Registration Dossier
Registration Dossier
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EC number: 278-780-9 | CAS number: 77881-13-1
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
Neither the test substance group animals nor the controls exhibited dermal reactions following challenges with 25% test substance formulation.
Therefore, under the conditions of the test AD-Cyanhydrin showed to be no skin sensitizer.
Migrated from Short description of key information:
Skin Sensitisation, Maximization Test according to Magnusson and Kligman (Guinea pig, GLP, comparable to OECD TG 406): not sensitizing
[Schering AG, Report No. 6628, 1985-06-26]
Justification for classification or non-classification
Based on the study results a classification according to Directive 67/548/EEC and Regulation (EC) No. 1272/2008 (CLP) is not required.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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