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EC number: 212-377-0 | CAS number: 811-97-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Distribution modelling
Administrative data
- Endpoint:
- distribution modelling
- Adequacy of study:
- key study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 003
Materials and methods
- Model:
- other: Calculation according to Mackay Level 1 and Level III
Test material
- Reference substance name:
- Norflurane
- EC Number:
- 212-377-0
- EC Name:
- Norflurane
- Cas Number:
- 811-97-2
- Molecular formula:
- C2H2F4
- IUPAC Name:
- 1,1,1,2-tetrafluoroethane
Constituent 1
Results and discussion
Percent distribution in media
- Air (%):
- 99.93
- Water (%):
- 0.07
- Soil (%):
- 0.01
- Sediment (%):
- 0
Any other information on results incl. tables
EQC level III (Emission to air alone)
Applicant's summary and conclusion
- Conclusions:
- HFC-134a released to air would remain almost exclusively in that compartment and, when released to, water would be expected to partition ultimately partition predominantly to the ambient air. Moreover, any HFC-134a present in surface or ground waters would have little tendency to partition to biota or soil.
- Executive summary:
The environmental partitioning of HFC-134a has been assessed (Franklin, 2003) using the EQC Level I and Level III models (Mackay et al, 1996).
In the Level I model, a fixed quantity of a supposedly non-degradable chemical is introduced into a closed evaluative environment and equilibrium achieved between the various environmental compartments (air, water, soil, sediment). The Level III model simulates a situation in which a chemical is emitted at a constant rate into one or more of the compartments, in each of which it may degrade; the steady-state distribution between compartments is then calculated. Due to the resistance to mass transfer between compartments, the various phases are not in equilibrium and the steady-state partitioning depends on its "mode of entry", i.e. the compartment(s) into which the chemical is injected. EQC modelling has been performed for HFC-134a using the physical properties and an atmospheric lifetime of 14.0 years, corresponding to a half-life of 9.7 years. Degradation in other media was not taken into account. The table below gives the percentage of HFC-134a calculated for each compartment.
Compartment EQC Level 1 EQC level III EQC Level III Enmission to air alone Emmission to water alone Air 99.91 99.93 19.9 Water 0.092 0.067 79.9 Soil 0.00094 0.0070 0.0014 Sediment 0.00002 0.00015 0.18 The Level III simulation with emissions of HFC-134a to air alone leads to a distribution close to the Level I equilibrium situation as far as the air and water compartments are concerned. However, a much greater steady-state proportion of HFC-134a is found in the water compartment when the emissions are to water alone. This is due to the resistances to inter-media transfer (in particular from water to air) introduced in the Level III model. Thus, HFC-134a released to air would remain almost exclusively in that compartment and, when released to, water would be expected to partition ultimately partition predominantly to the ambient air. Moreover, any HFC-134a present in surface or ground waters would have little tendency to partition to biota or soil.
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