4,4-bis(methoxymethyl)biphenyl

Surface tension

Administrative data

Endpoint:

surface tension

Type of information:

experimental study

Adequacy of study:

key study

Study period:

Testing was conducted between 17 December 2008 and 27 January 2009.

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Study conducted in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of relevant results.

Cross-reference

Reason / purpose for cross-reference:

reference to other study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2009

Report date:

2009

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

EU Method A.5 (Surface Tension)

Deviations:

yes

Remarks:

Please see explanation in Section "Overall Remarks"

GLP compliance:

yes (incl. QA statement)

Remarks:

UK GLP standards (Schedule 1, Good Laboratory Practice Regulations 1999 (SI 1999/3106 as amended by SI 2004/0994)). Date of inspection: 21/08/2008. Date of signature: 04/03/2009.

Type of method:

other: The determination was carried out using a White Electrical Institute interfacial tension balance and a procedure based on the ISO 304 ring method.

Test material

Test material information

Constituent 1

Reference substance name:

4,4'-bis(methoxymethyl)-1,1'-biphenyl

EC Number:

700-008-0

Cas Number:

3753-18-2

Molecular formula:

C16 H18 O2

IUPAC Name:

4,4'-bis(methoxymethyl)-1,1'-biphenyl

Constituent 2

Reference substance name:

4,4-bis(methoxymethyl)-biphenyl

IUPAC Name:

4,4-bis(methoxymethyl)-biphenyl

Results and discussion

Surface tension

Surface tension:

51.5 mN/m

Temp.:

22 °C

Conc.:

26.4 mg/L

Any other information on results incl. tables

Results

Sample solution concentration

The mean peak height relating to the standard and sample solutions are shown in the following table:

Solution	MeanHeight
Standard 1.61 mg/l	5.120
Standard 1.50 mg/l	4.857
Matrix blank	6.963 x 10^-2
Sample A	8.275
Sample B	8.635
Mean sample solution concentration 2.64 x 10^-2g/l

 

Calibration factor (f)

The readings, temperatures and the corresponding calibration factors for glass double-distilled water are shown in the following table:

Reading (mN/m)	Temperature (ºC)	Literature Value (mN/m)	Calibration Factor
72.0	22.0	72.41	1.006
72.5	22.0	72.41	0.999
72.5	22.0	72.41	0.999
72.5	22.0	72.41	0.999
72.5	22.0	72.41	0.999
72.5	22.0	72.41	0.999
Mean Calibration Factor = 1.00

Sample solution readings

The readings, times and temperatures for the sample solution are shown in the following table:

Time (mins)	Reading (mN/m)	Temperature (ºC)
70	51.5	22.0
80	51.5	22.0
90	51.5	22.0
100	51.5	22.0
110	51.5	22.0

Mean reading                  51.5 mN/m
Surface tension               = reading x calibration factor
                                         = 51.5 x 1.00
                                         = 51.5 mN/m
Temperature                    22.0 ± 0.5ºC
pH of sample solution    6.7

Applicant's summary and conclusion

Conclusions:

The surface tension of a 2.64 x 10-2 g/l solution of test material has been determined to be 51.5 mN/m at 22.0 ± 0.5°C. The test material is considered not to be a surface-active material.

Executive summary:

The determination was carried out using a White Electrical Institute interfacial tension balance and a procedure based on the ISO 304 ring method. With the exception of the following deviation, the experintal procedure used complied with that specified in Method A5 Surface Tension of Council Regulation (EC) No 440/2008 of 30 May 2008.

1)        The surface tension result was not corrected using the Harkins-Jordan correction table as the correction is not applicable to the apparatus used. Once calibrated, the balance and ring assembly used in this test give a direct reading for surface tension that is within the required accuracy (± 0.5 mN/m); this is as a result of the reduced ring dimensions.

This deviation has been considered not to have affected the integrity of the study.

The surface tension of a 2.64 x 10^-2 g/l solution of test material has been determined to be 51.5 mN/m at 22.0 ± 0.5°C. The test material is considered not to be a surface-active material.