Registration Dossier
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EC number: 233-713-2 | CAS number: 10326-41-7
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- weight of evidence
- Justification for type of information:
- For details and justification of read-across please refer to the read-across report attached to IUCLID section 13.
- Reason / purpose for cross-reference:
- read-across source
- Melting / freezing pt.:
- >= 52.7 - <= 52.8 °C
- Conclusions:
- The melting point of L-lactic acid is 53 °C.
- Executive summary:
According to Holten, L-lactic acid has a melting point of 53 °C.
This information is used in a read-across approach in the assessment of the target substance.
For details and justification of read-across please refer to the attached report in section 13 of IUCLID.
- Endpoint:
- melting point/freezing point
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- weight of evidence
- Justification for type of information:
- For details and justification of read-across please refer to the read-across report attached to IUCLID section 13.
- Reason / purpose for cross-reference:
- read-across source
- Key result
- Melting / freezing pt.:
- < -80 °C
- Atm. press.:
- ca. 1 atm
- Remarks on result:
- other: VIscous solutions do not solidify
- Conclusions:
- 93 % solutions of lactic acid do not solidify.
- Executive summary:
93 % solutions of lactic acid do not solidify.
This information is used in a read-across approach in the assessment of the target substance.
For details and justification of read-across please refer to the attached report in section 13 of IUCLID.
- Endpoint:
- melting point/freezing point
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- weight of evidence
- Justification for type of information:
- This information is used in a read-across approach in the assessment of the target substance. For details and justification of read-across please refer to the read-across report attached to IUCLID section 13.
- Reason / purpose for cross-reference:
- read-across source
- Melting / freezing pt.:
- 53 °C
- Conclusions:
- Melting point of L-lactic acid = 53 °C
- Executive summary:
Chirally pure lactic acid has a melting point of 53 °C. Mixtures of R- and S-lactic acid have a decreased melting point, with a eutectic point at a 50:50 mixture at 18 °C.
This information is used in a read-across approach in the assessment of the target substance. For details and justification of read-across please refer to the read-across report attached to IUCLID section 13.
- Endpoint:
- melting point/freezing point
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- weight of evidence
- Justification for type of information:
- This information is used in a read-across approach in the assessment of the target substance. For details and justification of read-across please refer to the read-across report attached to IUCLID section 13.
- Reason / purpose for cross-reference:
- read-across source
- Melting / freezing pt.:
- 53 °C
- Conclusions:
- The melting point of L-lactic acid is 53 °C
- Executive summary:
The melting point of L-lactic acid has been determined in dependence of the percentage of (R)-lactic acid and (S)-lactic acid in the mixture. The melting point of L-lactic acid has been determined to be 53 °C.
This information is used in a read-across approach in the assessment of the target substance. For details and justification of read-across please refer to the read-across report attached to IUCLID section 13.
Referenceopen allclose all
Table 1: melting point of the mixtures of lactic acid
Melting point of the mixtures of lactic acid |
|||||||
Mixtures |
R/S 50 % / 50 % |
RS 45 % / 55 % |
RS 40 % / 60 % |
RS 30 % / 70 % |
RS 20 % / 80 % |
RS 10 % / 90 % |
RS 0 % / 100 % |
Melting point (°C) |
18.0 |
22.5 |
27.5 |
35.0 |
41.5 |
47.0 |
53.0 |
Description of key information
Melting point of crystalline lactic acid is 53 °C.
Concentrated aqueous solutions of lactic acid do not solidify.
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- 53 °C
Additional information
Commercial manufacture of lactic acid does not result in solid (crystalline) material. Lactic acid is produced as an aqueous solution at concentrations of up to 93%. Due to the high viscosity of these solutions they do not solidify upon cooling. Also see additional information under "viscosity".
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
