Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (sensitising)
Additional information:

The substance is officially classified as R42/43, so there is no need to perform new test on skin sensitization according to column 2 in REACH Annex VII.


Migrated from Short description of key information:
Maleic anhydride is a skin sensitizer.

Respiratory sensitisation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (sensitising)
Additional information:
Maleic anhydride is officially classified as R42/43, so there is no need to performed new test on skin sensitization according to column 2 in Annex VII REACH regulation.

Migrated from Short description of key information:
Maleic anhydride is a respiratory sensitizer.

Justification for classification or non-classification

Maleic anhydride is officially classified as R42/43 according to Directive 67/548/EEC.