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Physical & Chemical properties

Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
November 3, 2016
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with generally accepted scientific standards and described in sufficient detail
Principles of method if other than guideline:
Based on internal method SOP-STR 071 (Hydro 2000S) corresponding to the laser light scattering procedure.
The particle size distribution was analysed using the Mastersizer 2000 tool, which uses the technique of laser diffraction to measure the size of particles. It measures the intensity of light scattered as a laser beam passes through a dispersed particulate sample. This data is then analysed to calculate the size of the particles that created the scattering pattern.
GLP compliance:
no
Type of method:
Laser scattering/diffraction
Type of distribution:
volumetric distribution
Percentile:
D10
Mean:
10.232 µm
Remarks on result:
other: after 2 minutes ultrasonic treatment
Percentile:
D50
Mean:
38.366 µm
Remarks on result:
other: after 2 minutes ultrasonic treatment
Percentile:
D90
Mean:
80.396 µm
Remarks on result:
other: after 2 minutes ultrasonic treatment
Conclusions:
D10 = 10.232 µm
D50 = 38.366 µm
D90 = 80.396 µm
Executive summary:

Method

The particle size distribution was analysed using the Mastersizer 2000 tool, which uses the technique of laser diffraction to measure the size of particles. This is obtained by measuring the intensity of light scattered as a laser beam passes through a dispersed particulate sample. This data is then analysed to calculate the size of the particles that created the scattering pattern.

Result

After 2 minutes of ultrasonic treatment:

D10 = 10.232 µm

D50 = 38.366 µm

D90 = 80.396 µm

Description of key information

D10 = 10.232 µm

D50 = 38.366 µm

D90 = 80.396 µm

Additional information