbles inside. The number of bottles were chosen in such a way that only one oxygen measurement after 0, 7, 14, 21 and 28 days / bottle and batch (parallels) had to be performed.
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 68
- Sampling time:
- 28 d
- Results with reference substance:
- Benzoic acid, sodium salt was degraded to 76 % after 28 d.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable, but failing 10-day window
- Conclusions:
- The test substance is readily biodegradable (68 % degradation in 28 days) but fails the 10-day-window criterion.
- Executive summary:
The test substance (CAS 91744-38-6, Glycerides, C16-18 mono-, di- and tri-, hydrogenated, citrates, potassium salts) was tested for ready biodegradability according to OECD Guideline 301D (Closed Bottle Test) under GLP following the O2 consumption over a period of 28 days. The substances was tested at an initial concentration of >4 - < 5 mg/L COD. Effluent of a domestic sewage plant was used as inoculum and benzoic acid, sodium salt served as reference substance. Oxygen measurements were performed at Days 0, 7, 14, 21, and 28. Benzoic acid, sodium salt was degraded to 76 % after 28 d whereas 68 % degradation could be observed for the test substance. The test substance was evaluated to be readily biodegradable, however, the 10-day-window criterion was not met.
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- Read-across to K1 study therefore K2 is the highest score that can be assigned
- Justification for type of information:
- Please see the read-across report attached to section 13 of this dossier.
- Reason / purpose for cross-reference:
- read-across source
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- other: effluent of a domestic sewage plant
- Details on inoculum:
- - Source of inoculum/activated sludge: domestic sewage plant (Taunusstein-Bleidenstadt, Germany)
- Laboratory culture: no
- Storage conditions: under aerobic conditions
- Storage length: not mentioned
- Preparation of inoculum for exposure: A mixture of 103.4 g soil was suspended in 1000 mL drinking-water and shaken at a laboratory shaker for approx. 30 min. filtration (paper filter), the first 200 mL were rejected
- Pretreatment: not mentioned
- Concentration of sludge: not mentioned
- Initial cell/biomass concentration: not mentioned
- Water filtered: not mentioned - Duration of test (contact time):
- 28 d
- Initial conc.:
- > 4 - < 5 mg/L
- Based on:
- COD
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST CONDITIONS
- Composition of medium: Nutrient mineral solutions
- Additional substrate: none
- Solubilising agent (type and concentration if used): dichloromethane, evaporated before testing
- Test temperature: mean value = 20.03 °C
- pH: not measured
- pH adjusted: not applicable
- Aeration of dilution water: not specified
- Suspended solids concentration: not mentioned
- Continuous darkness: not mentioned
- Other: none
TEST SYSTEM
- Culturing apparatus: 290 mL glass bottles with glass stoppers
- Number of culture flasks/concentration: 2 flask for t0; 7, 14, 21 days 3 flasks; and after 28 days 4 flasks
- Method used to create aerobic conditions: not mentioned
- Method used to create anaerobic conditions: not applicable
- Measuring equipment: oxygen electrode (WTW)
- Details of trap for CO2: not applicable
- Other: none
SAMPLING
- Sampling frequency: on days 0, 7, 14, 21 and 28
- Sampling method: not mentioned
- Sample storage before analysis: not mentioned
- Other: none
CONTROL AND BLANK SYSTEM
- Inoculum blank: yes (vessels with inoculum without test substance)
- Abiotic sterile control: not performed
- Toxicity control: not performed
- Other: none
STATISTICAL METHODS: no statistics performed - Reference substance:
- benzoic acid, sodium salt
- Preliminary study:
- not performed
- Test performance:
- The BOD bottles were filled by means of a lift tube and were closed without gas-bubbles inside. The number of bottles were chosen in such a way that only one oxygen measurement after 0, 7, 14, 21 and 28 days / bottle and batch (parallels) had to be performed.
- Parameter:
- % degradation (O2 consumption)
- Value:
- 68
- Sampling time:
- 28 d
- Results with reference substance:
- Benzoic acid, sodium salt was degraded to 76 % after 28 d.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable, but failing 10-day window
- Conclusions:
- The test substance is readily biodegradable (68 % degradation in 28 days) but fails the 10-day-window criterion.
- Executive summary:
The test substance (CAS 91744-38-6, Glycerides, C16-18 mono-, di- and tri-, hydrogenated, citrates, potassium salts) was tested for ready biodegradability according to OECD Guideline 301D (Closed Bottle Test) under GLP following the O2 consumption over a period of 28 days. The substances was tested at an initial concentration of >4 - < 5 mg/L COD. Effluent of a domestic sewage plant was used as inoculum and benzoic acid, sodium salt served as reference substance. Oxygen measurements were performed at Days 0, 7, 14, 21, and 28. Benzoic acid, sodium salt was degraded to 76 % after 28 d whereas 68 % degradation could be observed for the test substance. The test substance was evaluated to be readily biodegradable, however, the 10-day-window criterion was not met.
Referenceopen allclose all
Table: Degradation kinetic
days | % degradation of test substance | % degradation of reference substance |
0 | 0 | 0 |
7 | 28 | 70 |
14 | 39 | 75 |
21 | 62 | 77 |
28 | 68 | 76 |
Table: Degradation kinetic
days | % degradation of test substance | % degradation of reference substance |
0 | 0 | 0 |
7 | 28 | 70 |
14 | 39 | 75 |
21 | 62 | 77 |
28 | 68 | 76 |
Description of key information
The test substance (CAS 91744-38-6, Glycerides, C16-18 mono-, di- and tri-, hydrogenated, citrates, potassium salts) is readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
- Type of water:
- freshwater
Additional information
The test substance (CAS 91744-38-6, Glycerides, C16-18 mono-, di- and tri-, hydrogenated, citrates, potassium salts) was tested for ready biodegradability according to OECD Guideline 301D (Closed Bottle Test) under GLP following the O2 consumption over a period of 28 days. The substance was tested at an initial concentration of >4 to < 5 mg/L COD. Effluent of a domestic sewage plant was used as inoculum and benzoic acid, sodium salt served as reference substance. Oxygen measurements were performed at Days 0, 7, 14, 21, and 28. Benzoic acid, sodium salt was degraded to 76 % after 28 d whereas 68 % degradation could be observed for the test substance. The test substance was evaluated to be readily biodegradable; however, the 10 -day-window criterion was not met.
According to the "Introduction to the OECD Guidelines for Testing of Chemicals - Section 3, Part 1: Principles and Strategies related to the Testing of Degradation of Organic Chemicals" ready biodegradability tests are intended for pure chemicals. "It is sometimes relevant to examine the ready biodegradability of mixtures of structurally similar chemicals like oils and surface-active substances (surfactants). As a sequential biodegradation of the individual structures is anticipated, the 10-day window should not be applied to interpret the results of test with mixtures of structurally related chemicals." Therefore, the 10-day window does not apply for the UVCB "Glycerides, C16-18 mono-, di- and tri-, hydrogenated, citrates, potassium salts" and the substance is readily biodegradable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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