Registration Dossier

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

Abiotic degradation:

The tropospheric half-life of 2-Pyrrolidone was estimated based on a calculation with the scientifically accepted EPI-Win software tool of US-EPA (AOP-Win, v.1.92). In the atmosphere 2-pyrrolidone is expected to be indirectly photodegraded with a half life of ca. 10.8 hours. The calculation indicates a rapid degradation of 2-pyrrolidone when potentially entering the atmosphere. It is not to be expected that 2-pyrrolidone will accumulate in the air or be transported in the gaseous phase over long distances. Hence, air will not be an environmental compartment of concern for the compound. Hydrolysis is not expected under environmental conditions.


The study results regarding ready biodegradation are derived from the analogue 1-methyl-2-pyrrolidone (NMP, CAS 872-50-4) due to the fact that no studies were available for 2-pyrrolidone (CAS 616-45-5). Such cross-reading between these components is confirmed by the results for inherent biodegradability. Here for both substances the biodegradation showed the same result.

In different screening test the analogue substance to 2-pyrrolidone (1-methyl-2pyrrolidone) showed ready biodegradability. In experiments for inherent biodegradability it was found that both substances, 2-pyrrolidone as well as 1-methyl-2-pyrrolidone, are easily eliminated from water. The biodegradation level in soil was found to be higher than 90 %.