Registration Dossier
Registration Dossier
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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 228-788-3 | CAS number: 6358-87-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Toxicity to terrestrial arthropods
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to bees: acute contact
- Data waiving:
- other justification
- Justification for data waiving:
- other:
- Endpoint:
- toxicity to bees: chronic oral
- Data waiving:
- exposure considerations
- Justification for data waiving:
- the study does not need to be conducted because direct and indirect exposure of the soil compartment is unlikely
- Justification for type of information:
- The substance is not supposed to be directly applied to soil. Based on the PC properties of the substance (extremely low solubility in water and octanol), a low adsorption potential is indicated. Therefore, binding to sewage sludge is unlikely and as a consequence a transfer to the soil compartment is not expected. Therefore it can be assumed that there is no direct and indirect exposure to the environment. Furthermore, due to their physico-chemical properties and very low (bio)solubility the Diazopyrazolone Pigments are considered to be not bioavailable. This is supported by the absence of toxicity in long term experiments with earthworms and sediment worms.
- Endpoint:
- toxicity to bees: acute oral
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- a short-term study does not need to be conducted because an appropriate long-term toxicity study on terrestrial organisms is available
- Justification for type of information:
- there is a long-term study available (OECD 222)
Referenceopen allclose all
Description of key information
Direct and indirect exposure of the soil compartment is unlikely. In addition, there is no indication for any toxicity of the test substance, neither in tests on earthworms (Eisenia fetida) and sediment worms nor in tests on aquatic organisms of all trophic levels (acute and chronic). Furthermore, the outcome of the CSA indicates that the available terrestrial toxicity tests are appropriate to cover the information requirements. Therefore no further terrestric studies are necessary.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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