Registration Dossier
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EC number: 202-947-7 | CAS number: 101-50-8
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
72 hrs aquatic toxicity study (SSS QSAR prediction model, 2016) was predicted to assess toxic effects of the test compound 4 -Aminoazobenzene-3,4'- disulfonic acid (CAS No. 101 -50 -8) and the results were predicted. The study was based on the effects of the test compound on Desmodesmus subspicatus in a static fresh water system. The predicted data suggests the effective concentration (EC50) for the test compound 4-Aminoazobenzene-3,4'-disulfonic acid (CAS No. 101 -50 -8) was estimated to be 128.468963623 mg/L on the basis of growth rate.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 128.469 mg/L
Additional information
Various predicted data for the target chemical 4-Aminoazobenzene-3,4'-disulfonic acid (CAS no. 101-50-8) were reviewed to summarize the following information:
72 hrs aquatic toxicity study (SSS QSAR prediction model, 2016) was predicted to assess toxic effects of the test compound 4 -Aminoazobenzene-3,4'- disulfonic acid (CAS No. 101 -50 -8) and the results were predicted. The study was based on the effects of the test compound on Desmodesmus subspicatus in a static fresh water system. The predicted data suggests the effective concentration (EC50) for the test compound 4-Aminoazobenzene-3,4'-disulfonic acid (CAS No. 101 -50 -8) was estimated to be 128.468963623 mg/L on the basis of growth rate.
96 hrs aquatic toxicity study (EPI suite, 2016) waspredictedto assess toxic effects of the test compound 4-Aminoazobenzene-3,4'-disulfonic acid (CAS no. 101-50-8) and the results were predicted. The study was based on the effects of the test compound on green algae in a static fresh water system. The predicted data suggests the effective concentration (EC50) for the test compound 4-Aminoazobenzene-3,4'-disulfonic acid (CAS no. 101-50-8) was estimated to be 12858.936 mg/l on the basis of growth rate.
72 hrs aquatic toxicity study (Danish (Q)SAR Database, 2016) was predicted to assess toxic effects of the test compound 4 - Aminoazobenzene-3,4'- disulfonic acid (CAS no. 101-50-8) and the results were predicted. The study was based on the effects of the test compound on Pseudokirchneriella spp. in a static fresh water system. The predicted data suggests the effective concentration (EC50) for the test compound 4-Aminoazobenzene-3,4'-disulfonic acid (CAS no. 101-50-8) was estimated to be 2749.327mg/L on the basis of growth rate.
On the basis of the above resultsof predicted data for target chemical, it can be concluded that the substance can be considered as non-toxic to aquatic organisms and thus, cannot be classified as hazardous as per the criteria of CLP regulation.
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