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EC number: 848-720-1 | CAS number: 1616494-50-8
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 09 March 2020 - 22 July 2020
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- no
- GLP compliance:
- yes
- Test organisms (species):
- Daphnia magna
- Duration:
- 48 h
- Dose descriptor:
- EL50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Validity criteria fulfilled:
- yes
- Conclusions:
- The acute toxicity of the test item to the freshwater invertebrate Daphnia magna has been investigated and gave a 48-Hour EL50 value of greater than100 mg/L loading rate WAF. The NOEL rate was 100 mg/L loading rate WAF.
- Executive summary:
The acute toxicity of the test item to the freshwater invertebrate Daphnia magna has been investigated and gave a 48-Hour EL50 value of greater than100 mg/L loading rate WAF. The NOEL rate was 100 mg/L loading rate WAF.
Reference
Chemical analysis of the freshly prepared 100 mg/L loading rate WAF preparation at 0 hours, and of the corresponding aged preparation at 24 hours, showed measured test concentrations of 0.00067 and 0.00052 mg/L respectively were obtained. Analysis of the freshly prepared 100 mg/L loading rate WAF at 24 hours, and of the corresponding aged preparation at 48 hours, showed measured test concentrations of less than the limit of quantification (LOQ) of the analytical method employed, determined to be 0.00052 mg/L were obtained.
Given that the toxicity cannot be attributed to a single component or a mixture of components, but to the test item as a whole, the results were based on nominal loading rates only.
Exposure of Daphnia magna to the test item gave EL50 values of greater than 100 mg/L loading rate WAF. The No Observed Effect Loading (NOEL) rate was 100 mg/L loading rate WAF.
It was considered unnecessary and unrealistic to test at concentrations in excess of 100 mg/L.
Description of key information
Key value for chemical safety assessment
Additional information
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