Registration Dossier
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EC number: 202-433-2 | CAS number: 95-57-8
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 08 May - 23 Jun 1978
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I))
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Solubility and stability of the test substance in the solvent/vehicle: soluble in alcohol and ether - Oxygen conditions:
- aerobic
- Inoculum or test system:
- mixture of sewage, soil and natural water
- Details on inoculum:
- Preparation according to MITI standard procedure (Mixed inoculum from 10 sites: 4 sewage plants, 3 rivers, 1 lake and 2 bays around Japan)
Inoculum test concentration: 30 mg/L - Duration of test (contact time):
- 2 wk
- Initial conc.:
- 100 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Parameter followed for biodegradation estimation:
- test mat. analysis
- Details on study design:
- TEST SYSTEM
- Culturing apparatus: closed oxgen consumption measuring machine with 300 mL culture bottle
- Measuring equipment: Total organic carbon analyzer
CONTROL AND BLANK SYSTEM
- Inoculum blank: yes - Parameter:
- % degradation (O2 consumption)
- Value:
- 0
- Sampling time:
- 2 wk
- Parameter:
- % degradation (test mat. analysis)
- Value:
- 2.1
- Sampling time:
- 2 wk
- Interpretation of results:
- not readily biodegradable
Reference
Description of key information
not readily biodegradable: 2.1% after 28 d
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
There is one study available, which investigated the biodegradation of the test substance in water according to OECD 301C. Microorganisms were inoculated with 100 mg/L test substance in closed bottles for two weeks and oxygen consumption as well as GC/FID was followed to estimate biodegradation.
After two weeks the test substance was degraded by 2.1% based on analysis of the test substance and 0% based on O2 consumption. Therefore, it was concluded that the test substance is not readily biodegradable according to the OECD criteria.
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