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EC number: 290-478-9 | CAS number: 90170-45-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- March 16, 2005 - April 13, 2005
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 005
- Report date:
- 2005
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 E (Ready biodegradability: Modified OECD Screening Test)
- Version / remarks:
- 1992
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- Fraunhofer-Institute for Molecular Biology and Applied Ecology (IME), 57377 Schmallenberg (Germany)
Test material
- Reference substance name:
- L-Alanine, N-coco acyl derivs., sodium salts
- EC Number:
- 290-478-9
- EC Name:
- L-Alanine, N-coco acyl derivs., sodium salts
- Cas Number:
- 90170-45-9
- Molecular formula:
- RHNNaO3
- IUPAC Name:
- L-Alanine, N-coco acyl derivs., sodium salts
- Test material form:
- solid
Constituent 1
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: Ajinomoto Co., Inc., AminoScience Lab. ALG-2, 1-1 Suzuki-Cho, Kawasaki-ku, Kawasaki-Shi, Kanagawa, Japan, 210-8681//Batch/Lot number: 050126BP
- Expiration date of the lot/batch: 01.02.2007
- Purity test date: 17.01.2005
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- sewage, predominantly domestic (adaptation not specified)
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): Fresh samples of secondary effluent were withdrawn on March 16th, 2005 from the sewage treatment plant in 57392 Schmallenberg (Germany), which was mainly fed with municipal wastewater
- Laboratory culture: no
- Preparation of inoculum for exposure: On return to the laboratory the secondary effluent was allowed to settle for 1 h and was then centrifuged. The decanted effluent was kept aerobic until required. - Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 30 mg/L
- Based on:
- DOC
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- DOC removal
- Details on study design:
- TEST CONDITIONS
- Composition of medium: according to OECD 301E
- Additional substrate: no
- Solubilising agent (type and concentration if used): no
- Test temperature: 22 +/- 2°C
- pH: not reported
- pH adjusted: no
- Continuous darkness: yes (diffused light)
TEST SYSTEM
- Culturing apparatus: conical glass flasks
- Number of culture flasks/concentration: 2
- Method used to create aerobic conditions: The secondary effluent was kept aerobic until use in the test
- Measuring equipment: TOC analyser
- Test performed in closed vessels due to significant volatility of test substance: no
- Test performed in open system: yes
SAMPLING
- Sampling frequency: The concentrations of DOC in samples from each flask were determined in duplicate at test start and at day 1, 3, 5, 7, 8, 14, 21, and 28 in a TOC analyser.
CONTROL AND BLANK SYSTEM
- Inoculum blank: performed
- Abiotic sterile control: performed
- Toxicity control: performed
- Other: procedural control with reference item sodium benzoate performed
Reference substance
- Reference substance:
- benzoic acid, sodium salt
- Remarks:
- 30 mg DOC/L
Results and discussion
% Degradation
- Key result
- Parameter:
- % degradation (DOC removal)
- Value:
- 94.4
- Sampling time:
- 28 d
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- The test item proved to be readily biodegradable (91.4% biodegradation after 14 d, 94.4% biodegradation after 28 d).
- Executive summary:
The ready biodegradation of L-Alanine, N-coco acyl derivs., sodium salts was investigated in a study conducted according to OECD Guideline 301 E (Ready biodegradability: Modified OECD Screening Test; 1992) over a period of 28 days and using secondary effluent as inoculum collected from a sewage treatment plant which is mainly fed with municipal wastewater. The biodegradation rate was determined by measurement of DOC removal. Inoculum blank, adsorption control, procedural/functional control with the reference substance sodium benzoate, and toxicity control using 30 mg DOC/L test item and 30 mg DOC/L reference compound were performed.
This study is regarded as reliable without restriction and satisfies the guideline requirements for ready biodegradation.
The test item proved to be readily biodegradable and fulfilling the 10-d-window criterion (91.4% biodegradation after 14 d; 94.4% biodegradation after 28 d of incubation). The functional control reached the pass level > 60% after 14 d. In the toxicity control containing both test and reference item 93.7% biodegradation based on DOC removal occurred within 14 d thus indicating that the test item was not inhibitory at the concentration tested.
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