Registration Dossier
Registration Dossier
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EC number: 201-084-3 | CAS number: 78-11-5
Biodegradation in water and sediment: simulation tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: simulation testing on ultimate degradation in surface water
- Data waiving:
- study technically not feasible
- Justification for data waiving:
- the study does not need to be conducted because the substance is highly insoluble in water
- Justification for type of information:
- PETN is highly insoluble in water (water solubility <43 mg/L).
- Transformation products:
- not specified
- Endpoint:
- biodegradation in water: sediment simulation testing
- Data waiving:
- study technically not feasible
- Justification for data waiving:
- other:
- Justification for type of information:
- Pentaerythritol tetranitrate (PETN) is a highly explosive organic compound belonging to the same chemical family as nitroglycerin and nitrocellulose. PETN is a sensitive compound and is easily detonated by an appropriate mechanical shock or when it is exposed to heat. It retains its properties in storage for longer periods than do nitroglycerine and nitrocellulose. According to REACH annex XI, section, 2, testing for a specific endpoint may be omitted, if it is technically not possible to conduct the study as a consequence of the properties of the substance: e.g. very volatile, highly reactive or unstable substances cannot be used, mixing of the substance with water may cause danger of fire or explosion or the radio-labelling of the substance required in certain studies may not be possible. This exemption (unstable substance) shall be applicable to PETN because it is “an unstable explosive” (as per CLP, hazard statement H200). Submitting the substance to testing would pose an extreme risk to the laboratory personnel and facilities due to explosive nature of the substance. Please find more information attached in IUCLID section 13.2.
- Transformation products:
- not specified
Referenceopen allclose all
Description of key information
Simulation testing on ultimate degradation in surface water study does not need to be conducted since PETN is highly insoluble in water. Due to explosive properties of the substance, no further testing could be conducted.
Key value for chemical safety assessment
Additional information
PETN is a sensitive compound and is easily detonated by an appropriate mechanical shock or when it is exposed to heat. Submitting the substance to testing would pose an extreme risk to the laboratory personnel and facilities due to explosive nature of the substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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