Registration Dossier

Administrative data

Key value for chemical safety assessment

Genetic toxicity in vitro

Description of key information

Bacterial Reverse Mutation data

 

Protocol
[Klimisch rating]

Strains tested

Positive and negative controls

Maximum tested dose

Result with and without metabolic activation

Reference

Data for TEGBE

OECD 471
[2]

TA 97, 98, 100, 1535, 1537

Yes

5mg/plate

Without: Negative
With: Negative (rat S9)

BASF (1989)

Genetic toxicity in vivo

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (negative)

Additional information

Based on data from category members and supported by reliable QSARs plus limited data on the subtance itself, this substance is expected to produce negative results from standard genotoxicity/mutagenicity assays. Note that further testing is underway on this substance to provide additional data to support this conclusion.

Justification for classification or non-classification

From the available data, there is no indication of the substance having genotoxic or mutagenic properties, therefore classification is not warranted.