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EC number: 203-468-6
CAS number: 107-15-3
Mean erythema score after 24, 48
and 72 h (animal1/2)
Already a 1 min exposure with
ethylenediamine caused necrosis to the exposed skin.
The original BASF grading was
converted into the numerical grading according the OECD Draize system.
In a skin irritation/corrosion test, Vienna
White rabbits were exposed to ethylene diamine.Two animals were treated
for 1, 5 and 15 min using occlusive conditions. An application site of
2.5x2.5 cm was covered with the liquid test substance. After the
application time the skin was washed with Lutrol (conc.) and
Lutrol/water (1:1). The animals were observed for 14 days and skin
changes were recorded daily. Ethylene diamine is corrosive to rabbit skin.
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