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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Boiling point

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
April 26, 2012 - May 31, 2012
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Comparable to guideline study (OECD103) with acceptable restrictions
Qualifier:
according to guideline
Guideline:
EU Method A.2 (Boiling Temperature)
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 103 (Boiling point/boiling range)
Deviations:
no
GLP compliance:
no
Type of method:
differential thermal analysis
Key result
Decomposition:
yes
Decomp. temp.:
>= 178 °C

A broad exothermal effect could be observed in a temperature range of 160 – 350 °C with a decomposition energy of -100 J/g (mean value).

Results on melting and boiling point

No.

Start of effect / °C

Energy /
J/g

Remark

File 512-0315-01-a.L01

178

-100 (exothermal)

Conclusions:
According to OECD Test Guidelines 102 and 103, and EC No. 440/2008 Part A. Method A.1. and A.2., the test item 7-Aminocephalosporanic acid has no melting and no boiling point at atmospheric pressure (1013 hPa). It decomposes firstly at a temperature of 178 °C.
Executive summary:

The test item decomposes at 178 °C, without melting.

Description of key information

The test item decomposes at >=181 °C, without melting.

Key value for chemical safety assessment

Additional information