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EC number: 222-883-3 | CAS number: 3648-18-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
96 hour LC50 (dioctyltin oxide) > water solubility, OECD 203, EU Method C.1, Hooftman & de Wolf (2004a).
96 hour LC50 (lauric acid) = 23 mg/L, HERA Human & Environmental Risk Assessment (2003).
Key value for chemical safety assessment
Additional information
Since no data are available on the substance itself information has been read across to the products of its hydrolysis, dioctyltin oxide and lauric acid.
The acute toxicity of dioctyltin oxide to Brachydanio rerio (zebra fish) was determined in a semi-static test conducted in accordance with standardised guidelines and under GLP conditions. Due to the insolubility of the test material the study was performed with a water soluble fraction as a limit test. Under the conditions of the study, the 96 h LC50 of the test material was found to be greater than the water solubility of the test material. The study was assigned a reliability score of 2 in accordance with the principles for assessing data quality as defined by Klimisch (1997).
Information on the acute toxicity of lauric acid to fresh-water fish is available in the Human & Environmental Risk Assessment (2003) report on ingredients of European household cleaning products. Two LC50 values were reported, 63.3 mg/L in Lepomis macrochirus and 8.6 mg/L in an unreported species. The geometric mean of the available data was determined to be 23mg/L. No information is provided on materials and methods. Accordingly this report was assigned a reliability score of 4 in line with Klimisch (1997).
Given the available data on the hydrolysis products of the substance to be registered, the LC50 can be expected to be greater than the water solubility of the test material.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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