Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 272-789-1 | CAS number: 68911-83-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Acute toxicity: oral
A K1 acute oral toxicity test was performed in male and female Sprague Dawley rats according to a guideline similar to OECD Guideline 401 (Gabriel, 1995).
The acute oral LD50 value in male/female Sprague-Dawley rats was >2000 mg/kg bw.
Acute toxicity: inhalation
A K2 acute inhalation toxicity test was performed in male Sprague Dawley rats according to a guideline similar to OECD Guideline 403 (Gabriel, 1974).
The acute oral 1-hr LC50 value in male Sprague-Dawley rats was 3.1 mg/L.
Acute toxicity: dermal
A K2 acute dermal toxicity test was performed in New Zealand whithe rabbit following the OECD 402 Guideline (Gabriel, 1974).
The acute dermal LD50 value rabbits is > 8000 mg/kg bw.
Acute toxicity: other routes
No reliable studies were available for this endpoint.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed
- Dose descriptor:
- LC50
- Value:
- 3 100 mg/m³ air
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
Additional information
Acute toxicity: oral:
Gabriel (1995) performed an acute oral toxicity study (gavage) in Sprague-Dawley rats similar to the OECD 401 test guideline. After exposure to a single dosis, all animals (5 in total) were observed for 14 days. An LD50 value of > 2000 mg/kg bw was determined for male and female rats.
Acute toxicity inhalation:
Gabriel (1974) performed an acute inhalation toxicity study (1 hour whole body exposure, air as vehicle) in male albino rats according to a guideline similar to OECD Guideline 403. From the results obtained in this study, it appears that the substance would be considered to be toxic but not highly toxic by the inhalation route of administration since the LC50 is approximately 3.1 mg/liter.
Acute toxicity: dermal:
Gabriel (1974) performed an acute dermal toxicity study in New Zealand White rabbit according to OECD Guideline 402. After exposure to a single dose of either 1000, 2000, 4000 or 8000 mg/kg, all animals (4 per sex and per dose) were observed for 14 days. An LD50 value of ca. 8000 mg/kg bw was observed.
Acute toxicity: other routes:
No reliable studies were available for this endpoint.
Justification for selection of acute toxicity – oral endpoint
Only one reliable study available
Justification for selection of acute toxicity – inhalation endpoint
Only one reliable study available
Justification for selection of acute toxicity – dermal endpoint
Only one reliable study available
Justification for classification or non-classification
Based on the available data and according to the DSD and CLP criteria the substance should be classified as R23 and for acute inhalation toxicity category 3.
Based on the available data and according to the DSD and CLP criteria the substance should not be classified for acute oral and dermal toxicity.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.