Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 200-888-1 | CAS number: 75-64-9
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Not readily biodegradable (according to OECD criteria). Easily eliminated from water after a lag phase of 19 days.
Key value for chemical safety assessment
Additional information
In a 28 -day MITI test (OECD 301C) tert-butylamine was not biodegradable. Calamari (1980) studied the ready biodegradability of the test substance. However, the method using respirometers did not closely follow the recommendations as stated in the OECD guideline 301 F, since the guidelines on the ready biodegradability were not implemented prior to 1981 and the guideline 301 F was not released before 1992.
The inoculum used in the study was a mixture of river mud bacteria inocula, treatment plant sludge inocula, or adapted bacteria inocula which were not further defined. According to the presented data biodegradation was not observed in a period of 12 days.
Two BASF-studies focused on BOD and DOC removal, respectively. The BOD test was performed according to national guidelines and demonstrated a very low biodegradation of the test substance after 5 days (< 0.31%). However, the test performed according to OECD guideline 302 B resulted in an easy elimination of the test substance from water after a lag phase of 19 days.
Therefore, the test substance is of not readily biodegradability in terms of OECD criteria, however, it can be easily eliminated from water due to biodegradation after an adaption phase.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
