Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 272-271-5 | CAS number: 68784-75-8
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
A LLNA study according to OECD 429 and EC. B.42 guidelines was performed. The SI values calculated for the substance concentrations 10, 25 and 50% were 1.0, 1.4 and 1.1 respectively. Since there was no indication that the test substance elicits an SI ≥ 3 when tested up to 50%, Silicic acid (H2Si2O5), barium salt (1:1), lead-doped was considered not to be a skin sensitizer in the LLNA. It was established that the EC3 value (the estimated test substance concentration that will give a SI =3) (if any) exceeds 50%.
Migrated from Short description of key information:
The substance showed to be not sensitising in a LLNA study.
Justification for classification or non-classification
Based on these available data, Silicic acid(H2Si2O5), barium salt(1:1), lead-doped does not have to be classified for skin sensitisation according to Directive 67/548/EC or the CLP Regulation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
