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EC number: 203-468-6
CAS number: 107-15-3
Mean erythema score after 24, 48
and 72 h (animal1/2)
Already a 1 min exposure with
ethylenediamine caused necrosis to the exposed skin.
The original BASF grading was
converted into the numerical grading according the OECD Draize system.
In a skin irritation/corrosion test, Vienna White rabbits were exposed
to ethylene diamine.Two animals were treated for 1, 5 and 15 min using
occlusive conditions. An application site of 2.5x2.5 cm was covered with
the liquid test substance. After the application time the skin was
washed with Lutrol (conc.) and Lutrol/water (1:1). The animals were
observed for 14 days and skin changes were recorded daily.
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