Registration Dossier
Registration Dossier
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EC number: 701-135-4 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Potential for aquatic / sediment bioaccumulation cannot be predicted using the substances octanol water partition coefficient (log Kow = 0.467), give it has surface active properties. The low potential for bioaccumulation has been confirmed in an OECD 305 bioaccumulation study in Fish.
The potential for the test substance to bioaccumulate in rainbow trout (Oncorhynchus mykiss) was studied by exposure to treated diet in a continuous flow-through system. After 14 days of exposure to the test substance, the mean concentration of total radioactivity in fish tissue was 11.4 µg equivalents/g. During the depuration phase, approximately 83% of the accumulated radioactivity was eliminated by Day 4 of depuration, and by Day 21 of depuration, approximately 98% radioactivity had been eliminated.
The growth corrected-lipid normalized biomagnification factor (BMFKgl) for the test substance itself was calculated to be 0.023 with a half-life of approximately 5.5 days. For the most prominent metabolite, M8, the growth corrected-lipid normalized biomagnification factor (BMFKgl) was calculated to be 0.027 with a half-life of approximately 1.05 days.
The estimated BCFs are below the bioaccumulation triggers used in EU member countries for a bioaccumulative (“B”: 2000 L/kg) or very bioaccumulative (“vB”: 5000 L/kg) substance.
Additional information
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