Registration Dossier

Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Administrative data

Endpoint:
bioaccumulation: aquatic / sediment
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: no information available whether the calculation model is validated for the substance under investigation

Data source

Reference
Reference Type:
other: unpublished calculation
Title:
Unnamed
Year:
2007

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
The bioconcentration factor of styrene oxide was calculated using EPIWIN v3.20, BCFWIN v2.17.
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test conditions

Details on estimation of bioconcentration:
BASIS FOR CALCULATION OF BCF
- Estimation software: EPIWIN v3.20, BCFWIN v2.17
- Result based on measured log Pow of: 1.61

Results and discussion

Bioaccumulation factor
Type:
BCF
Value:
3.5

Any other information on results incl. tables

The bioconcentration factor of styrene oxide was calculated using EPIWIN v3.20, BCFWIN v2.17. The calculation yielded a BCF=3.5 taking into account the measured log Kow=1.61. The result indicates a very low potential for bioaccumulation. Due to missing information about the applicability of the calculation model in respect to the substance under investigation the result and the conclusion thereof should be treated with care.

Applicant's summary and conclusion

Validity criteria fulfilled:
not applicable
Conclusions:
The bioconcentration factor of styrene oxide was calculated using EPIWIN v3.20, BCFWIN v2.17. The calculation yielded a BCF=3.5 taking into account the measured log Kow=1.61. The result indicates a very low potential for bioaccumulation. Due to missing information about the applicability of the calculation model in respect to the substance under investigation the result and the conclusion thereof should be treated with care.