Brief Profile

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
214-317-9
CAS no.:
1120-71-4
Index number:
016-032-00-3
Molecular formula:
C3H6O3S
SMILES:
O=S1(=O)CCCO1
InChI:
InChI=1S/C3H6O3S/c4-7(5)3-1-2-6-7/h1-3H2
Type of substance:
Mono constituent substance
Origin:
Organic
Registered compositions:
13
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance may cause cancer, is harmful if swallowed and is harmful in contact with skin.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance is toxic if swallowed, is toxic in contact with skin, causes serious eye damage, is harmful if inhaled, is suspected of causing genetic defects and causes skin irritation.

Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance is harmful to aquatic life with long lasting effects.

Breakdown of all 222 C&L notifications submitted to ECHA

Carc. 1B H350 Harmonised Classification
Acute Tox. 3 H301
Acute Tox. 3 H311
Eye Dam. 1 H318
Acute Tox. 4 H332
Muta. 2 H341
Skin Irrit. 2 H315
Aquatic Chronic 3 H412
Acute Tox. 4 H312 Harmonised Classification
Acute Tox. 4 H302 Harmonised Classification
Eye Irrit. 2 H319
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

  • C
Officially recognised in the EU as Carcinogenic (Harmonised C&L, Candidate list of SVHCs).
  • C
There is broad agreement in that a majority of data submitters agree this substance is Carcinogenic (100% of REACH registrations).

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 13 active registrations under REACH, 1 Joint Submission(s) and 1 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Substance of very high concern (SVHC) and included in the candidate list for authorisation.
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Industrial accident prevention and reporting requirements have been established for this substance.
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 to < 1 000 tonnes per annum.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: electrolytes for batteries.

Other release to the environment of this substance is likely to occur from: indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

This substance is used in the following activities or processes at workplace: the low energy manipulation of substances bound in materials or articles.

Other release to the environment of this substance is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

This substance can be found in complex articles, with no release intended: electrical batteries and accumulators.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used for the manufacture of: electrical, electronic and optical equipment.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

Other release to the environment of this substance is likely to occur from: indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

This substance is used in the following products: electrolytes for batteries and photo-chemicals.

This substance is used in the following activities or processes at workplace: closed processes with no likelihood of exposure, transfer of chemicals at dedicated facilities, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: formulation of mixtures.

This substance is used in the following products: electrolytes for batteries.

This substance is used in the following areas: scientific research and development. This substance is used for the manufacture of: electrical, electronic and optical equipment, machinery and vehicles and chemicals.

This substance is used in the following activities or processes at workplace: closed processes with no likelihood of exposure, closed batch processing in synthesis or formulation, closed, continuous processes with occasional controlled exposure, transfer of chemicals at dedicated facilities and laboratory work.

Release to the environment of this substance can occur from industrial use: of substances in closed systems with minimal release, in the production of articles, in processing aids at industrial sites and as an intermediate step in further manufacturing of another substance (use of intermediates).

This substance is used in the following activities or processes at workplace: closed processes with no likelihood of exposure, transfer of chemicals at dedicated facilities and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: obtain special instructions before use; wash parts of the body (as specified by manufacturer/supplier)in contact with substance thoroughly after handling; do not breathe the dust, fume, gas, mist, vapours or spray; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If on skin (or hair): take off immediately all contaminated clothing. Rinse skin with water or shower. If exposed or concerned: get medical advice/attention. If on skin: wash with soap and water. If in eyes: rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing.

Storage statements

Store this substance locked up.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • Central Glass Czech s.r.o., Evropská 859/115a 160 00 Praha6 Czech Republic
  • Chemical Inspection & Regulation Service Limited, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED (data owner), Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED(Wuhan Pinestone Technology Co., Ltd.), Regus Harcourt Centre D02 HW77 Dublin Ireland
  • Dongwha Electrolyte Hungary Kft., 067/4 hrsz. 2038 Sóskút Hungary
  • Raschig GmbH, Mundenheimerstraße 100 D-67061 Ludwigshafen Germany
  • REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland
  • Soulbrain HU Kft., Bánki Donát 3. 2800 Tatabánya Hungary
  • TÜV SÜD Iberia S.A.U., Ronda Can Fatjó 13 08290 Cerdanyola del Vallès Barcelona Spain
  • UBE Corporation Europe, S.A.U. (OR2), Polígono Industrial El Serrallo s/n 12100 Castellón CASTELLON Spain
  • [Confidential], [Confidential]
  • BASF Schwarzheide GmbH, Schipkauer Str. 1 01987 Schwarzheide Brandenburg Germany
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • GBK Gefahrgutbuero GmbH, Konrad Adenauer Str. 30 55218 Ingelheim Germany

Substance names and other identifiers

1,2-Oxathiolane, 2,2-dioxide
Other
1,2-Oxathrolane 2,2-dioxide
Other
1,3-Propane sultone
Other
1,3-propanesultone
EC Inventory, Candidate list, REACH pre-registration, Other
1,3-Propanesultone
Candidate list, REACH pre-registration, Other, Cosmetic Products Regulation, Annex II - Prohibited Substances
1,3-propanesultone 1,2-oxathiolane 2,2-dioxide
C&L Inventory
1,3-propanesultone; 1,2-oxathiolane 2,2-dioxide
FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work
1-Propanesulfonic acid, 3-hydroxy-, gamma-sultone
Other
3-Hydroxy-1-propanesulfonic acid gamma-sultone
Other
3-Hydroxy-1-propanesulphonic acid sultone
Other
3-Hydroxythietane-1,1-Dioxide
Other
Propane sultone
Other
1,3-propaanisultoni (fi)
C&L Inventory
1,3-propaansulton (nl)
C&L Inventory
1,3-propaansultoon 1,2-oksatiolaan-2,2-dioksiid (et)
C&L Inventory
1,3-propanesultone;2,2-dioxyde de 1,2-oxathiolane (fr)
C&L Inventory
1,3-propanossultona (pt)
C&L Inventory
1,3-propanosulton 2,2-dioksy-1,2-oksatiolan (pl)
C&L Inventory
1,3-propansulton (da)
C&L Inventory
1,3-propansulton (no)
C&L Inventory
1,3-propansulton (sv)
C&L Inventory
1,3-propansulton 1,2-oksatiolan 2,2-dioksid (sl)
C&L Inventory
1,3-Propansulton 1,2-Oxathiolan 2,2-dioxid (de)
C&L Inventory
1,3-propansulton 1,2-oxatiolan 2,2-dioxid (ro)
C&L Inventory
1,3-propansultona (es)
C&L Inventory
1,3-propansultonas 1,2-oksatiolano 2,2-dioksidas (lt)
C&L Inventory
1,3-propansultone (it)
C&L Inventory
1,3-propánszulton 1,2-oxatiolán-2,2-dioxid (hu)
C&L Inventory
1,3-propānsultons 1,2-oksatiolāna 2,2-dioksīds (lv)
C&L Inventory
1,3-προπανοσουλτόν (el)
C&L Inventory
1,3-пропансултон 1,2-оксатиолан 2,2-диоксид (bg)
C&L Inventory
propan-1,3-sulton 1,2-oxathiolan-2,2-dioxid (cs)
C&L Inventory
propán-1,3-sultón 1,2-oxatiolán-2,2-dioxid (sk)
C&L Inventory
1,2-Oxathiolane 2,2-Dioxide
C&L Inventory, Registration dossier
1,2lambda6-oxathiolane-2,2-dione
Registration dossier, Other
1,2λ6-oxathiolane-2,2-dione
Registration dossier
1,3-Propane sultone
C&L Inventory
1,3-Propanesultone
C&L Inventory, Registration dossier
1,3-Propanesultone
C&L Inventory, Registration dossier
1,3-Propansulton
C&L Inventory
oxathiolane 2,2-dioxide
Registration dossier, Other
Propane Sultone
C&L Inventory
1,3-propanesultone
Registration dossier
016-032-00-3
Index number
C&L Inventory
1120-71-4
CAS number
EC Inventory, C&L Inventory, Candidate list, Registration dossier, REACH pre-registration, Other, FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Regulation - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Medical Devices Regulation - Hazardous Substances, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 10 studies submitted
  • 5 studies processed
C Physical state at 20°C and 1013 hPa
Solid (100%) [5]
C Form
Powder (80%), Crystalline (20%) [5]
C Odour
Other (100%) [5]
C Substance type
Organic (100%) [5]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence 6
Other 2 1
Data waiving
no waivers
C Summaries
  • 3 summaries submitted
  • 3 summaries processed
Physical state at 20°C and 1013 hPa
Solid (100%)

Melting/freezing point

Study results
  • 10 studies submitted
  • 6 studies processed
R Melting / freezing point
31 °C [6]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence 6
Other 2 1
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 2 summaries processed
Melting / freezing point at 101 325 Pa
31 °C

Boiling point

Study results
  • 10 studies submitted
  • 1 study processed
R Boiling point
112 - 203.85 °C @ 39.997 - 1 013 hPa [2]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other 4 1
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
R Summaries
  • 3 summaries submitted
  • 1 summary processed
Boiling point at 101 325 Pa
204 °C

Density

Study results
  • 10 studies submitted
  • 8 studies processed
R Density
1.39 - 1.392 g/cm³ @ 40 °C [3]
R Relative density
1.392 - 1.393 @ 40 °C [5]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence 6
Other 1 1
Data waiving
no waivers
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Vapour pressure

Study results
  • 8 studies submitted
  • 4 studies processed
R Vapour pressure
0.27 - 51.2 Pa @ 20 - 50 °C [10]

Type of Study provided
Studies with data
Key study 3 1
Supporting study 1
Weight of evidence
Other 2 1
Data waiving
no waivers
R Summaries
  • 4 summaries submitted
  • 4 summaries processed
Vapour pressure
0.001 - 0.48 Pa @ 20 - 25 °C

Partition coefficient

Study results
  • 9 studies submitted
  • 1 study processed
R Log Pow
-0.28 - -0.279 [2]

Type of Study provided
Studies with data
Key study 1
Supporting study 4
Weight of evidence
Other 2
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
R Summaries
  • 4 summaries submitted
  • 2 summaries processed
Log Kow (Log Pow)
-2.86 - -0.28 @ 20 °C

Water solubility

Study results
  • 9 studies submitted
  • 1 study processed
R Water solubility (mass/vol.)
170.7 - 415.11 g/L @ 25 °C and pH 7 [2]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other 3 2
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
R Summaries
  • 4 summaries submitted
  • 2 summaries processed
Water solubility
171 - 1 000 g/L @ 25 °C

Solubility in organic solvents / fat solubility

Study results
  • 5 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 3 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Surface tension

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 2
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 6 studies submitted
  • 2 studies processed
R Flash point
110 - 171.5 °C @ 100.4 - 101.3 kPa [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other 1 1
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Auto flammability

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 2
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 14 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 12
Exposure cons.
Other
C Summaries
  • 3 summaries submitted
  • 3 summaries processed
Flammability
Non flammable (100%)

Explosiveness

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
C Summaries
  • 3 summaries submitted
  • 3 summaries processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 2
C Summaries
  • 3 summaries submitted
  • 3 summaries processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers

No summary exists for this scientific endpoint

Dissociation constant

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 2
Sci. unjustified
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 3 studies submitted
  • 2 studies processed
R Dissipation half life (DT50)
59.58 h [2]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 2 summaries processed
Half life in air
59.58 - 119.208 h

Hydrolysis

Study results
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 3 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 7 studies submitted
  • 3 studies processed
C Interpretation of results
Readily biodegradable (100%) [3]

Type of Study provided
Studies with data
Key study 2 1 1
Supporting study
Weight of evidence 2
Other 1
Data waiving
no waivers
C Summaries
  • 3 summaries submitted
  • 3 summaries processed
Biodegradation in water
Readily biodegradable (67%), Under test conditions no biodegradation observed (33%)

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: aquatic / sediment

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 4 studies submitted
  • 1 study processed
R Koc
16.8 L/kg [1]
R log Koc
1.23 dimensionless [1]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence 1
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 1 summary processed
Koc at 20°C
16.8

Henrys law constant (H)

Study results
  • 3 studies submitted
  • 3 studies processed
R H - dimensionless
0 @ 25 °C and 101.3 kPa [1]
R H - (pressure) m³/mol
0.239 - 0.239 Pa m³/mol @ 25 °C and 101.3 kPa [3]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 2 summaries processed
Henry's law constant
0 - 0.239 Pa.m³.mol-1 @ 25 °C

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 2 summaries submitted
  • 2 summaries processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 16 µg/L (2)
Intermittent releases (freshwater) 160 µg/L (2)
Marine water 1.6 µg/L (2)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 26 mg/L (2)
Sediment (freshwater) 69 - 84.5 µg/kg sediment dw (2)
Sediment (marine water) 6.9 - 8.45 µg/kg sediment dw (2)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil 4.52 - 7.5 µg/kg soil dw (2)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (1)

Short–term toxicity to fish

Study results
  • 7 studies submitted
  • 5 studies processed
P/RResults
LC50 (4 days) 72.5 - 630 mg/L [5]
LC0 (4 days) 32 mg/L [2]
LC100 (4 days) 100 mg/L [2]
NOEC (4 days) 32 - 180 mg/L [3]

Type of Study provided
Studies with data
Key study 1 2
Supporting study 1
Weight of evidence 2 1
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 4 studies submitted
  • 1 study processed
P/RResults
LC50 (14 days) 1 470 g/L [1]

Type of Study provided
Studies with data
Key study 3
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Short–term toxicity to aquatic invertebrates

Study results
  • 4 studies submitted
  • 4 studies processed
P/RResults
EC50 (48 h) 16 - 33 mg/L [3]
EC50 (24 h) 39 mg/L [1]
LC50 (4 days) 1.598 g/L [1]
LC50 (48 h) 920 mg/L [1]
NOEC (48 h) 9 - 18 mg/L [3]

Type of Study provided
Studies with data
Key study 2 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to aquatic algae and cyanobacteria

Study results
  • 6 studies submitted
  • 3 studies processed
P/RResults
EC50 (4 days) 501 - 592 mg/L [2]
EC50 (72 h) 320 mg/L [1]
EC10 (72 h) 320 mg/L [1]

Type of Study provided
Studies with data
Key study 1 1 2
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for freshwater algae
320 mg/L
EC10 or NOEC for freshwater algae
320 mg/L

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
EC50 (17 h) 80 - 90 mg/L [4]
EC10 (17 h) 26 - 44 mg/L [4]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 2 summaries submitted
  • 2 summaries processed
EC50 for microorganisms
26 - 80 mg/L

Sediment toxicity

Data not provided by the registrant

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
LC50 (14 days) 8.648 g/kg soil dw [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial plants

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to birds

Data not provided by the registrant

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 2 summaries submitted
  • 2 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DMEL) 320 ng/m³ carcinogenicity
Acute /short term: (Low hazard (no threshold derived)) -
Local Effects
Long-term: Hazard unknown (no further information necessary as no exposure expected)
Acute /short term: Hazard unknown (no further information necessary as no exposure expected)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DMEL) 100 ng/kg bw/day carcinogenicity
Acute /short term: (Medium hazard (no threshold derived)) -
Local Effects
Long-term: (High hazard (no threshold derived)) -
Acute /short term: (High hazard (no threshold derived)) -
EYE Exposure
High hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: Hazard unknown (no further information necessary as no exposure expected)
Acute /short term: Hazard unknown (no further information necessary as no exposure expected)
Local Effects
Long-term: Hazard unknown (no further information necessary as no exposure expected)
Acute /short term: Hazard unknown (no further information necessary as no exposure expected)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: Hazard unknown (no further information necessary as no exposure expected)
Acute /short term: Hazard unknown (no further information necessary as no exposure expected)
Local Effects
Long-term: Hazard unknown (no further information necessary as no exposure expected)
Acute /short term: Hazard unknown (no further information necessary as no exposure expected)
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: Hazard unknown (no further information necessary as no exposure expected)
Acute /short term: Hazard unknown (no further information necessary as no exposure expected)
EYE Exposure
Hazard unknown (no further information necessary as no exposure expected)

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation potential:
No bioaccumulation potential

Acute toxicity

Study results
oral
  • 10 studies submitted
  • 3 studies processed
P/RResults
LD50 100 - 200 mg/kg bw (rat) [3]
M/CInterpretations of results
Category 3 based on GHS criteria [1]

Type of Study provided
oral
Studies with data
Key study 3
Supporting study 5 1 1
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 2 studies submitted
  • 2 studies processed
P/RResults
LC0 (6 h) 1.3 mg/L air (rat) [2]
LC100 (6 h) 2.14 mg/L air (rat) [2]
M/CInterpretations of results
Category 4 based on GHS criteria [1]

inhalation
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 7 studies submitted
  • 3 studies processed
P/RResults
LD50 700 - 1 400 mg/kg bw (guinea pig) [2]
M/CInterpretations of results
Category 3 based on GHS criteria [1]

dermal
Studies with data
Key study
Supporting study
Weight of evidence 6
Other 1
Data waiving
no waivers
other routes
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

other routes
Studies with data
Key study 1
Supporting study
Weight of evidence 2
Other
Data waiving
no waivers
M/C Summaries
  • 3 summaries submitted
  • 2 summaries processed
Oral route:
Adverse effect observed LD50 100 mg/kg bw
Inhalation route:
Adverse effect observed LC50 1.7 mg/L air
Dermal route:
Adverse effect observed LD50 660 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 10 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 3 1
Supporting study 6
Weight of evidence
Other
Data waiving
no waivers
Study data: eye
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 2 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 3 summaries submitted
  • 2 summaries processed
Skin
Adverse effect observed (irritating)
Eye
Adverse effect observed (irreversible damage)
Respiratory
No study available

Sensitisation

Study results
Study data: skin
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 2 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 3 summaries submitted
  • 2 summaries processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Study data: oral
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 3
Exposure cons.
Other
Study data: inhalation
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: inhalation
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: dermal
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Genetic toxicity

Study results
Study data: in vitro
  • 12 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 7
Supporting study 4 1
Weight of evidence
Other
Data waiving
no waivers
Study data: in vivo
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 3 summaries submitted
  • 1 summary processed
Toxicity - InVitro
Adverse effect observed (positive)
Toxicity - InVivo
Adverse effect observed (positive)

Carcinogenicity

Study results
  • 14 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 3
Supporting study 10 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: developmental
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 3
Exposure cons.
Other
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant