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EC number: 268-597-2 | CAS number: 68130-55-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2017-06-02 - 2017-09-25
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 017
- Report date:
- 2017
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Version / remarks:
- 1992
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Hexanedioic acid, mixed esters with decanoic acid, heptanoic acid, octanoic acid and pentaerythritol
- EC Number:
- 268-597-2
- EC Name:
- Hexanedioic acid, mixed esters with decanoic acid, heptanoic acid, octanoic acid and pentaerythritol
- Cas Number:
- 68130-55-2
- Molecular formula:
- C36H64O10
- IUPAC Name:
- 6-[3-(decanoyloxy)-2-[(heptanoyloxy)methyl]-2-[(octanoyloxy)methyl]propoxy]-6-oxohexanoic acid
- Test material form:
- liquid
Constituent 1
- Specific details on test material used for the study:
- Batch number: 026X6
Purity: > 99%/UVCB
Water solubility: insoluble
Realative Density: 0.97 (at 25 °C)
ThOD*: 2.48 mg O2/mg
Appearance: Light yellow liquid
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, non-adapted
- Details on inoculum:
- Municipal sewage treatment plant, 31137 Hildesheim, Germany.
Activated sludge from the sewage plant at Hildesheim is well suited as it receives predominantly municipal sewage and hardly
any industrial chemical waste.
Receipt: 2017-06-15
Pretreatment:
The activated sludge was washed twice with chlorine free tap water.
After the second washing the settled sludge was resuspended in mineral salts medium and was maintained in an aerobic condition
by aeration for 2 hours. Thereafter the sludge was homogenized with a blender. After sedimentation the supernatant was decanted
and maintained in an aerobic condition by aeration with CO2-free air for 7 days. 10 ml/L were used to initiate inoculation.
Colony forming units in the test vessels: Approx. 10E7 - 10E8 CFU/l - Duration of test (contact time):
- 28 d
Initial test substance concentrationopen allclose all
- Initial conc.:
- 21 mg/L
- Based on:
- test mat.
- Initial conc.:
- 52.1 other: mg O2/l
- Based on:
- ThOD
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST CONDITIONS
- Composition of medium: Mineral salts medium according to OECD 301 F
- Test temperature:
Nominal: 20 - 24, ± 1 °C; Actual: 20.0 - 20.6 °c
Occasionally below 20 °C (19.9 °C) for short periods.
- pH: 7.74 - 7.97
- pH adjusted: no
- CEC (meq/100 g):
- Dispersion treatment: Continuous stirring
- Suspended solids concentration:
- Continuous darkness: yes
TEST SYSTEM
- Number of culture flasks/concentration:
• two for the inoculum control (C1, C2)
• one for the functional control (R1)
• two for the test item (P1, P2)
• one for the toxicity control (T1)
Separate replicates of test item and toxicity control were prepared
for measurement of the pH-value at test start:
• one for the test item (PpH)
• one for the toxicity control (TpH)
- Method used to create aerobic conditions: Continuous stirring
- Measuring equipment:
OxiTop® OC110 controller with software Achat OC, WTW
OxiTop® measuring heads, WTW
SAMPLING
- Sampling frequency and Sampling method:
The oxygen consumption was determined in the incubation
vessels by the OxiTop® measuring system at 360 measuring
points (every 112 minutes) during the 28 d incubation period.
CONTROL AND BLANK SYSTEM
- Inoculum control: Test medium without test and / or reference item
- Toxicity control: Test and reference item (in test concentration) in test medium
Reference substance
- Reference substance:
- benzoic acid, sodium salt
Results and discussion
% Degradation
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 53
- Sampling time:
- 28 d
BOD5 / COD results
- Results with reference substance:
- The pass level for ready biodegradation (~ 60% degradation) was reached within 3 days. The
validity criterion that the degradation should be~ 60% after 14 d was fulfilled.
Stages of Biodegradation: The adaptation phase changed to degradation phase within 2 days
(degradation> 10%) and the biodegradation came to a maximum of 97% on day 28.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- After a test period of 28 days, the test item is classified as not readily biodegradable within the 28 day period of the study.
- Executive summary:
The test item reached the 10% level (beginning of biodegradation) on day 3.
The 60% pass level was not reached within the 28 day period of the study. The mean biodegradation on day 28 was 53%.
After a test period of 28 days, the test item is classified as not readily biodegradable within the 28 day period of the study.
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