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Diss Factsheets
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EC number: 209-711-2 | CAS number: 591-27-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 9 September 2013 to 10 December 2013
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- Experimental test result performed using standard test guidelines
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Deviations:
- no
- Principles of method if other than guideline:
- The melting point of 3-aminophenol is determined.
- GLP compliance:
- not specified
- Type of method:
- capillary method
- Specific details on test material used for the study:
- - Name of test material: 3-aminophenol
- IUPAC name: 1-Hydroxy-3-amino-benzene
- Molecular weight: 109.127 g/mole
- Molecular formula: C6H7NO
- Smiles: c1c(cccc1O)N
- InChI: 1S/C6H7NO/c7-5-2-1-3-6(8)4-5/h1-4,8H,7H2
- Substance type: Organic
- Physical state: Solid Crystalline (white) - Key result
- Melting / freezing pt.:
- >= 116 - <= 122 °C
- Decomposition:
- no
- Remarks on result:
- other: no other details mentioned
- Conclusions:
- The test item melted in the range of 116 °C to 122 °C (389 K to 395 K).
- Executive summary:
The purpose of this study was to evaluate the melting point or melting range of the test item by the capillary method using an electronically controlled heating system, according to the A1 method and the OECD 102 guideline, and following the GLP. The determination of the melting point was performed by visual judgement using the capillary method. In the preliminary test the test item started melting at 117 °C. The test item showed five stages of melting. The melting started at 116 °C. At 122 °C the last stage of melting was reached.
Hence, the melting point was found in the range of 116 °C to 122 °C (389 K to 395 K).
Reference
The determination of the melting point was performed by visual judgement using the capillary method. In the preliminary test the test item started melting at 117 °C. The test item showed five stages of melting. The melting started at 116 °C. At 122 °C the last stage of melting was reached.
Description of key information
The test item melted in the range of 116 °C to 122 °C (389 K to 395 K).
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- 122 °C
Additional information
The purpose of this study was to evaluate the melting point or melting range of the test item by the capillary method using an electronically controlled heating system, according to the A1 method and the OECD 102 guideline, and following the GLP. The determination of the melting point was performed by visual judgement using the capillary method. In the preliminary test the test item started melting at 117 °C. The test item showed five stages of melting. The melting started at 116 °C. At 122 °C the last stage of melting was reached. Hence, the melting point was found in the range of 116 °C to 122 °C (389 K to 395 K).
Other supporting data from reliable handbooks, publications and authoritative databases, also supported the selected key study and
exhibited the melting point of 3-aminophenol as 123°C, 122-123°C and 122 °C respectively.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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