Registration Dossier
Registration Dossier
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EC number: 205-465-5 | CAS number: 141-17-3
Endpoint summary
Administrative data
Description of key information
Additional information
Experimental studies are available investigating the effects of
Bis(2-(2-butoxyethoxy)ethyl) adipate (CAS 141-17-3) on three different
trophic levels. All experimental studies were performed according to
internationally accepted guidelines and GLP.
Freshwater fish (Oncorhynchus mykiss) turned out to be the most
sensitive species with a LC50 (96 h) of 13 mg/L followed by aquatic
algae (Pseudokirchneriella subcapitata) with an ErC50 (72 h) of 37.6
mg/L and aquatic invertebrates (Daphnia magna) with an EC50 (48 h) of
420 mg/L. For aquatic algae the chronic effects were investigated by the
available study according to OECD 201.The EC10 (72 h) of 13.3 mg/L
determined in the available study on aquatic algae was used for the
chronic toxicity assessment. Long-term testing with aquatic
invertebrates and fish was not considered to be relevant since the
chemical safety assessment according to Annex I of Regulation (EC) No
1907/2006 does not indicate the need for further investigations of
aquatic toxicity.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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