Registration Dossier

Physical & Chemical properties

Density

Currently viewing:

Administrative data

Link to relevant study record(s)

Referenceopen allclose all

Endpoint:
relative density
Type of information:
experimental study
Adequacy of study:
key study
Study period:
August 2010
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Remarks:
Study performed according to international guidelines but not under GLP and with some lack of details.
Reason / purpose:
reference to same study
Reason / purpose:
reference to other study
Qualifier:
according to
Guideline:
OECD Guideline 109 (Density of Liquids and Solids)
Deviations:
not specified
Qualifier:
according to
Guideline:
EU Method A.3 (Relative Density)
Deviations:
not specified
GLP compliance:
no
Type of method:
oscillating densitimeter
Key result
Type:
relative density
Density:
0.844
Temp.:
20 °C
Remarks on result:
other: relative density at 20 °C in reference with water at 4 °C

The obtained value is the mean result of three determinations at 20 ± 0.5 °C :

Assay No.

Density (kg/m3)

Relative density

1

844.1

0.8441

2

844.0

0.8440

3

844.1

0.8441

Mean ± standard deviation

844.1 ± 0.1

0.8441 ± 0.0001

Relative density = density (kg/m3) / 999.975 (kg/m3) (density of water at 4°C).

The average density at 20°C ± 0.5 °C of the test item is 844 ± 1 kg/m3.

Conclusions:
The relative density at 20°C/4°C of D-LIMONENE (5989-27-5) is 0.844 ± 0.001.
Executive summary:

The relative density of D-LIMONENE has been measured according to OECD Guideline 109 and to EU Method A.3.

Using an oscillating densimeter, the relative density of the test item at 20°C in reference with water at 4°C (D20/4) was determined as 0.844 ± 0.001.

The result has been considered as reliable with restrictions because the test was performed in complinace with edicted guidelines giving scientifically valid results but some details are lacking in the report (no GLP, no report number, criteria of validity of the results not given).

Endpoint:
density
Remarks:
density
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
2005
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment
Remarks:
Documentation insufficient for assessment: no certificate of analysis of the test substance, no details on methodology
Reason / purpose:
reference to same study
Reason / purpose:
reference to other study
Principles of method if other than guideline:
Method: Density measured using Anton Paar (DMA58) densimeter
GLP compliance:
not specified
Type of method:
other: densimeter
Type:
density
Density:
0.837 g/cm³
Temp.:
298.15 K

None

Conclusions:
The density of (+)-limonene was measured to be 0.83731 g/cm3 at 298.15 K.
Executive summary:

A study was conducted to determine the density of (+)-limonene using Anton Paar (DMA58) densimeter.

The density of (+)-limonene was measured to be 0.83731 g/cm3 at 298.15 K.

Endpoint:
relative density
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
no data
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Reason / purpose:
reference to same study
Reason / purpose:
reference to other study
Principles of method if other than guideline:
Method followed unknown, data from handbook
GLP compliance:
not specified
Type of method:
other: no data
Type:
relative density
Density:
0.84
Temp.:
21 °C
Remarks on result:
other: relative density at 21 °C against water at 4 °C

None

Conclusions:
The relative density D21/4 of d-limonene is 0.8402.
Executive summary:

The relative density of d-limonene was reported in the Merck Index 2006 as 0.8402 at 21 °C against water at 4 °C.

The reliability of this result has been considered as 2 (reliable with restrictions) because ‘The Merck Index’ is cited as a reference book containing peer reviewed data in the REACH Guidance Document R.7a.

Endpoint:
relative density
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study
Justification for type of information:
D-Limonene is one of the two isomers of dipentene. Therefore, data on dipentene can be used for extrapolation to d-limonene. See read-across justification document in section 13.
Reason / purpose:
read-across source
Type:
relative density
Density:
0.84
Temp.:
20.85 °C
Remarks on result:
other: relative density against water at 4 °C

None

Conclusions:
The relative density D20.85/4 of dl-limonene is 0.8402.
Executive summary:

The relative density of dl-limonene was reported in the Merck Index 2006 as 0.8402 at 20.85 °C against water at 4 °C.

The reliability of this result has been considered as 2 (reliable with restrictions) because ‘The Merck Index’ is cited as a reference book containing peer reviewed data in the REACH Guidance Document R.7a.

Endpoint:
relative density
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study
Justification for type of information:
L-Limonene is the S-isomer of d-limonene. Therefore, data on l-limonene can be used for extrapolation to d-limonene. See read-across justification document in section 13.
Reason / purpose:
read-across source
Principles of method if other than guideline:
Method followed unknown, data from handbook
Type:
relative density
Density:
0.841
Temp.:
20.5 °C
Remarks on result:
other: relative density against water at 4 °C

None

Conclusions:
The relative density D20.5/4 of l-limonene is 0.8407.
Executive summary:

The relative density of l-limonene was reported in The Merck Index 2006 as 0.8407 at 20.5 °C against water at 4 °C.

The reliability of this result has been considered as 2 (reliable with restrictions) because ‘The Merck Index’ is cited as a reference book containing peer reviewed data in the REACH Guidance Document R.7a.

Description of key information

The relative density of D-LIMONENE at 20 °C (D20/4) is 0.844 ± 0.001.

Key value for chemical safety assessment

Relative density at 20C:
0.844

Additional information

The relative density of D-LIMONENE at 20°C in reference with water at 4°C was determined in a study performed according to OECD guideline 109 and EU method A3 using an oscillating densimeter. The value was considered with a reliability of 2 (reliable with restrictions) because the result is scientifically acceptable but not obtained under GLP and some details were lacking in the report. However the relative density is valid as key value and supported by several studies measuring density or relative density of d-, l- or dl-limonene at different temperatures.