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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
GLP compliance:
no
Type of method:
flask method
Water solubility:
6.65 g/L
Conc. based on:
test mat.
Temp.:
20 °C
pH:
1.92

Preliminary solubility result

Reference samples and extract were first measured in the range 190 / 800 nm, so as to choose the right wavelength for quantitative measurements. Since absorbance of the test solution kept the same proportions along the UV and visible spectra, preliminary test result was considered for the final result calculations. Wavelength chosen was 616.00 nm.

Test results

Reference solutions were measured in the spectrophotometer in quantitative mode, thus generating a calibration curve. Calibration curve was smooth and linear at every concentration. Considering that preliminary test resulted in an absorbance keeping the same shape like the references, its value was considered for the 24 hours’ measurement. Adjusting concentrations in proportion to the real weights the following results were obtained:

test 1 (24 h) 60.51 g/l
test 2 (48 h) 60.96 g/l
test 3 (96 h) 60.49 g/l
average solubility 60.65 g/l
standard deviation 0.27
pH mother solution 4.32
Conclusions:
Water solubility is 60.65 g/l at 20 °C and pH 4.32
Executive summary:

Method

Water solubility determined by flask method according to OECD guideline 105.

Results

Average water solubility ar 24, 48 and 96 h is 60.65 g/l at 20 °C and pH 4.32.

Description of key information

60.65 g/L

Key value for chemical safety assessment

Water solubility:
6.65 g/L
at the temperature of:
25 °C

Additional information