Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: - | CAS number: -
Manufacture, use & exposure
Uses at industrial sites
Documentsopen allclose all
Uses at industrial sites
- Registration/ Notification status for the use:
- use as intermediate registered according to REACH Article 10; total tonnage manufactured/imported >=10tonnes/year per registrant
Contributing activity / technique for the environment
- Name of activity / technique:
- Purification of CAE with activated carbon.
- Environmental release category (ERC):
- ERC4: Use of non-reactive processing aid at industrial site (no inclusion into or onto article)
Contributing activity / technique for workersopen allclose all
- Name of activity / technique:
- Charging the CAE into the reactor
- Process category (PROC):
- PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
- Name of activity / technique:
- Filling the drums with CAET
- Process category (PROC):
- PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
- Name of activity / technique:
- Removal of the activated carbon impregnated of CAE from the filter
- Process category (PROC):
- PROC 8a: Transfer of substance or mixture (charging and discharging) at non-dedicated facilities
- Product category used:
- PC 29: Pharmaceuticals
- Substance supplied to that use in form of:
- as such
- Related assessment:
- use assessed in an own CSR
Contributing scenario for the environment (related to workers activities)
Conditions of use for the environment
Amounts used, frequency and duration of use (or from service life)
Conditions and measures related to Biological Sewage Treatment Plant
- Biological Sewage Treatment Plant (STP):
- site specific and municipal biological STP
- Application of site specific biological STP sludge on agricultural soil:
- yes
Conditions and measures related to external treatment of waste (including article waste)
- Particular considerations on the waste treatment operations:
- no
Other conditions affecting environmental exposure
- Place of use:
- indoor
Other conditions of use
Releases to waste and the environment
Release to the environment
ReleaseEnvirRepopen allclose all
- Release from the site to::
- wastewater
- Release estimation method:
- estimated release factor
- Release from the site to::
- ambient air
- Release estimation method:
- estimated release factor
- Release from the site to::
- non-agricultural soil
- Release estimation method:
- estimated release factor
Exposure of the environment
PECopen allclose all
- Exposed compartment:
- freshwater
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sediment (freshwater)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- marine water
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sediment (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sewage treatment plant
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- air
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- agricultural soil
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (freshwater)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- top predators' prey (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (terrestrial)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
Exposure of humans via the environment
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
ContribScenWorkersRepopen allclose all
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
- Physical form of the used product:
- liquid, including paste/slurry/suspension
Amounts used (or contained in articles), frequency and duration of use/exposure
Technical and organisational conditions and measures
TechCondRepopen allclose all
Conditions and measures related to personal protection, hygiene and health evaluation
Effectiveness
- Route affected:
- dermal
Other conditions affecting workers exposure
- Place of use:
- indoor
Other conditions of use
Exposure of workers
ExpEstopen allclose all
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- Stoffenmanager
- Type of exposure:
- inhalation (external) short-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- Stoffenmanager
- Type of exposure:
- dermal (external) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers
- Type of exposure:
- dermal (external) local concentration on skin
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
- Physical form of the used product:
- liquid, including paste/slurry/suspension
Amounts used (or contained in articles), frequency and duration of use/exposure
Technical and organisational conditions and measures
TechCondRepopen allclose all
Conditions and measures related to personal protection, hygiene and health evaluation
Effectiveness
- Route affected:
- dermal
Other conditions affecting workers exposure
- Place of use:
- indoor
Other conditions of use
Exposure of workers
ExpEstopen allclose all
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- Stoffenmanager
- Type of exposure:
- inhalation (external) short-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- Stoffenmanager
- Type of exposure:
- dermal (external) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers
- Type of exposure:
- dermal (external) local concentration on skin
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
- Physical form of the used product:
- solid (unspecified form)
Amounts used (or contained in articles), frequency and duration of use/exposure
Technical and organisational conditions and measures
TechCondRepopen allclose all
Effectiveness
- Route affected:
- inhalation
Conditions and measures related to personal protection, hygiene and health evaluation
PPERepopen allclose all
Other conditions affecting workers exposure
- Place of use:
- indoor
Other conditions of use
Exposure of workers
ExpEstopen allclose all
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers
- Type of exposure:
- inhalation (external) short-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers
- Type of exposure:
- dermal (external) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers
- Type of exposure:
- dermal (external) local concentration on skin
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers
Uses at industrial sites
- Registration/ Notification status for the use:
- use as intermediate registered according to REACH Article 10; total tonnage manufactured/imported >=10tonnes/year per registrant
Contributing activity / technique for the environment
- Name of activity / technique:
- Use as intermediate for synthesis of pharmaceutical substance
- Environmental release category (ERC):
- ERC6a: Use of intermediate
Contributing activity / technique for workersopen allclose all
- Name of activity / technique:
- Sampling of CAET
- Process category (PROC):
- PROC 9: Transfer of substance or mixture into small containers (dedicated filling line, including weighing)
- Name of activity / technique:
- Analysis of CAET
- Process category (PROC):
- PROC 15: Use as laboratory reagent
- Name of activity / technique:
- Opening of drums bungs before charging the drums in the oven.
- Process category (PROC):
- PROC 4: Chemical production where opportunity for exposure arises
- Name of activity / technique:
- Transfer of the CAET in the saponification reactor
- Process category (PROC):
- PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
- Sector of end use:
- SU 0: Other:
- Substance supplied to that use in form of:
- as such
- Related assessment:
- use assessed in an own CSR
Contributing scenario for the environment (related to workers activities)
Conditions of use for the environment
Amounts used, frequency and duration of use (or from service life)
Technical and organisational conditions and measures
Other technical and organisational conditions
EffectivenessRepopen allclose all
- Route affected:
- water
- Route affected:
- air
Conditions and measures related to Biological Sewage Treatment Plant
- Biological Sewage Treatment Plant (STP):
- no
Conditions and measures related to external treatment of waste (including article waste)
- Particular considerations on the waste treatment operations:
- no
Other conditions affecting environmental exposure
- Place of use:
- indoor
Releases to waste and the environment
Release to the environment
ReleaseEnvirRepopen allclose all
- Release from the site to::
- surface water
- Release estimation method:
- estimated release factor
- Release from the site to::
- ambient air
- Release estimation method:
- estimated release factor
- Release from the site to::
- non-agricultural soil
- Release estimation method:
- estimated release factor
- Remarks:
- 0
Exposure of the environment
PECopen allclose all
- Exposed compartment:
- freshwater
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sediment (freshwater)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- marine water
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sediment (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- sewage treatment plant
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- air
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- agricultural soil
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (freshwater)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- top predators' prey (marine water)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
- Exposed compartment:
- predators' prey (terrestrial)
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
Exposure of humans via the environment
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- EUSES
ContribScenWorkersRepopen allclose all
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
- Physical form of the used product:
- liquid, including paste/slurry/suspension
Amounts used (or contained in articles), frequency and duration of use/exposure
Technical and organisational conditions and measures
TechCondRepopen allclose all
Conditions and measures related to personal protection, hygiene and health evaluation
Effectiveness
- Route affected:
- dermal
Other conditions affecting workers exposure
- Place of use:
- indoor
Other conditions of use
Exposure of workers
ExpEstopen allclose all
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- Stoffenmanager
- Type of exposure:
- inhalation (external) short-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- Stoffenmanager
- Type of exposure:
- dermal (external) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers
- Type of exposure:
- dermal (external) local concentration on skin
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
- Physical form of the used product:
- liquid, including paste/slurry/suspension
Amounts used (or contained in articles), frequency and duration of use/exposure
Technical and organisational conditions and measures
TechCondRepopen allclose all
Effectiveness
- Route affected:
- inhalation
Conditions and measures related to personal protection, hygiene and health evaluation
Effectiveness
- Route affected:
- dermal
Other conditions affecting workers exposure
- Place of use:
- indoor
Other conditions of use
Exposure of workers
ExpEstopen allclose all
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- Stoffenmanager
- Type of exposure:
- inhalation (external) short-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- Stoffenmanager
- Type of exposure:
- dermal (external) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers
- Type of exposure:
- dermal (external) local concentration on skin
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
- Physical form of the used product:
- liquid, including paste/slurry/suspension
Amounts used (or contained in articles), frequency and duration of use/exposure
Technical and organisational conditions and measures
TechCondRepopen allclose all
Conditions and measures related to personal protection, hygiene and health evaluation
Effectiveness
- Route affected:
- dermal
Other conditions affecting workers exposure
- Place of use:
- indoor
Other conditions of use
Exposure of workers
ExpEstopen allclose all
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- Stoffenmanager
- Type of exposure:
- inhalation (external) short-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- Stoffenmanager
- Type of exposure:
- dermal (external) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers
Contributing scenario for the workers
Conditions of use for workers
Product (article) characteristics
- Physical form of the used product:
- liquid, including paste/slurry/suspension
Amounts used (or contained in articles), frequency and duration of use/exposure
Technical and organisational conditions and measures
TechCondRepopen allclose all
Effectiveness
- Route affected:
- inhalation
Conditions and measures related to personal protection, hygiene and health evaluation
PPERepopen allclose all
Other conditions affecting workers exposure
- Place of use:
- indoor
Other conditions of use
Exposure of workers
ExpEstopen allclose all
- Type of exposure:
- inhalation (external) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers
- Type of exposure:
- dermal (external) long-term exposure
- Exposure estimation method:
- exposure estimation tool
- Exposure estimation tool name:
- ECETOC TRA workers
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
