Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 268-597-2 | CAS number: 68130-55-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
- Remarks:
- Chemical analyses were based on limited number of measured samples and analytical limit of GC detection and quantitation.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- GLP compliance:
- yes
- Test organisms (species):
- Daphnia sp.
- Details on test organisms:
- TEST ORGANISM
- Common name: Daphnia magna - Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 48 h
- Hardness:
- 200 mg/L (CaCO3)
- Test temperature:
- 19.8-20.0C
- pH:
- 8.22-8.48
- Dissolved oxygen:
- 60% of saturation (7.1-7.9 mg O2/L)
- Nominal and measured concentrations:
- 0, 324, 1296 and 5076 mg/L (nominal concentration)
WAF is the maximum soluble concentration of the nominal test concentrations after 20 hours of stirring and 4 hours of equilibrating. Only the water phase was used in the definitive test solutions. - Details on test conditions:
- - Photoperiod: 16 hr light / 8 hr dark cycle
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 5 076 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: WAF is the maximum soluble concentration of the nominal test concentrations after 20 hours of stirring and 4 hours of equilibrating. Only the water phase was used in the definitive test solutions.
- Details on results:
- - Mortality of control: No significant immobilization or adverse symptom was observed in the daphnids at any of the tested WAFs compared with controls.
GC-FID analysis for WAF solutions gave limited results due to the limit of GC detection (ca. 10 mg/L). However, several samples showed measurable concentrations (11-13 mg/L) slightly above the GC limit of detection. The test material has limited water solubility (calculated to be 8.16 x 10-8 mg/L, using EpiWin). - Reported statistics and error estimates:
- Binomial probability analysis (Stephan et al., 1978): Fisher's exact test
- Validity criteria fulfilled:
- yes
- Conclusions:
- 48-hr EC50 was > 5076 mg/L WAF (nominal loading rate). No significant immobilization or adverse symptom was observed in the daphnids at any of the tested WAFs compared with controls. Test material could be detectable in the some of the WAF solutions but was close to the limit of analytical detection. The test material has limited water solubility and would be expected to be close to water-saturated levels (WSL) in the tested solutions. The data suggest that test substance would not be expected to cause immobilization at or close to its water saturation levels or water solubility limits (WSL).
Reference
WAF Solution Conc. Nominal load rate (mg/L) |
Immobility % (48-hr) |
0 Control (untreated) |
5% |
324 | 0 |
648 | 5 |
1296 | 0 |
2592 | 0 |
5076 | 0 |
Description of key information
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 5 000 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.