Registration Dossier
Registration Dossier
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EC number: 200-896-5 | CAS number: 75-73-0
Endpoint summary
Administrative data
Key value for chemical safety assessment
- Toxic effect type:
- dose-dependent
Effects on fertility
Description of key information
The three analogues used for the read-across (trifluoromethane, pentafluoroethane and perfluoroethane) presented several reliable reproductive toxicity studies, including prenatal developmental toxicity studies (OECD 414) and a combined repeated dose toxicity study with the reproduction and developmental toxicity screening (OECD 422), showing overall evidence that none of them is reprotoxic. As the read-across with these analogues is considered as approriate, the target substance carbon tetrafluoride is not expected to induce a reproductive toxicity.
Considering the NOAELs of the mentioned studies, it can be stated that the NOAEL of carbon tetrafluoride is similar to these values (i.e 50.000 ppm).
Justification for classification or non-classification
Additional information
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