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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 940-766-1 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Remarks:
- a solubilizer was used in this study; However, as the effect values were still above water solubility, the results can be regarded worst case and no effects up to the water solubility at 0.28 mg/L
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 2 003
Materials and methods
- Principles of method if other than guideline:
- Method: no data
- GLP compliance:
- yes
Test material
- Reference substance name:
- (1Z,5E,9E)-cyclododeca-1,5,9-triene
- Molecular formula:
- C12H18
- IUPAC Name:
- (1Z,5E,9E)-cyclododeca-1,5,9-triene
- Details on test material:
- Test substance: 1,5,9-cyclododecatriene, purity 100 %
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- yes
- Remarks:
- acetone
Test organisms
- Test organisms (species):
- Americamysis bahia (previous name: Mysidopsis bahia)
- Details on test organisms:
- TEST ORGANISMS
- Feeding during test: brine shrimp nauplii twice each day
- Control groups: dilution water; solvent 5.0 ml/l acetone
Study design
- Test type:
- static
- Water media type:
- saltwater
- Limit test:
- no
- Total exposure duration:
- 96 h
Test conditions
- Test temperature:
- 22 +/- 1 degree C
- Dissolved oxygen:
- > 60% saturation for first 48 hours, > 40% saturation thereafter
- Nominal and measured concentrations:
- - Nominal concentrations: 0.0625; 0.125; 0.25; 0.5; 1.0 mg/l
- Details on test conditions:
- TEST SYSTEM
- Renewal of test solution: no
- Number of replicates, individuals per replicate: 2 replicates with 10 individuals each
TEST CONDITIONS
- Intensity of irradiation: daylight 40-100 fc - Photoperiod: 16 hours daylight, 8 hours dark - Reference substance (positive control):
- not specified
Results and discussion
Effect concentrations
- Duration:
- 96 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.47 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Remarks on result:
- other: 0.39 - 0.60 mg/l
- Details on results:
- - All deaths occurred within 48 hours
- Other effects: Twitching in all organisms at 1 mg/l
Any other information on results incl. tables
Effect data (Immobilisation):
Test concentration |
Immobile animals / Total |
control |
1/20 |
solvent control |
0/20 |
0.0625 mg/l |
0/20 |
0.125 mg/l |
1/20 |
0.25 mg/l |
0/20 |
0.50 mg/l |
12/20 |
1.0 mg/l |
20/20 |
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The EC50 (96 hours) was calculated to be 0.47 mg/L indicating that the test substance may be very toxic to aquatic invertebrates. However, the effect value is above the limit of water solubility (0.28 mg/L at 20 °C; AQura, 2010). Therefore, no toxic effect is expected up to the limit of water solubility.
- Executive summary:
Daphnia magna were exposed to the test substance over a period of 96 h. Five concentrations ranging from 0.0625 to 1.0 mg/L were tested. The EC50 (96 h) was estimated to be 0.45 mg/L.
The study was assessed as "reliable without restrictions".
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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