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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

No toxic effects in the range of water solubility

The aquatic toxicity of 4,6-bis(octylthiomethyl)-o-cresol has been extensively tested towards various organisms. The following table reflects the outcome of these tests:

Test organism

Test duration

Effect parameter

Effect value (mg/L)

Nominal/
measured

OECD guideline

Vehicle

Remarks

Brachydanio rerio

96h

LC50

>100

nominal

203

yes

No effects at the highest test concentrations

Daphnia magna

24h

LC50

Not reliable

nominal

202

yes

Calculation of EC50 was not possible

Daphnia magna

21d

NOEC

>=0.0088

measured

211

no

No effects up to the highest test concentration

Scenedesmus subspicatus

72h

LC50

>100

nominal

201

no

No effects at the highest test concentrations

 

It should be noted, that due to the low water solubility and high adsorptivity, 4,6-bis(octylthiomethyl)-o-cresol is difficult to test. In some cases water accomodated fractions of supersaturated emulsions were tested without the use of vehicles. On the other hand, some tests were performed using solvents. Therefore, the interpretation of these aquatic toxicity tests should be taken with care.

 

Nevertheless, no toxic effects of 4,6-bis(octylthiomethyl)-o-cresol were observed at the highest test substance concentrations among all tests. Therefore, the test substance is not toxic within or even well above its limit of water solubility.

 

The toxicity towards aquatic bacteria, was also tested. In a short term respiration test according to OECD guideline 209, no effects on activated sludge were detected at the highest test concentration (100 mg/L). Therefore, the inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriate low concentrations.