Brief Profile

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
201-069-1
CAS no.:
77-92-9
Index number:
Molecular formula:
C6H8O7
SMILES:
OC(=O)CC(O)(CC(O)=O)C(O)=O
InChI:
InChI=1S/C6H8O7/c7-3(8)1-6(13,5(11)12)2-4(9)10/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
Type of substance:
Mono constituent substance
Origin:
Organic
Registered compositions:
45
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Warning! According to the classification provided by companies to ECHA in REACH registrations this substance causes serious eye irritation and may cause respiratory irritation.

Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance causes serious eye damage and causes skin irritation.

Breakdown of all 4274 C&L notifications submitted to ECHA

Eye Irrit. 2 H319
STOT SE 3 H335
Skin Irrit. 2 H315
Not Classified
Eye Dam. 1 H318
Skin Corr. 1B H314
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 108 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
Seveso Annex I:
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
This substance is approved for use as a Biocidal Active Substance
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 000 tonnes per annum.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is approved for use as a biocide in the EEA and/or Switzerland, for: disinfection.

This substance is approved in the EEA and/or Switzerland for use in biocidal products more favourable for the environment, human or animal health.

This substance is used in the following products: washing & cleaning products, cosmetics and personal care products and air care products.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

This substance is used in the following activities or processes at workplace: the low energy manipulation of substances bound in materials or articles, high energy work-up of substances bound in materials or articles (e.g. hot rolling/forming, grinding, mechanical cutting, drilling or sanding), production of mixtures or articles by tabletting, compression, extrusion or pelletisation and potentially closed industrial processing with minerals/metals at elevated temperature (e.g. smelters, furnaces, refineries, coke ovens).

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints) and outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)).

This substance can be found in products with material based on: paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper), stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material) and wood (e.g. floors, furniture, toys). This substance is intended to be released from scented: paper products.

This substance is used in the following products: washing & cleaning products, polishes and waxes, coating products and fillers, putties, plasters, modelling clay.

This substance is used in the following areas: building & construction work, health services, agriculture, forestry and fishing, mining and formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: furniture and machinery and vehicles.

This substance is used in the following activities or processes at workplace: transfer of chemicals, roller or brushing applications, non-industrial spraying and hand mixing with intimate contact only with personal protective equipment available.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

This substance is used in the following products: polishes and waxes, washing & cleaning products, fertilisers and air care products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, mixing in open batch processes, transfer of substance into small containers and closed batch processing in synthesis or formulation.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, formulation in materials and in processing aids at industrial sites.

This substance is used in the following products: pH regulators and water treatment products and washing & cleaning products.

This substance is used in the following areas: mining and health services. This substance is used for the manufacture of: machinery and vehicles, chemicals and fabricated metal products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, roller or brushing applications and treatment of articles by dipping and pouring.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites and of substances in closed systems with minimal release. Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed, continuous processes with occasional controlled exposure and closed batch processing in synthesis or formulation.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, formulation of mixtures, formulation in materials and in processing aids at industrial sites.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: wash parts of the body (as specified by manufacturer/supplier)in contact with substance thoroughly after handling; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier; avoid breathing the dust, fume, gas, mist, vapours or spray.

Response statements

In case of incident: Call a poison center or doctor/physician if you feel unwell. If in eyes: rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing. If eye irritation persists get medical advice/attention.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • 5N Plus Lübeck GmbH, Kaninchenborn 24-28 23560 Luebeck Germany
  • A.S. Watson (Health & Beauty Continental Europe) B.V., Evora, Postbus 34, 3927 Zl Renswoude Netherlands
  • A.S. Watson (Health & Beauty Ireland) Limited, 70 Sir John Rogerson’s Quay D02 Dublin 2 Ireland
  • Abbott Diagnostics GmbH, Max Planck Ring 2 D-65205 Delkenheim Hessen Germany
  • Access Business Group International BV, Celsiusweg 20 Industrial Estate 4212 5928 PR Venlo Netherlands
  • ADM Services B.V., Kingsfordweg 83 1043 GP Amsterdam Netherlands
  • Advanced Refining Technologies GmbH, In der Hollerhecke 1 67547 Worms Germany
  • AgroFresh Holding France SAS, 23-25 Avenue Mac-Mahon 75017 Paris France
  • ALFARIN QUIMICA, S.A., C/. Ibiza 35 -5º C 28009 MADRID Spain
  • ARCHROMA IBÉRICA, S.L., ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain
  • Asahi Chemical Europe s.r.o., Lužná 716/2 16000 Praha 6 - Vokovice Praha Czech Republic
  • Ashland Services BV (0311), Noordweg 9 3336 LH Zwijndrecht Netherlands
  • Atlantic Chemicals Trading GmbH, Hermannstr. 46 20095 Hamburg Germany
  • Avantor Performance Materials Poland S.A., Sowińskiego 11 44-100 Gliwice Poland
  • B-Lands Consulting (811232-9), World Trade Center, 5 Place Robert Schuman - BP 1510 38025 Grenoble France France
  • B-Lands Consulting (811506-9), World Trade Center, 5 Place Robert Schuman, BP 1516 38025 Grenoble France France
  • B-Lands Consulting (811508-5), World Trade Center, 5 Place Robert Schuman, BP 1516 38025 Grenoble France France
  • B-Lands Consulting (811509-8), World Trade Center, 5 Place Robert Schuman, BP 1516 38025 Grenoble France France
  • B-Lands Consulting (811512-8), World Trade Center, 5 Place Robert Schuman, BP 1516 38025 Grenoble France France
  • B-Lands Consulting (811527-4), World Trade Center, 5 Place Robert Schuman, BP 1516 38025 Grenoble France France
  • B-Lands Consulting (811547-6), World Trade Center, 5 Place Robert Schuman, BP 1516 38025 Grenoble France France
  • BASF Espanola S.L., Calle Can Ràbia, n. 3-5 8017 Barcelona Spain
  • BASF Health and Care Products France S.A.S., 49, Avenue Georges Pompidou 92593 Levallois-Perret Cedex France
  • BASF Italia S.p.A., Via Marconato 8 20811 Cesano Maderno Italy
  • BASF Personal Care and Nutrition GmbH, Henkelstr. 67 40589 Düsseldorf Germany
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • BBCA BELGIUM N.V., Hoeikensstraat 2 B -2830 Willebroek Antwerp Belgium
  • Beckman Coulter France SAS, 130, Avenue de Lattre de Tassigny 13009 Marseille France
  • Brenntag GmbH, Messeallee 11 45131 Essen Germany
  • BÜFA Chemikalien GmbH & Co. KG, An der Autobahn 14 27798 Hude / Altmoorhausen Germany
  • C.S.B. GmbH, Düsseldorfer Str. 113 47809 Krefeld Germany
  • Card Factory Ireland Ltd, c/o Unit 10 Killegland Walk A84 HF78 Ashbourne Co. Meath Ireland
  • Cargill B.V., Evert van de Beekstraat 378 1118 CZ Amsterdam Schiphol North Holland Netherlands
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • Chemours Netherlands B.V., Baanhoekweg 22 3313 LA Dordrecht Netherlands
  • Chemservice GmbH - (Q1Z2), Herrnsheimer Hauptstrasse 1b 67550 Worms Germany
  • CIMACHEM GmbH, Kupferbergstr. 59 67292 Kirchheimbolanden Germany
  • Clariant Produkte (Deutschland) GmbH, Am Unisys-Park 1 65843 Sulzbach am Taunus Germany
  • Colgate-Palmolive Services (Poland) sp. z o.o. / OR Guatemala, ul. Tasmowa 7 02-677 Warsaw Poland
  • Corteva Agriscience France S.A.S., Immeuble Equinoxe 2 1bis avenue du 8 Mai 1945 78280 Guyancourt France
  • Corteva Agriscience Italia S.r.l., via dei Comizi Agrari 10 26100 Cremona (CR) Italy
  • D&F b.v., Newtonweg 6 4104 BK Culemborg Netherlands
  • DAABON Europa GmbH, Nettegasse 80 50259 Pulheim Germany
  • De Sangosse (Ireland) Limited, 1 CASTLEWOOD AVENUE RATHMINES D06 H685 DUBLIN Ireland
  • DEKRA Assurance Services GmbH OR07, Handwerkstr. 15 70565 Stuttgart Germany
  • DEKRA Assurance Services GmbH OR10, Handwerkstraße 15 70565 Stuttgart Germany
  • Donauchem GmbH, Lisztstraße 4 1037 Vienna Vienna Austria
  • DOW AGROSCIENCES B.V. (BE), Rue Montoyer 25, 1000 Brussels Belgium
  • Dow Belgium B.V.B.A., Grotesteenweg 214 B-2600 Antwerpen (Berchem) Belgium Belgium
  • DOW BENELUX B.V., Postbus 48 4530 AA Terneuzen Netherlands
  • Du Pont de Nemours (Deutschland) GmbH, Hugenottenallee 175 D-63263 Neu-Isenburg Hesse Germany
  • DuPont Solutions (France) SAS, Equinoxe 2 1bis avenue du 8 Mai 1945 78280 Guyancour France
  • Ecolab Production Belgium B.V.B.A., Havenlaan 4 3980 Tessenderlo Belgium
  • Evonik Operations GmbH, Rellinghauser Straße 1-11 45128 Essen Germany
  • ExponentOR70I, Block 1, Blanchardstown Corporate Park Ballycoolen Road, Blanchardstown D15 AKK1 Dublin Ireland
  • ExponentOR73I, Block 1, Blanchardstown Corporate Park Ballycoolen Road Blanchardstown D15 AKK1 Dublin Ireland
  • Gadot Bio-Chem (Europe) BV, 41 Hoefsmidstraat 3194AA Hoogvliet Netherlands
  • Gadot Bio-Chem (Europe) BV, Hoefsmidstraat 41 3194 AA Hoogvliet Netherlands
  • Genencor International B.V. - OR-US, Willem Einthovenstraat 4 2342 BH Oegstgeest Netherlands
  • Global Product Compliance (Europe) AB, IDEON, Beta 5, Scheelevägen 17 223 63 Lund Sweden
  • Gojo Luxembourg S.à r.l., 1 rue jean piret L-2350 Luxembourg Luxembourg
  • GRACE GmbH, In der Hollerhecke 1 67545 Worms Germany
  • Grillo-Werke AG, Weseler Straße 1 47169 Duisburg Germany
  • H.B. S.R.L., via vespucci 7 36071 ARZIGNANO VICENZA Italy
  • HACH LANGE GMBH, Koenigsweg 10 14163 Berlin Germany
  • Hall & Associates (Marketing) N I Ltd, 142a Saintfield Road BT27 6UH Lisburn County Down United Kingdom (Northern Ireland)
  • HFC Prestige Manufacturing Germany GmbH, Berliner Allee 65 64295 Darmstadt Germany
  • Honeywell Belgium NV, Gaston Geenslaan 14 3001 Heverlee Belgium Belgium
  • Huntsman Textile Effects (Germany) GmbH, Rehlinger Str. 1 D-86462 Langweid a.Lech Germany
  • Imerys Minerals International Sales, PLACE DE PARIS 2 LUXEMBOURG 2314 luxembourg Luxembourg (Grand-Duché) Luxembourg
  • Intertek Deutschland GmbH CGDN, Stangenstr.1 70771 Leinfelden-Echterdingen Germany
  • Jungbunzlauer Austria AG, Factory Pernhofen 2064 Wulzeshofen Austria
  • Jungbunzlauer Ladenburg GmbH, Dr. Albert-Reimann-Strasse 18 68526 Ladenburg Germany
  • Koopman International B.V., Distelweg 88 1031 HH Amsterdam Netherlands
  • LinmarkOR91, Linmark Consulting Ltd Hillock, Ballut Street STJ 1373 St Julian's Malta
  • Merck KGaA, Frankfurter Strasse 250 64293 Darmstadt Germany
  • Oskar Berg Basischemikalien GmbH, Kardinal-Galen-Str. 56 47051 Duisburg Germany
  • PRODUCTOS CAPILARES L'OREAL S.A., Calle Lopez Bravo n°78 Poligono Industrial Villalonquéjar 09001 BURGOS Spain
  • REACh ChemConsult GmbH, Strehlener Str. 14 01069 Dresden Germany
  • REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland
  • REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland
  • REACHLaw Ltd., Vänrikinkuja 3 JK 21 02600 Espoo Finland
  • RFI Food Ingredients Handelsgesellschaft mbH, Kennedydamm 24 40476 Duesseldorf NRW Germany
  • RHI Magnesita GmbH, Kranichberggasse 6 1120 Vienna Austria
  • Rossmann SDP Sp. z o.o., ul.Św.Teresy 109 91-222 Łódź Łódź Poland
  • Rotam Crop Protection Europe SAS, 75 cours Albert Thomas-6e avenue/Batiment D 69003 Lyon France
  • S.A. CITRIQUE BELGE N.V., Pastorijstraat 249 3300 TIENEN Belgium
  • SHELL CATALYSTS & TECHNOLOGIES BELGIUM, Pantserschipstraat 331 9000 Gent Belgium
  • Siemens Healthcare Diagnostics Products GmbH, Emil-von-Behring-Str. 76 35041 Marburg Germany
  • SIGMA-ALDRICH CHEMIE GMBH, Riedstrasse 2 89555 Steinheim Germany
  • Sigma-Aldrich Ireland Ltd, Vale Road . Arklow Co. Wicklow Ireland
  • Soapland GmbH & Co. OHG, Am weißen Haus 1 56626 Andernach Germany
  • Sodasan GmbH, Rudolf-Diesel-Str.19 26670 Uplengen-Jübberde Germany
  • Solberg Industri AS, Trippeveien 4 1618 FREDRIKSTAD Norway
  • Specialty Electronic Materials Netherlands BV OR-1, Baanhoekweg 22 3313 LA Dordrecht Netherlands
  • STERIS Ireland Limited, IDA Business and Technology Park Country Offialy R35 X865 Tullamore Ireland
  • STOCKMEIER QUIMICA, S.L., Avda. Baix Llobregat,3 Portal 5 08970 Sant Joan Despí Barcelona Spain
  • Tate&Lyle slovakia s.r.o.-3, Boleráz 114 91908 Boleráz Slovakia
  • Tate&Lyle Slovakia s.r.o.-6, Boleráz 114 91908 Boleráz Slovakia
  • TFL Ledertechnik GmbH, Peter-Krauseneck-Strasse 16 79618 Rheinfelden Germany
  • TIGI Haircare GmbH, Hertzstraße 6 71083 Herrenberg Germany
  • TSGE_2019-021, Im Fliegerhorst 12 38642 Goslar Germany
  • Versum Materials Netherlands B.V., Haarlerbergweg 21-23, 3e etage 1101CH Amsterdam Netherlands
  • WSP Deutschland A.G. (OR12), Dingolfinger Straße 1-15 81673 Munchen Germany
  • [Confidential], [Confidential]
  • B-Lands Consulting (811535-9), World Trade Center, 5 Place Robert Schuman, BP 1516 38025 Grenoble France France
  • B-Lands Consulting (811619-6), World Trade Center, 5 Place Robert Schuman - BP 1516 38025 Grenoble France France
  • B-Lands Consulting (811739-5), Central Chambers 45-47 Albert Street CV21 2SG Warwickshire Rugby United Kingdom
  • B-Lands Consulting (811740-9), Central Chambers 45-47 Albert Street CV21 2SG Warwickshire Rugby United Kingdom
  • Corteva Agriscience UK Limited, CPC2 Capital Park, Fulbourn Cambridge CB21 5XE Cambridgeshire United Kingdom
  • Du Pont (U.K.) Limited, London Road 4th Floor, Kings Court SG1 2NG Stevenage Hertfordshire United Kingdom
  • Interplay UK Ltd, Interplay UK Ltd Unit D, Meter House, Fieldhouse Lane, SL7 1LW Marlow Bucks United Kingdom
  • Nortem Chem, SA, C/ Alexander Humboldt, 12 P.I. Salinas de Poniente 11500 El Puerto de Santa Maria Spain
  • Nutrition & Biosciences Netherlands B.V. OR_CH, Willem Einthovenstraat 4 2342 BH Oegstgeest Netherlands
  • Sigma-Aldrich Company Limited, The Old Brickyard, New Road SP8 4XT Gillingham United Kingdom
  • Specialty Electronic Materials Netherlands BV, Baanhoekweg 22 3313 LA Dordrecht Netherlands
  • TJ Morris Ltd, 50 Bedford Street BT2 7FW Belfast United Kingdom (Northern Ireland)

Substance names and other identifiers

1,2,3-Propanetricarboxylic acid, 2-hydroxy-
Other
2-Hydroxy-1,2,3-propanetricarboxylic acid
Other
2-Hydroxypropanetricarboxylic acid
Other
2-Hydroxytricarballylic acid
Other
3-Carboxy-3-hydroxypentane-1,5-dioic acid
Other
Aciletten
Other
Anhydrous citric acid
Other
Chemfill
Other
Citretten
Other
Citric acid
EC Inventory, REACH pre-registration, Other, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, FCM and Articles Regulation, Annex I - Authorised Substances, General Product Safety Directive - Hazardous Substances, FCMs Recycled Plastic & Articles Regulation - Annex I - Authorised Use, Food Contact Regenerated Cellulose Directive - Authorised Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties
Citric acid
Biocidal active substances, REACH pre-registration, Other, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, FCM and Articles Regulation, Annex I - Authorised Substances, General Product Safety Directive - Hazardous Substances, FCMs Recycled Plastic & Articles Regulation - Annex I - Authorised Use, Food Contact Regenerated Cellulose Directive - Authorised Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties
Citric acid, anhydrous
Other
Citro
Other
Hydrocerol A
Other
Kyselina 2-hydroxy-1,2,3-propantrikarbonova
Other
Kyselina citronova
Other
Acid citric (ro)
Biocidal active substances
Acide citrique (fr)
Biocidal active substances
Acido citrico (it)
Biocidal active substances
Aċidu ċitriku (mt)
Biocidal active substances
Citric acid (no)
Biocidal active substances
Citrinų rūgštis (lt)
Biocidal active substances
Citroenzuur (nl)
Biocidal active substances
Citromsav (hu)
Biocidal active substances
Citronensäure (de)
Biocidal active substances
Citronska kislina (sl)
Biocidal active substances
Citronskābe (lv)
Biocidal active substances
Citronsyra (sv)
Biocidal active substances
citronsyre (da)
Biocidal active substances
Kwas cytrynowy (pl)
Biocidal active substances
kyselina citronová (cs)
Biocidal active substances
kyselina citrónová (sk)
Biocidal active substances
Limunska kiselina (hr)
Biocidal active substances
Sidrunhape (et)
Biocidal active substances
Sitruunahappo (fi)
Biocidal active substances
Ácido cítrico (es)
Biocidal active substances
Ácido cítrico (pt)
Biocidal active substances
Κιτρικό οξύ (el)
Biocidal active substances
Лимонена киселина (bg)
Biocidal active substances
1,2,3-Propanetricarboxylic acid, 2-hydroxy-
Other
1,2,3-Propanetricarboxylic acid, 2-hydroxy-
C&L Inventory
1,2,3-Propanetricarboxylic acid, 2-hydroxy-
Registration dossier
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, monohydrate
C&L Inventory
2-hydorxypropane-1,2,3-tricarboxylic acid
C&L Inventory
2-hydroxy -1,2,3 propane tricarboxylic acid
C&L Inventory
2-hydroxy-1,2,3-propane tricarboxylic acid
C&L Inventory
2-HYDROXY-1,2,3-PROPANETRICARBOXYLIC ACID
C&L Inventory, Registration dossier
2-hydroxy-1,2,3-propanetricarboxylic acid monohydrate
C&L Inventory
2-Hydroxypropan-1,2,3-tricarbonsäure
C&L Inventory
2-HYDROXYPROPANE-1, 2, 3-TRICARBOXYLIC ACID
Registration dossier
2-hydroxypropane-1,2,3-tricarboxylic
C&L Inventory
2-hydroxypropane-1,2,3-tricarboxylic ...
C&L Inventory
2-Hydroxypropane-1,2,3-tricarboxylic acid
C&L Inventory, Registration dossier, Other
2-hydroxypropane-1,2,3-tricarboxylic acid anhydrous
C&L Inventory
2-hydroxypropane-1,2,3-tricarboxylic acid hydrate
C&L Inventory
2-Hydroxypropane-1,2,3-tricarboxylic acid, Hydroxytricarballylic acid
Registration dossier
2-hydroxypropane-1,2,3-tricarboxylic acid.
C&L Inventory
2-hydroxypropane-1,2,3-trioic acid
C&L Inventory
2-hydroxypropane-l,2,3-tricarboxylic acid
C&L Inventory
2-hydroxypropane.1,2,3-tricaboxylic
C&L Inventory
3-carbossi-3-idrossi-1,5-pentandioic acid
C&L Inventory
3-carboxy-3-hydroxy pentanedioic acid
C&L Inventory
3-Carboxy-3-hydroxypentanedioic acid
C&L Inventory
3-hydroxy-1,2,3-propanetricarboxylic acid, anhydrous
C&L Inventory
3-hydroxy-3-carboxy-1,5-pentanedioic acid
Registration dossier
3-hydroxy-3-carboxy-1,5-pentanedioic acid.
Registration dossier
3-hydroxy-3-carboxy-1,5-pentaneioicacid
Registration dossier
Acide citrique
C&L Inventory
acido 2-idrossi-1,2,3-propantricarbossilico monoidrato
C&L Inventory
acido 3-carbossi-3-idrossi-1,5-pentandioico
C&L Inventory
acido citrico anidro
C&L Inventory
Anhydrous Citric Acid
Registration dossier
Anhydrous form: 2-hydroxypropane-1,2,3-tricarboxylic acidMonohydrated form: 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, monohydrate
C&L Inventory
CITRIC ACID
C&L Inventory, Registration dossier
Citric Acid
C&L Inventory, Registration dossier
CITRIC ACID ANHYDROUS
C&L Inventory
CITRIC ACID MONOHYDRATE
C&L Inventory
CITRIC ACID MONOHYDRATE
C&L Inventory, Registration dossier
CITRIC ACID, MONOHYDRATE
Registration dossier
citric acid; 3-hydroxy-3-carboxy-1,5-pentanedioic acid;
Registration dossier
citric acid 
C&L Inventory
CITROMSAV-MONOHIDRÁT
C&L Inventory
Citronensäure, wasserfrei
C&L Inventory
hydroxypropene - 1,2,3 - tricarboxylic
C&L Inventory
ORGANIC ACID
C&L Inventory
Acide citrique
Registration dossier
Acide citriqueACIDO CITRICO MONOIDRATOCITRIC ACIDCitric Acid AnhydrousCitric Acid MonohydrateCitronensäure-MonohydratÁcido citrico
Registration dossier
ACIDO CITRICO MONOIDRATO
C&L Inventory, Registration dossier
CITRIC ACID
C&L Inventory, Registration dossier
Citric Acid Anhydrous
Registration dossier
CITRIC ACID MONOHYDRATE
Registration dossier
Citronensäure-Monohydrat
Registration dossier
Ácido citrico
Registration dossier
1192555-95-5
CAS number
Other
1192555-95-5
Deleted CAS number
Other
12262-73-6
CAS number
Other
12262-73-6
Deleted CAS number
Other
136108-93-5
CAS number
Other
136108-93-5
Deleted CAS number
Other
2023788-69-2
CAS number
Other
2023788-69-2
Deleted CAS number
Other
245654-34-6
CAS number
Other
245654-34-6
Deleted CAS number
Other
43136-35-2
CAS number
Other
43136-35-2
Deleted CAS number
Other
5949-29-1
CAS number
C&L Inventory
623158-96-3
CAS number
Other
623158-96-3
Deleted CAS number
Other
77-92-9
CAS number
EC Inventory, C&L Inventory, Biocidal active substances, Registration dossier, REACH pre-registration, Other, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, FCM and Articles Regulation, Annex I - Authorised Substances, General Product Safety Directive - Hazardous Substances, FCMs Recycled Plastic & Articles Regulation - Annex I - Authorised Use, Food Contact Regenerated Cellulose Directive - Authorised Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties
856568-15-5
CAS number
Other
856568-15-5
Deleted CAS number
Other
878903-72-1
CAS number
Other
878903-72-1
Deleted CAS number
Other
890704-54-8
CAS number
Other
890704-54-8
Deleted CAS number
Other
896506-46-0
CAS number
Other
896506-46-0
Deleted CAS number
Other
906507-37-7
CAS number
Other
906507-37-7
Deleted CAS number
Other

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 1 study submitted
  • 1 study processed
C Physical state at 20°C and 1013 hPa
Solid (100%) [1]
C Form
Crystalline (100%) [1]
C Odour
Odourless (100%) [1]
C Substance type
Organic (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Solid (100%)
Form
Solid: crystalline (100%)

Melting/freezing point

Study results
  • 2 studies submitted
  • 1 study processed
R Melting / freezing point
153 °C @ 101.3 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
153 °C

Boiling point

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Density

Study results
  • 2 studies submitted
  • 1 study processed
R Relative density
1.665 @ 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
1.665

Vapour pressure

Study results
  • 1 study submitted
  • 1 study processed
R Vapour pressure
0 Pa @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
0 Pa @ 25 °C

Partition coefficient

Study results
  • 5 studies submitted
  • 1 study processed
R Log Pow
-1.8 - -1.55 [3]

Type of Study provided
Studies with data
Key study 1
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Log Kow (Log Pow)
-1.6

Water solubility

Study results
  • 8 studies submitted
  • 1 study processed
R Water solubility (mass/vol.)
84 - 814 g/L @ 10 - 100 °C [10]

Type of Study provided
Studies with data
Key study 1
Supporting study 6
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
R Summaries
  • 1 summary submitted
  • 1 summary processed
Water solubility
592 g/L @ 20 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Auto flammability

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 5 studies submitted
  • 1 study processed
C Interpretation of results
Not classified based on GHS criteria (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Not classified (100%)

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
Non oxidising (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers

No summary exists for this scientific endpoint

Dissociation constant

Study results
  • 2 studies submitted
  • 1 study processed
C Dissociating properties
Yes (100%) [1]
R Dissociation constant
3.13 - 6.4 @ 25 °C [3]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Half life in air
52.8 h
Degradation rate constant with OH radicals
0 cm³ molecule-1 d-1

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in soil

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water - screening tests

Study results
  • 5 studies submitted
  • 3 studies processed
C Interpretation of results
Readily biodegradable (67%), Inherently biodegradable (33%) [3]

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence 3
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Biodegradation in water
Readily biodegradable (100%)
Type of water
Freshwater (100%)

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Adsorption/desorption

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Henry's law constant
0 Pa.m³.mol-1 @ 25 °C

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater No hazard identified (1)
Intermittent releases (freshwater) No hazard identified (1)
Marine water No hazard identified (1)
Intermittent releases (marine water) No hazard identified (1)
Sewage treatment plant (STP) No hazard identified (1)
Sediment (freshwater) No hazard identified (1)
Sediment (marine water) No hazard identified (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil No hazard identified (1)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (1)

Short–term toxicity to fish

Study results
  • 5 studies submitted
  • 2 studies processed
P/RResults
LC50 (4 days) 100 mg/L [1]
LC50 (48 h) 440 - 760 mg/L [2]
LC0 (48 h) 200 - 620 mg/L [2]
LC100 (4 days) 1 g/L [1]
LC100 (48 h) 600 - 800 mg/L [2]

Type of Study provided
Studies with data
Key study
Supporting study 2 1
Weight of evidence 2
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 6 studies submitted
  • 2 studies processed
P/RResults
EC50 (48 h) 50 mg/L [1]
LC50 (24 h) 1.535 g/L [1]
LC0 (24 h) 1.206 g/L [1]
LC100 (24 h) 2.083 g/L [1]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 5
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 3 studies submitted
  • 1 study processed
P/RResults
NOEC (8 days) 425 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC10 or NOEC for freshwater algae
425 mg/L

Toxicity to aquatic plants other than algae

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to microorganisms

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial plants

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to birds

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to mammals

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: Low hazard (no threshold derived)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
Low hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: Low hazard (no threshold derived)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
Low hazard (no threshold derived)

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Acute toxicity

Study results
oral
  • 2 studies submitted
  • 1 study processed
P/RResults
LD50 5 400 mg/kg bw (mouse) [1]
M/CInterpretations of results
GHS criteria not met [1]

Type of Study provided
oral
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

inhalation
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
dermal
  • 1 study submitted
  • 1 study processed
P/RResults
LD50 2 000 mg/kg bw (rat) [1]
M/CInterpretations of results
GHS criteria not met [1]

dermal
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

other routes
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
No adverse effect observed LD50 5 400 mg/kg bw
Dermal route:
No adverse effect observed LD50 2 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
No adverse effect observed (not irritating)
Eye
Adverse effect observed (irritating)
Respiratory
Adverse effect observed (irritating)

Sensitisation

Study results
Study data: skin
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 5 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Study data: oral
Studies with data
Key study
Supporting study 3 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: inhalation
  • 0 studies submitted
  • 0 studies processed

No data available

Study data: inhalation
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 0 studies submitted
  • 0 studies processed

No data available

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Genetic toxicity

Study results
Study data: in vitro
  • 7 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 2
Supporting study 3
Weight of evidence 1
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: in vivo
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Toxicity - InVitro
Adverse effect observed (positive)
Toxicity - InVivo
No adverse effect observed (negative)

Carcinogenicity

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study
Supporting study 2 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: developmental
  • 7 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study
Supporting study 4 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant