4-bromobenzyl alcohol

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2018-03-06

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7220 (Boiling Point / Boiling Range)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

differential scanning calorimetry

Key result

Boiling pt.:

>= 245 - <= 260.4 °C

Atm. press.:

1 000.7 hPa

Decomposition:

no

Appearance of the sample

Before the test the appearance of the test item was white solid. After the experiments the test item was evaporated from the crucible.

Results

The evaluation of the data was performed using the software STARe. As result, a thermogram was obtained in which the heat flow of the investigated sample is given as a function of the temperature. By integrating the area under the heat flow signals, the enthalpy of the process was obtained. The DSC measurements were performed twice.

Table 1: Values of the DSC run in the first experiment

Sample weight [mg]	Total loss of Mass of the Sample (%)	Onset of effect [°C]	Endset of effect [°C]	Peak Maxium [°C]	Energy [J/g]
6.72	100.0	246.86	261.12	258.73	-298.94 (endothermic)

Table 2: Values of the DSC run in the second experiment

Sample weight [mg]	Total loss of Mass of the Sample (%)	Onset of effect [°C]	Endset of effect [°C]	Peak Maxium [°C]	Energy [J/g]
4.03	99.8	243.06	259.72	257.72	-285.67 (endothermic)

Table 3: Summary of the DSC Test of Test Item

	Experiment 1	Experiment 2	Mean
Onset of effect [°C]	246.86	243.06	244.96
Endset of effect [°C]	261.12	259.72	260.42
Energy [J/g]	-298.94	-285.67	-292.31

Using a linear heating rate of 10 °C/min the boiling point of the test item was determined to be in the range of 245.0 – 260.4 °C (518.1 – 533.6 K) at atmospheric pressure (100.07 kPa).

Conclusions:

The boiling point of the test item was determined to be in the range of 245.0 and 260.4 °C (518.1 to 533.6 K) at 1000.7 hPa.

Executive summary:

A study was peformed according to OECD TG 103, Commission Regulation (EC) No. 440/2008 method A.2. and EPA OPPTS 830.7220 in order to determine the boiling point of the test item by using the differential scanning calorimetry method (DSC). The test item was weighted into a one-way 40 µL aluminium crucible, sealed and heated in the DSC device from room temperature to 500 °C with a heating rate of 10 °C/min. As reference sample an empty crucible was used. The test was performed twice. The heat flow and any thermal events as well as the onset and the related energy were recorded and presented in a thermogram (software STARe). The boiling point of the test item was determined to be in the range of 245.0 and 260.4 °C (518.1 to 533.6 K) at a pressure of 1000.7 hPa.

Description of key information

The boiling point of the test item was determined to be in the range of 245.0 and 260.4 °C (518.1 to 533.6 K) at 1000.7 hPa.

Additional information

A study was peformed according to OECD TG 103, Commission Regulation (EC) No. 440/2008 method A.2. and EPA OPPTS 830.7220 in order to determine the boiling point of the test item by using the differential scanning calorimetry method (DSC). The test item was weighted into a one-way 40 µL aluminium crucible, sealed and heated in the DSC device from room temperature to 500 °C with a heating rate of 10 °C/min. As reference sample an empty crucible was used. The test was performed twice. The heat flow and any thermal events as well as the onset and the related energy were recorded and presented in a thermogram (software STARe). The boiling point of the test item was determined to be in the range of 245.0 and 260.4 °C (518.1 to 533.6 K) at a pressure of 1000.7 hPa (reference 4.3-1).