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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 200-812-7 | CAS number: 74-82-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Non GLP, TGD guideline, QSAR calculation, acceptable with restriction
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- The Estimation Programs Interface (EPI) SuiteTM v4.00
- Author:
- US Environmental Protection Agency's Office of Pollution Prevention and Toxics and Syracuse Research Corporation (SRC)
- Year:
- 2 008
- Bibliographic source:
- United States Environmental Protection Agency
Materials and methods
- Principles of method if other than guideline:
- The Ecosar class program has been developed primarily for the evaluation of neutral organic compounds and organic classes with excess toxicity. The QSARs in the Ecosar program are developed for chemical classes based on measured test data that have been submitted by industry or they are developed by other sources for chemicals with similar structures, e.g. phenols. Using the measured aquatic toxicity values and estimated Kow values, regression equations can be developed for a class of chemicals. Toxicity values for new chemicals may then be calculated by inserting the Kow into the regression equation and correcting the resultant value for the molecular weight of the compound.
- GLP compliance:
- no
Test material
- Reference substance name:
- Reference substance 002
- Cas Number:
- 74-84-0
- Molecular formula:
- C2H6
- Details on test material:
- Estimate used neutral organics ECOSAR class
Constituent 1
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
No data reported
Sampling and analysis
- Analytical monitoring:
- not required
- Details on sampling:
- No data reported
Test solutions
- Vehicle:
- not specified
- Details on test solutions:
- No data reported
Test organisms
- Test organisms (species):
- other: Fish, no other information
- Details on test organisms:
- No data reported
Study design
- Test type:
- other: QSAR calculation
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
- Post exposure observation period:
- No data reported
Test conditions
- Hardness:
- No data reported
- Test temperature:
- No data reported
- pH:
- No data reported
- Dissolved oxygen:
- No data reported
- Salinity:
- No data reported
- Nominal and measured concentrations:
- No data reported
- Details on test conditions:
- No data reported
- Reference substance (positive control):
- not specified
Results and discussion
Effect concentrations
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 91.42 mg/L
- Nominal / measured:
- estimated
- Conc. based on:
- test mat.
- Basis for effect:
- not specified
- Details on results:
- The value estimated is greater than the solubility of ethane in water.
- Results with reference substance (positive control):
- No data reported
- Reported statistics and error estimates:
- No data reported
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not applicable
- Remarks:
- Calculation
- Conclusions:
- The 96 hour LC50 for fish is estimated to be 91.42 mg/L in fresh water. The value estimated is greater than the solubility of ethane in water.
- Executive summary:
No experimental data are available for the effect of ethane on the short term toxicity of fish so QSAR calculations have been used to estimate result. ECOSAR Program v1.00. in EPI Suite v4.00 was used which is acceptable with restrictions. The 96 hour LC50 for fish is estimated to be 91.42 mg/L in fresh water. The value estimated is greater than the solubility of ethane in water.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.