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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Description of key information

EC50 48h Daphnia magna > 113 mg/l

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
113 mg/L

Additional information

No specific tests on the registering substance have been performed, but the substance is part of the Stilbene Fluorescent Whitening Agent category, group 3, in which all members share the common organic functional group dihydroxyethylamino derivative, with different sulphonation degrees: acid form (CAS 4404-43-7), disulphonated sodium salt (CAS 4193-55-9), disulphonated sodium/potassium form (CAS 70942-01-7) tetrasulphonated (CAS 16470-24-9) and hexa sulphonated (CAS 68971 49-3). Within this group the substance with the highest experimental solubility, therefore the most representative for environmental testing is the tetrasulphonated CAS 16470 -24 -9, for which the summary of the studies are reported here:

Acute toxicity for Daphnia magna was evaluated on CAS 16470-24-9 in a 48 hours screening test, according to the OECD guideline 202. A single dose was administrated at 100 mg/l (limit test) with no effect.

The result was confirmed two supporting studies, one performed at just 24h (Ciba-Geigy 1988) and the other one at 48 but just the summary is available (Solvias AG, 1999), with no effect up to 1000 mg/l

Also for the disulphonated sodium salt and sodium /potassium salts the studies are reported with no effect at the highest tested concentration (respectively 100 and 1000 mg/l).

For all five substances a purity of about 80% is indicated, with about 10% of inorganic impurities (sodium or potassium inorganic salts) and about 10% of organic impurities, mainly derivatives with a monohydroxyethylamino ot trihydroxyethylamino substitution instead than di-substitution. The same relationship that is set out for the substances of the group 3 appies also to their impurities.

For the whole category short term toxicity to aquatic invertebrate has been tested for nine over 14 substances and none of the existing tests arised any concern for aquatic invertebrate toxicity

As a consequence it can be concluded that no short term toxicity to aquatic invertebrate is expected also for CAS 68971-49-3. The result of the key study for CAS 16470-24-9 is taken as a refence for risk assessment