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Previous Testing Proposals

Previous Testing Proposals

Previous Testing Proposals

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

 

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Page 1 of 10
200 Items per Page
Showing 1 - 200 of 1,996 results.
Name
EC Number
CAS Number
Hazard endpoint for which vertebrate testing was proposed
Date of publication to call for available information
Deadline for submitting information
Alternatives to vertebrate testing
 
Silicon 231-130-8 7440-21-3 Subchronic toxicity (90 day): inhalation 14/02/2011 31/03/2011 Details
Tetraethyllead 201-075-4 78-00-2 Sub-chronic toxicity study (90-day) 01/07/2011 15/08/2011 Details
Fatty acids, tall-oil, compds. with diethanolamine 263-157-6 61790-66-7 Sub-chronic toxicity (90-day): oral||Note: testing proposed with Amides, C8-18 (even numbered) and C18-unsatd., N-(2-hydroxypropyl)  (EC no. 931-329-6) 03/05/2023 19/06/2023 Details
methylsilanetriyl triacetate 224-221-9 4253-34-3 Sub-chronic toxicity (90-day): oral||Note: testing proposed with [triethoxy(methyl)silane] (CAS no. 2031-67-6) 03/10/2023 17/11/2023 Details
3-{[3-(C10-16-oxy)propyl]amino}propan-1-aminium acetate 941-152-6 - Sub-chronic toxicity (90-day): oral||Note: testing proposed with 1,3-propanediamine, N-[3-((C11-14, C13-rich)oxy)propyl]-branched acetate (EC: 931-295-2) 15/07/2022 29/08/2022 Details
N-{3-[C12-14-(even numbered)-alkyloxy]propyl}propane-1,3-diamine 701-437-6 - Sub-chronic toxicity (90-day): oral|| Note: testing proposed with [1,3-propanediamine, N-[3-((C11-14, C13-rich)oxy)propyl]-branched acetate (EC no 931-295-2) 15/07/2022 29/08/2022 Details
4-tert-butylcyclohexyl acetate 250-954-9 32210-23-4 Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with cis-4-tert-butylcyclohexyl acetate 		24/02/2020 09/04/2020 Details
Tetramethylammonium hydroxide 200-882-9 75-59-2 Sub-chronic toxicity (90-day): oral
// Note: testing proposed with Tetramethylammonium chloride (EC 200-880-8)
|| Note: Link to justification in the registration dossier not given as the information is confidential 		27/01/2020 12/03/2020 Details
2,4,6,8-tetramethylcyclotetrasiloxane 219-137-4 2370-88-9
Sub-chronic toxicity (90-day): oral
-
22/11/2017
22/11/2017
08/01/2018
08/01/2017
 Details
(Z)-4-[C11-13(branched)alkylamino]-4-oxo-2-butenoic acid 701-116-0 84583-68-6 Sub-chronic toxicity (90-day): oral || Note: The previous EC number for the substance is 283-219-6. 22/06/2017 07/08/2017 Details
Octadecanoic acid, sulfonated, potassium salt 701-179-4 - Sub-chronic toxicity (90-day): oral || Note: The List number has changed. 31/01/2018 19/03/2018 Details
octyltrichlorosilane 226-112-1 5283-66-9 Sub-chronic toxicity (90-day): oral || Note: testing proposed with triethoxy(2,4,4-trimethylpentyl)silane (EC 252-558-1, CAS 35435-21-3) 25/06/2015 10/08/2015 Details
trimethoxyoctylsilane 221-338-7 3069-40-7 Sub-chronic toxicity (90-day): oral || Note: testing proposed with triethoxy(2,4,4-trimethylpentyl)silane (CAS 35435-21-3) 07/08/2015 22/09/2015 Details
Reaction mass of 4,4,13,13-tetraethoxy-3,14-dioxa-8,9-dithia-4,13-disilahexadecane and 4,4,14,14-tetraethoxy-3,15-dioxa-8,9,10-trithia-4,14-disilaheptadecane 915-748-1 - Sub-chronic toxicity (90-day): oral || Note: testing proposed with polysulfides, bis[3-(triethyoxysilyl)propyl (CAS No 211519-85-6) 25/05/2020 09/07/2020 Details
tetraethylammonium hydroxide 201-073-3 77-98-5 Sub-chronic toxicity (90-day): oral || Note: testing proposed with N,N,N-trimethylmethanaminium chloride (EC 200-880-8; CAS 75-57-0) 30/09/2015 16/11/2015 Details
2-Propyn-1-ol, reaction product with 1-2.5 moles of oxirane 941-793-1 - Sub-chronic toxicity (90-day): oral || Note: testing proposed with 2-Propyn-1-ol, compd. with methyloxirane (EC 609-530-2, CAS 38172-91-7) 17/04/2015 04/06/2015 Details
branched-nonyl 3,5,5 trimethylhexanoate 701-133-3 - Sub-chronic toxicity (90-day): oral || Note: previous EC no 609-993-0 21/05/2018 05/07/2018 Details
N,N''-propane-1,3-diylbis[N'-octadecylurea 252-667-4 35674-65-8 Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity) 29/03/2016 13/05/2016 Details
Resin acids and Rosin acids, hydrogenated, Me esters 232-476-2 8050-15-5 Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin, methyl ester (CAS RN 68186-14-1), Rosin, ethylene glycol ester (CAS RN 68512-65-2) and Rosin, triethylene glycol ester (CAS RN 8050-25-7) 02/07/2013 16/08/2013 Details
Resin acids and Rosin acids, esters with ethylene glycol 270-986-7 68512-65-2 Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin, ethylene glycol ester (CAS RN 68512-65-2) 02/07/2013 16/08/2013 Details
Resin acids and Rosin acids, reaction products with formaldehyde, potassium salt 295-855-1 92129-53-8 Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin (CAS RN 8050-09-7), Rosin, hydrogenated (CAS RN 65997-06-0), and Rosin, reaction products with formaldehyde (CAS RN 91081-53-7) 02/07/2013 16/08/2013 Details
Rosin, oligomers 500-163-2 65997-05-9 Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin (CAS RN 8050-09-7), Rosin, hydrogenated (CAS RN 65997-06-0), and Rosin, reaction products with formaldehyde (CAS RN 91081-53-7) 02/07/2013 16/08/2013 Details
Amines, C12-14-tert-alkyl, mixed sec-Bu and iso-Bu phosphates 306-227-4 96690-34-5 Sub-chronic toxicity (90-day): oral || Note: testing proposed with Amines, C11-14-branched alkyl, monohexyl and dihexyl phosphates (EC 279-632-6) || Note: Testing proposal is based on concern identified by the registrant. 23/11/2020 07/01/2021 Details
trimethoxy(2,4,4-trimethylpentyl)silane 251-995-5 34396-03-7 Sub-chronic toxicity (90-day): oral
Note: testing proposed with triethoxy(2,4,4-trimethylpentyl)silane (EC 252-558-1, CAS 35435-21-3) " 		25/06/2015 10/08/2015 Details
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11-17 and C17 unsatd. alkyl) derivs. and sodium hydroxide and 2-propenoic acid 946-533-0 - Sub-chronic toxicity (90-day): oral || Note: testing proposed with β-Alanine, N-(2-aminoethyl)-N-(2-hydroxyethyl)-, N-coco acyl derivs., monosodium salts (EC 298-632-7) 16/12/2020 01/02/2021 Details
Sodium 4(or 5)-methyl-1H-benzotriazolide 265-004-9 64665-57-2 Sub-chronic toxicity (90-day): oral || Note: testing proposed with Tolyltriazole (EC 249-596-6) 16/12/2020 01/02/2021 Details
(1-methylethylidene)di-4,1-phenylene tetraphenyl diphosphate,Bisphenol A Diphosphate,Bisphenol A Polyphosphate 425-220-8 5945-33-5 Sub-chronic toxicity (90-day): oral 01/09/2010 15/10/2010 Details
(3-chloropropyl)dimethoxymethylsilane 242-056-0 18171-19-2 Sub-chronic toxicity (90-day): oral 25/05/2020 09/07/2020 Details
(E)-7,11-dimethyl-3-methylenedodeca-1,6,10-triene 242-582-0 18794-84-8 Sub-chronic toxicity (90-day): oral 23/04/2018 07/06/2018 Details
1,2,4,5,7,8-Hexoxonane, 3,6,9-trimethyl-, 3,6,9-tris(Ethyl and Propyl) derivatives - - Sub-chronic toxicity (90-day): oral 30/06/2016 15/08/2016 Details
1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters 290-754-9 90218-76-1 Sub-chronic toxicity (90-day): oral 29/07/2011 12/09/2011 Details
1,2-diacetoxybut-3-ene 421-720-5 18085-02-4 Sub-chronic toxicity (90-day): oral 25/11/2021 10/01/2022 Details
1,3-diethyldiphenylurea 201-645-2 85-98-3 Sub-chronic toxicity (90-day): oral 03/03/2014 17/04/2014 Details
1,3-Propanediamine, N-[3-((C11-14, C13-rich)oxy)propyl]- branched acetate 931-295-2 - Sub-chronic toxicity (90-day): oral 25/05/2020 09/07/2020 Details
1-[bis[3-(dimethylamino)propyl]amino]propan-2-ol 266-587-2 67151-63-7 Sub-chronic toxicity (90-day): oral 21/03/2014 05/05/2014 Details
1-ethynylcyclohexanol 201-100-9 78-27-3 Sub-chronic toxicity (90-day): oral 18/02/2014 04/04/2014 Details
2,2'-[oxybis(methylene)]-bis[2-ethylpropane-1,3-diol] 245-509-0 23235-61-2 Sub-chronic toxicity (90-day): oral 30/09/2015 16/11/2015 Details
2,2'-ethylenedioxydiethyl bis(2-ethylhexanoate) 202-319-2 94-28-0 Sub-chronic toxicity (90-day): oral 26/01/2011 14/03/2011 Details
2,2'-oxybis[5,5-dimethyl-1,3,2-dioxaphosphorinane] 2,2'-disulphide 223-829-1 4090-51-1 Sub-chronic toxicity (90-day): oral 16/06/2022 01/08/2022 Details
2,2,6,6-tetramethyl-4-oxopiperidinooxy 220-778-7 2896-70-0 Sub-chronic toxicity (90-day): oral 03/04/2023 22/05/2023 Details
2,4-di-tert-butylphenol 202-532-0 96-76-4 Sub-chronic toxicity (90-day): oral 16/05/2011 30/06/2011 Details
2,5-di-tert-pentylhydroquinone 201-222-2 79-74-3 Sub-chronic toxicity (90-day): oral 31/05/2011 15/07/2011 Details
2,6-di-tert-butylphenol 204-884-0 128-39-2 Sub-chronic toxicity (90-day): oral 16/05/2011 30/06/2011 Details
2-[2,2-bis(2-prop-2-enoyloxyethoxymethyl)butoxy]ethyl 3-(dibutylamino)propanoate 701-363-4 - Sub-chronic toxicity (90-day): oral 26/08/2021 11/10/2021 Details
2-aminoethanol, monoester with boric acid 233-829-3 10377-81-8 Sub-chronic toxicity (90-day): oral 17/11/2011 02/01/2012 Details
2-Butenoic acid, 4-oxo-4-(tridecylamino)-, (Z)-, branched 283-219-6 84583-68-6 Sub-chronic toxicity (90-day): oral 12/04/2017 29/05/2017 Details
2-ethylaminoethanol 203-797-5 110-73-6 Sub-chronic toxicity (90-day): oral 18/02/2014 04/04/2014 Details
2-methylbut-3-yn-2-ol 204-070-5 115-19-5 Sub-chronic toxicity (90-day): oral 20/04/2015 08/06/2015 Details
2-piperazin-1-ylethylamine 205-411-0 140-31-8 Sub-chronic toxicity (90-day): oral 21/10/2011 05/12/2011 Details
2-Propenoic acid, 1,1'-[(1-methyl-1,2-ethanediyl)bis[oxy(methyl-2,1-ethanediyl)]] ester, reaction products with diethylamine 601-101-8 111497-86-0 Sub-chronic toxicity (90-day): oral 18/02/2021 05/04/2021 Details
2-Propyn-1-ol, compd. with methyloxirane 609-530-2 38172-91-7 Sub-chronic toxicity (90-day): oral 16/10/2014 01/12/2014 Details
3,5,5-trimethylhexyl 3,5,5-trimethylhexanoate 261-665-2 59219-71-5 Sub-chronic toxicity (90-day): oral 24/02/2020 09/04/2020 Details
3-(Diisobutoxy-thiophosphorylsulfanyl)-2-methyl-propionic acid 434-070-2 - Sub-chronic toxicity (90-day): oral 18/02/2013 04/04/2013 Details
3-C12-14-(even numbered)-alkylamido-N,N-dimethylpropan-1-amino oxide 931-324-9 - Sub-chronic toxicity (90-day): oral 02/09/2011 17/10/2011 Details
3-methoxy-3-methylbutan-1-ol 260-252-4 56539-66-3 Sub-chronic toxicity (90-day): oral 18/09/2014 03/11/2014 Details
4,4'-[(isopropylidene)bis(p-phenyleneoxy)]diphthalic dianhydride 253-781-7 38103-06-9 Sub-chronic toxicity (90-day): oral 27/01/2020 12/03/2020 Details
4-(1-methyl-1-phenylethyl)-N-[4-(1-methyl-1-phenylethyl)phenyl]aniline 233-215-5 10081-67-1 Sub-chronic toxicity (90-day): oral 18/02/2014 04/04/2014 Details
4-methylmorpholine 203-640-0 109-02-4 Sub-chronic toxicity (90-day): oral 25/11/2021 10/01/2022 Details
4-morpholinecarbaldehyde 224-518-3 4394-85-8 Sub-chronic toxicity (90-day): oral 04/04/2014 19/05/2014 Details
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one 403-830-5 89331-94-2 Sub-chronic toxicity (90-day): oral 02/09/2013 18/10/2013 Details
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one 403-830-5 89331-94-2 Sub-chronic toxicity (90-day): oral 26/03/2018 11/05/2018 Details
7-amino-3,8-bis-[4-(2-sulfoxyethylsulfonyl)-2-sulfophenylazo]-4-hydroxynaphthalene-2-sulfonic acid, Na/K salt; 7-amino-3-[4-(2-sulfoxyethylsulfonyl)phenylazo]-4-hydroxy-8-[4-(2-sulfoxyethylsulfonyl)-2-sulfophenylazo]naphthalene-2-sulfonic acid, Na/K salt; 7-amino-8-[4-(2-sulfoxyethylsulfonyl)-phenylazo]-4-hydroxy-3-[4-(2-sulfoxyethylsulfonyl)-2-sulfophenylazo]naphthalene-2-sulfonic acid, Na/K salt; reaction mass of: 7-amino-3,8-bis-[4-(2-sulfoxyethylsulfonyl)phenylazo]-4-hydroxynaphthalene-2-sulfonic acid, Na/K salt 429-070-4 - Sub-chronic toxicity (90-day): oral 22/04/2021 07/06/2021 Details
Acetalization products between glucose and C16-18(even numbered)- alcohol 927-870-2 - Sub-chronic toxicity (90-day): oral 15/09/2011 31/10/2011 Details
Acetalization products between glucose and C20-22(even numbered)- alcohol 923-835-0 - Sub-chronic toxicity (90-day): oral 15/09/2011 31/10/2011 Details
ALCOHOLS, C11-14-ISO-, C13-RICH 271-235-6 68526-86-3 Sub-chronic toxicity (90-day): oral 31/05/2016 15/07/2016 Details
ALCOHOLS, C7-9-ISO-, C8-RICH 271-231-4 68526-83-0 Sub-chronic toxicity (90-day): oral 31/05/2016 15/07/2016 Details
Alkenes, C13-14 931-071-4 - Sub-chronic toxicity (90-day): oral 25/06/2012 09/08/2012 Details
Alkenes, C6-8, even and odd, linear and branched - - Sub-chronic toxicity (90-day): oral 25/06/2012 09/08/2012 Details
Amides, C16-C18 (even) , N,N'-ethylenebis 931-299-4 - Sub-chronic toxicity (90-day): oral 16/08/2011 30/09/2011 Details
Amines, C11-14-branched alkyl, monohexyl and dihexyl phosphates 279-632-6 80939-62-4 Sub-chronic toxicity (90-day): oral 23/11/2020 07/01/2021 Details
Benzenamine, reaction products with aniline hydrochloride and nitrobenzene, hydrochlorides 309-913-1 101357-16-8 Sub-chronic toxicity (90-day): oral 21/09/2020 05/11/2020 Details
Benzoic acid, 2-hydroxy-, mono-C>13-alkyl derivs., calcium salts (2:1) 281-018-8 83846-43-9 Sub-chronic toxicity (90-day): oral 18/06/2018 02/08/2018 Details
Bis(2,4,4-trimethylpentyl)phosphinic acid 280-445-7 83411-71-6 Sub-chronic toxicity (90-day): oral 18/03/2021 03/05/2021 Details
Bis(triethoxysilylpropyl)amine 236-818-1 13497-18-2 Sub-chronic toxicity (90-day): oral 22/09/2022 07/11/2022 Details
bismuth hydroxide nitrate oxide 215-136-8 1304-85-4 Sub-chronic toxicity (90-day): oral 18/09/2014 03/11/2014 Details
Butyl (dialkyloxy(dibutoxyphosphoryloxy))titanium(trialkyloxy)titanium phosphate 401-100-0 - Sub-chronic toxicity (90-day): oral 27/05/2019 11/07/2019 Details
Butyl glycollate 230-991-7 7397-62-8 Sub-chronic toxicity (90-day): oral 15/04/2011 30/05/2011 Details
calcium bis(di C8-C10, branched, C9 rich, alkylnaphthalenesulphonate) 939-717-7 - Sub-chronic toxicity (90-day): oral 02/06/2014 17/07/2014 Details
Camphene 201-234-8 79-92-5 Sub-chronic toxicity (90-day): oral 24/02/2020 09/04/2020 Details
Cyclohexylidenebis[tert-butyl] peroxide 221-111-2 3006-86-8 Sub-chronic toxicity (90-day): oral 21/03/2014 05/05/2014 Details
Dimethoxymethylsilane 240-914-9 16881-77-9 Sub-chronic toxicity (90-day): oral 25/05/2020 09/07/2020 Details
Disilver oxide 243-957-1 20667-12-3 Sub-chronic toxicity (90-day): oral 15/04/2011 30/05/2011 Details
Dodecene, hydroformylation products, low-boiling 271-240-3 68526-92-1 Sub-chronic toxicity (90-day): oral 29/04/2014 13/06/2014 Details
Dodecyl methacrylate 205-570-6 142-90-5 Sub-chronic toxicity (90-day): oral 03/04/2023 22/05/2023 Details
Ethylene dimethacrylate 202-617-2 97-90-5 Sub-chronic toxicity (90-day): oral 03/10/2023 17/11/2023 Details
Glycerol, propoxylated, esters with acrylic acid 500-114-5 52408-84-1 Sub-chronic toxicity (90-day): oral 22/11/2017 08/01/2018 Details
Guanidinium phosphate (1:1) 226-551-9 5423-22-3 Sub-chronic toxicity (90-day): oral 16/05/2014 30/06/2014 Details
hexahydrophthalic acid diglycidylester 696-026-0 1395383-69-3 Sub-chronic toxicity (90-day): oral 16/10/2014 01/12/2014 Details
Hydroxyethylated 2-butyne-1,4-diol 608-711-3 32167-31-0 Sub-chronic toxicity (90-day): oral 17/06/2014 01/08/2014 Details
Imidazolium compounds, 2-C17-unsatd.-alkyl-1-(2-C18-unsatd. amidoethyl)-4,5-dihydro-N-methyl, Me sulfates 931-745-8 - Sub-chronic toxicity (90-day): oral 01/07/2011 15/08/2011 Details
Isononanoic acid, C16-18 (even numbered)-alkyl esters 601-141-6 111937-03-2 Sub-chronic toxicity (90-day): oral 18/09/2014 03/11/2014 Details
Isononyl isononanoate 609-993-0 42131-25-9 Sub-chronic toxicity (90-day): oral 18/09/2014 03/11/2014 Details
l-Glutamic acid, N-coco acyl derivs., disodium salts 269-085-1 68187-30-4 Sub-chronic toxicity (90-day): oral 22/09/2022 07/11/2022 Details
methyl-1h-benzotriazole 249-596-6 29385-43-1 Sub-chronic toxicity (90-day): oral 16/12/2020 01/02/2021 Details
N,N-bis(2-ethylhexyl)-5-methyl-1H-benzotriazole-1-methylamine, N,N-bis(2-ethylhexyl)-4-methyl-1H-benzotriazole-1-methylamine, 2H-Benzotriazole-2-methanamine, N,N-bis(2-ethylhexyl)-4-methyl-, 2H-Benzotriazole-2-methanamine, N,N-bis(2-ethylhexyl)-5-methyl-, 1H-Benzotriazole-1-methanamine, N,N-bis(2-ethylhexyl)-6-methyl-(Mixture) 939-700-4 - Sub-chronic toxicity (90-day): oral 21/10/2019 05/12/2019 Details
N-[(3-methyl-1H-pyrazol-1-yl)methyl]acetamide; N-[(5-methyl-1H-pyrazol-1-yl)methyl]acetamide 700-208-8 - Sub-chronic toxicity (90-day): oral 04/10/2018 19/11/2018 Details
O,O,O-triphenyl phosphorothioate 209-909-9 597-82-0 Sub-chronic toxicity (90-day): oral 16/12/2016 30/01/2017 Details
Octadecylamine, reaction products with 4,4'-methylenediphenyl diisocyanate 928-226-3 - Sub-chronic toxicity (90-day): oral 16/10/2014 01/12/2014 Details
Octylphosphonic acid 225-218-5 4724-48-5 Sub-chronic toxicity (90-day): oral 03/04/2023 22/05/2023 Details
Pentane-1,2-diol 226-285-3 5343-92-0 Sub-chronic toxicity (90-day): oral 16/06/2011 01/08/2011 Details
pentasodium 5-{[4-chloro-6-({4-[2-(sulfooxy)ethanesulfonyl]phenyl}amino)-1,3,5-triazin-2-yl]amino}-3-[2-(1,5-disulfonaphthalen-2-yl)diazen-1-yl]-4-hydroxynaphthalene-2,7-disulfonate 402-420-3 89157-03-9 Sub-chronic toxicity (90-day): oral 25/06/2019 09/08/2019 Details
Phosphonium, tetrakis(hydroxymethyl)-, chloride (1:1), reaction products with 1-tetradecanamine and urea 436-230-7 359406-89-6 Sub-chronic toxicity (90-day): oral 06/03/2012 20/04/2012 Details
Poly[oxy(methyl-1,2-ethanediyl)], α,α'-(2,2-dimethyl-1,3-propanediyl)bis[ω-hydroxy-] 610-848-9 52479-58-0 Sub-chronic toxicity (90-day): oral 18/09/2014 03/11/2014 Details
Polysulfides, bis[3-(triethoxysilyl)propyl] 915-673-4 - Sub-chronic toxicity (90-day): oral 21/10/2021 07/12/2021 Details
Polysulfides, di-tert-nonyl 270-336-2 68425-16-1 Sub-chronic toxicity (90-day): oral 06/09/2018 22/10/2018 Details
Reaction mass of 1-(C12-18-(even numbered))-alkyl-tetrahydropyrimidin-2(1H)-imine acetate salt and 1-(3-((C12-18-(even numbered))-alkyl-amino)propyl)guanidine acetate salt and 1-(C12-18-(even numbered))-alkyl-1-(3-guanidinopropyl)guanidine acetate salt 939-650-3 - Sub-chronic toxicity (90-day): oral 10/05/2022 27/06/2022 Details
Reaction mass of 2,2'-[(4-methylphenyl)imino]bisethanol and Ethanol 2-[[2-(2-hydroxyethoxy)ethyl](4-methylphenyl)amino]- 911-490-9 - Sub-chronic toxicity (90-day): oral 27/05/2019 11/07/2019 Details
Reaction mass of 2,7-Naphthalenedisulfonic acid, 5-amino-3-[[4-[2-[4-[(7-amino-1-hydroxy-3-sulfo-2-naphthalenyl)azo]-2-sulfophenyl]ethenyl]-3-sulfophenyl]azo]-4-hydroxy-, compd. with 2,2',2''-nitrilotris[ethanol] (1:5) and 3,3'-[ethylenebis[(3-sulpho-p-phenylene)azo]]bis[5-amino-4-hydroxynaphthalene-2,7-disulphonic] acid, compound with 2,2',2''-nitrilotriethanol (1:6) and 3,3'-[vinylenebis[(3-sulpho-p-phenylene)azo]]bis[6-amino-4-hydroxynaphthalene-2-sulphonic] acid, compound with 2,2',2''-nitrilotriethanol (1:4) 916-899-6 - Sub-chronic toxicity (90-day): oral 10/08/2018 24/09/2018 Details
Reaction mass of 3-isopropyl-6-methylenecyclohexene and (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohexene and (4S)-1-methyl-4-(prop-1-en-2-yl)cyclohexene 939-009-8 - Sub-chronic toxicity (90-day): oral 21/12/2021 04/02/2022 Details
Reaction mass of Amines, coco alkyl and β-Alanine, N-(2-carboxyethyl)-, N-coco alkyl derivs. and β-Alanine, N-coco alkyl derivs. 915-790-0 - Sub-chronic toxicity (90-day): oral 12/12/2014 26/01/2015 Details
Reaction mass of Benzeneacetic acid, alpha-oxo-, 1,1'-(oxydi-2,1-ethanediyl) ester and Benzeneacetic acid, alpha-oxo-, 2-(2-hydroxyethoxy)ethyl ester 442-300-8 - Sub-chronic toxicity (90-day): oral 04/10/2013 18/11/2013 Details
Reaction mass of butane-2,2-diyl dihydroperoxide and di-sec-butylhexaoxidane 700-954-4 1338-23-4 Sub-chronic toxicity (90-day): oral 19/12/2013 03/02/2014 Details
Reaction mass of sodium 1-methoxy-1-oxohexadecane-2-sulphonate and sodium methyl 2-sulphooctadecanoate 911-616-2 - Sub-chronic toxicity (90-day): oral 25/05/2020 09/07/2020 Details
Reaction mass of trisodium [μ-[4-[[3,3'-dihydroxy-4'-[(2-hydroxy-6-sulpho-1-naphthyl)azo][1,1'-biphenyl]-4-yl]azo]-3-hydroxynaphthalene-2,7-disulphonato(7-)]]dicuprate(3-) and triammonium [μ-[4-[[3,3'-dihydroxy-4'-[(2-hydroxy-6-sulpho-1-naphthyl)azo][1,1'-biphenyl]-4-yl]azo]-3-hydroxynaphthalene-2,7-disulphonato(7-)]]dicuprate(3-) 945-577-8 - Sub-chronic toxicity (90-day): oral 01/07/2021 16/08/2021 Details
Reaction products of tryglycerides, C8-C18 (even numbered) and C18-unsaturated, glycerine and ethylene oxide 939-459-5 - Sub-chronic toxicity (90-day): oral 30/11/2015 14/01/2016 Details
Silver 231-131-3 7440-22-4 Sub-chronic toxicity (90-day): oral 29/04/2011 14/06/2011 Details
Silver nitrate 231-853-9 7761-88-8 Sub-chronic toxicity (90-day): oral 16/06/2011 01/08/2011 Details
Sodium dihydrogenorthophosphate 231-449-2 7558-80-7 Sub-chronic toxicity (90-day): oral 24/07/2019 09/09/2019 Details
Sodium p-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]benzenesulphonate 223-989-2 4156-21-2 Sub-chronic toxicity (90-day): oral 29/04/2014 13/06/2014 Details
Tar, brown-coal, low-temp. 309-886-6 101316-84-1 Sub-chronic toxicity (90-day): oral 29/07/2011 12/09/2011 Details
tellurium dioxide 231-193-1 7446-07-3 Sub-chronic toxicity (90-day): oral 16/03/2015 30/04/2015 Details
Tetrakis(hydroxymethyl)phosphonium chloride, oligomeric reaction products with urea 500-057-6 27104-30-9 Sub-chronic toxicity (90-day): oral 02/09/2011 17/10/2011 Details
Tetramethylammonium chloride 200-880-8 75-57-0 Sub-chronic toxicity (90-day): oral 29/04/2014 13/06/2014 Details
triethoxy(methyl)silane 217-983-9 2031-67-6 Sub-chronic toxicity (90-day): oral 25/05/2020 09/07/2020 Details
Triisotridecyl phosphite 278-758-9 77745-66-5 Sub-chronic toxicity (90-day): oral 25/06/2019 09/08/2019 Details
Vinyl ethylene carbonate 700-261-7 4427-96-7 Sub-chronic toxicity (90-day): oral 30/06/2023 14/08/2023 Details
Vinyl laurate 218-414-7 2146-71-6 Sub-chronic toxicity (90-day): oral 16/05/2011 30/06/2011 Details
Pentasodium triphosphate 231-838-7 7758-29-4 Sub-chronic toxicity (90-day) via the inhalatory route (rat) 08/04/2010 24/05/2010 Details
bismuth oxide salicylate 238-953-1 14882-18-9 Sub-chronic toxicity (90 day): oral || Note: testing proposed with bismuth hydroxide nitrate oxide (EC 215-136-8) 18/09/2014 03/11/2014 Details
Fatty acids, tall-oil, reaction products with 2-[(2-aminoethyl)amino]ethanol 272-902-4 68919-76-6 Sub-chronic toxicity (90 day): oral 16/05/2014 30/06/2014 Details
Vinyl neononanoate 259-160-7 54423-67-5 Sub-chronic toxicity (90 day): oral 16/05/2012 02/07/2012 Details
Edetic acid 200-449-4 60-00-4 Sub-chronic toxicity (90 day): inhalation || Note: testing proposed with_Na2H2EDTA (identifier not available) 16/06/2011 01/08/2011 Details
Bis(2-chloroethyl) 3,3'-[(2,5-dimethyl-p-phenylene)bis[iminocarbonyl(2-hydroxy-1,3-naphthylene)azo]]di-p-toluate 269-507-4 68259-05-2 Sub-chronic toxicity (90 day): inhalation || Note: Testing proposal is based on concern identified by the registrant 24/07/2019 09/09/2019 Details
2-(2-Ethoxyethoxy)-2-methylpropanee 257-196-8 51422-54-9 Sub-chronic toxicity (90 day): inhalation Reproductive toxicity (pre-natal developmental toxicity) 03/02/2016 21/03/2016 Details
1,3-Benzenedimethanamine, N-(2-phenylethyl) derivs. 445-790-1 - Sub-chronic toxicity (90 day): inhalation 04/04/2014 19/05/2014 Details
3,3,4,4,5,5,6,6,6-nonafluorohexene 243-053-7 19430-93-4 Sub-chronic toxicity (90 day): inhalation 14/08/2014 28/09/2014 Details
3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate, oligomers, reaction products with 2-butanone oxime 500-287-7 103170-26-9 Sub-chronic toxicity (90 day): inhalation 12/12/2014 26/01/2015 Details
3-methylbutanone 209-264-3 563-80-4 Sub-chronic toxicity (90 day): inhalation 14/08/2014 28/09/2014 Details
Activated Carbon - High Density Skeleton 931-328-0 - Sub-chronic toxicity (90 day): inhalation 16/06/2011 01/08/2011 Details
Amorphous glass product formed from the melting and fiberisation of dipotassium oxide, oxo(oxoalumanyloxy)alumane and dioxosilane 931-219-8 - Sub-chronic toxicity (90 day): inhalation 24/05/2013 08/07/2013 Details
Calcium carbonate 207-439-9 471-34-1 Sub-chronic toxicity (90 day): inhalation 15/07/2011 29/08/2011 Details
Calcium dihydroxide precipitated with carbon dioxide during sugar juice purification 932-124-4 - Sub-chronic toxicity (90 day): inhalation 01/07/2011 15/08/2011 Details
Diammonium dihydrogen ethylenediaminetetraacetate 244-063-4 20824-56-0 Sub-chronic toxicity (90 day): inhalation 29/07/2011 12/09/2011 Details
dimethoxydimethylsilane 214-189-4 1112-39-6 Sub-chronic toxicity (90 day): inhalation 16/10/2014 01/12/2014 Details
Disodium dihydrogen 2,2',2'',2'''-(ethane-1,2-diyldinitrilo)tetraacetate 205-358-3 139-33-3 Sub-chronic toxicity (90 day): inhalation 16/06/2011 01/08/2011 Details
Dodecamethylcyclohexasiloxane 208-762-8 540-97-6 Sub-chronic toxicity (90 day): inhalation 31/05/2011 15/07/2011 Details
Halophosphate - - Sub-chronic toxicity (90 day): inhalation 15/07/2014 29/08/2014 Details
Hexamethylene diisocyanate, oligomerisation product, blocked with 3,5-dimethyl-1H-pyrazole 605-318-9 163206-31-3 Sub-chronic toxicity (90 day): inhalation 12/12/2014 26/01/2015 Details
Kieselguhr, soda ash flux-calcined 272-489-0 68855-54-9 Sub-chronic toxicity (90 day): inhalation 01/07/2011 15/08/2011 Details
Slags, steelmaking, elec. furnace (stainless/high alloy steel production) 932-476-9 - Sub-chronic toxicity (90 day): inhalation 06/03/2012 20/04/2012 Details
tert-dodecanethiol 246-619-1 25103-58-6 Sub-chronic toxicity (90 day): inhalation 14/11/2013 30/12/2013 Details
Tetraammonium ethylenediaminetetraacetate 245-022-3 22473-78-5 Sub-chronic toxicity (90 day): inhalation 16/06/2011 01/08/2011 Details
tetrapotassium pyrophosphate 230-785-7 7320-34-5 Sub-chronic toxicity (90 day): inhalation 01/07/2011 15/08/2011 Details
Tetrasodium ethylenediaminetetraacetate 200-573-9 64-02-8 Sub-chronic toxicity (90 day): inhalation 16/06/2011 01/08/2011 Details
tin monoxide 244-499-5 21651-19-4 Sub-chronic toxicity (90 day): inhalation 23/01/2015 09/03/2015 Details
Triammonium hydrogen ethylenediaminetetraacetate 240-073-8 15934-01-7 Sub-chronic toxicity (90 day): inhalation 16/06/2011 01/08/2011 Details
Trifluoro(trifluoromethoxy)ethylene 214-703-7 1187-93-5 Sub-chronic toxicity (90 day): inhalation 29/04/2014 13/06/2014 Details
Hydrazine 206-114-9 302-01-2 Sub-chronic toxicity (28 day): inhalation 15/07/2011 29/08/2011 Details
Ethoxypropyl-hydroxy-hexanamide - - Reproductive/developmental toxicity 04/12/2009 18/01/2010 Details
Polysulfides, bis[3-(triethoxysilyl)propyl] 915-673-4 - Reproductive/developmental toxicity 22/12/2010 07/02/2011 Details
Icosane 204-018-1 112-95-8 Reproductive toxicity (two-generation reproductive toxicity)// Note: Testing proposed with Hydrocarbon, C9-C12, normal, isoalkane, cyclics, 2-25% aromatics; Hydrocarbon, C16-C20, normal, isoalkane cyclics, 2-30% aromatics 02/07/2013 16/08/2013 Details
Benzenamine, N-phenyl-, reaction products with 2,4,4-trimethylpentene 270-128-1 68411-46-1
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity study (90-day): oral
05/04/2011
05/04/2011
20/05/2011
20/05/2011
 Details
2-[2-(2-ethoxyethoxy)ethoxy]ethyl methacrylate 254-588-0 39670-09-2
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2014
16/05/2014
30/06/2014
30/06/2014
 Details
Alcohols, C18-22, distn. residues 641-136-6 -
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2011
15/07/2011
29/08/2011
29/08/2011
 Details
Bis(nonylphenyl)amine / Reaction products of Benzeneamine, N-phenyl- with nonene (branched) - -
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
28/02/2011
28/02/2011
14/04/2011
14/04/2011
 Details
Isooctyl acrylate 249-707-8 29590-42-9
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/03/2011
15/03/2011
29/04/2011
29/04/2011
 Details
Tetrapropylenebenzene 246-772-4 25265-78-5
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/09/2011
15/09/2011
31/10/2011
31/10/2011
 Details
Triethoxy(2,4,4-trimethylpentyl)silane 252-558-1 35435-21-3
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
29/04/2011
29/04/2011
14/06/2011
14/06/2011
 Details
3-trimethoxysilylpropyl methacrylate 219-785-8 2530-85-0
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): inhalation
15/04/2011
15/04/2011
30/05/2011
30/05/2011
 Details
N-ethyl-2-pyrrolidone (NEP) 220-250-6 2687-91-4
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day) via the inhalatory route
26/01/2011
26/01/2011
14/03/2011
14/03/2011
 Details
2,4,6,8,10-pentamethylcyclopentasiloxane 228-204-7 6166-86-5
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with 2,4,6,8-Tetramethylcyclotetrasiloxane (EC 219-137-4, CAS 2370-88-9)
Sub-chronic toxicity (90 day): inhalation || Note: testing proposed with 2,4,6,8-Tetramethylcyclotetrasiloxane (EC 219-137-4, CAS 2370-88-9)
04/10/2013
04/10/2013
18/11/2013
18/11/2013
 Details
Fatty acids, tall-oil, reaction products with formaldehyde and (Z)-N-9-octadecenyl-1,3-propanediamine 272-789-1 68911-83-1 Reproductive toxicity (two-generation reproductive toxicity) || Note: Testing proposal is based on concern identified by the registrant. 15/07/2014 29/08/2014 Details
Hydrocarbons, C14-C17, isoalkanes, cyclics, <2% aromatics 939-601-6 - Reproductive toxicity (two-generation reproductive toxicity) // Note: testing proposed with Icosane (C20 normal alkanes); Hydrocarbons, C14-C19, isoalkane, cyclics, < 2%; Hydrocarbon, C16-C20, normal, isoalkane, cyclics, 2-30% aromatics 02/06/2014 17/07/2014 Details
6-phenyl-1,3,5-triazine-2,4-diamine 202-095-6 91-76-9 Reproductive toxicity (two-generation reproductive toxicity) Reproductive toxicity (pre-natal developmental toxicity) 12/06/2013 29/07/2013 Details
N,N-bis[3-(dimethylamino)propyl]-N',N'-dimethylpropane-1,3-diamine 251-459-0 33329-35-0 Reproductive toxicity (two-generation reproductive toxicity) Note: testing proposed with structurally-related compound 29/04/2014 13/06/2014 Details
(1-methylethylidene)di-4,1-phenylene tetraphenyl diphosphate,Bisphenol A Diphosphate,Bisphenol A Polyphosphate 425-220-8 5945-33-5 Reproductive toxicity (two-generation reproductive toxicity) 05/04/2011 20/05/2011 Details
1,2,3,4-tetrahydronaphthalene 204-340-2 119-64-2 Reproductive toxicity (two-generation reproductive toxicity) 16/06/2011 01/08/2011 Details
1,3,5-Tris(oxiran-2-ylmethyl)-1,3,5-triazinane-2,4,6-trione (TGIC) 219-514-3 2451-62-9 Reproductive toxicity (two-generation reproductive toxicity) 19/11/2010 03/01/2011 Details
1,3-dimethylimidazolidin-2-one 201-304-8 80-73-9 Reproductive toxicity (two-generation reproductive toxicity) 15/04/2014 30/05/2014 Details
2,2'-ethylenedioxydiethyl bis(2-ethylhexanoate) 202-319-2 94-28-0 Reproductive toxicity (two-generation reproductive toxicity) 18/09/2014 03/11/2014 Details
2,5-Furandione, dihydro-, mono-C15-20-alkenyl derivs. 272-221-2 68784-12-3 Reproductive toxicity (two-generation reproductive toxicity) 02/02/2012 19/03/2012 Details
2,6-dimethyloct-7-en-2-ol 242-362-4 18479-58-8 Reproductive toxicity (two-generation reproductive toxicity) 14/02/2011 31/03/2011 Details
2-chloropropane 200-858-8 75-29-6 Reproductive toxicity (two-generation reproductive toxicity) 16/05/2011 30/06/2011 Details
2-Hexyldecan-1-ol 219-370-1 2425-77-6 Reproductive toxicity (two-generation reproductive toxicity) 05/04/2011 20/05/2011 Details
2-methylpentane-2,4-diol 203-489-0 107-41-5 Reproductive toxicity (two-generation reproductive toxicity) 16/06/2011 01/08/2011 Details
2-Octyldodecan-1-ol 226-242-9 5333-42-6 Reproductive toxicity (two-generation reproductive toxicity) 05/04/2011 20/05/2011 Details
2-phenylethanol 200-456-2 60-12-8 Reproductive toxicity (two-generation reproductive toxicity) 15/04/2014 30/05/2014 Details
3,6-bis(4-tert-butylphenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione 416-250-2 - Reproductive toxicity (two-generation reproductive toxicity) 25/09/2012 12/11/2012 Details
3,6-bis-biphenyl-4-yl-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione 413-920-6 - Reproductive toxicity (two-generation reproductive toxicity) 25/09/2012 12/11/2012 Details
6,6`-di-tert-butyl-2,2`-methylenedi-p-cresol 204-327-1 119-47-1 Reproductive toxicity (two-generation reproductive toxicity) 16/05/2011 30/06/2011 Details
Alkanes, C10-13, chloro (Short Chain Chlorinated Paraffins) 287-476-5 85535-84-8 Reproductive toxicity (two-generation reproductive toxicity) 29/07/2011 12/09/2011 Details
Alkanes, C10-13-iso- 271-366-9 68551-17-7 Reproductive toxicity (two-generation reproductive toxicity) 25/06/2012 09/08/2012 Details
Alkanes, C12-26-branched and linear 292-454-3 90622-53-0 Reproductive toxicity (two-generation reproductive toxicity) 15/09/2011 31/10/2011 Details
Alkenes, C11-12, hydroformylation products, low boiling 932-235-8 - Reproductive toxicity (two-generation reproductive toxicity) 16/06/2011 01/08/2011 Details
Alkenes, C13-14, hydroformylation products, low boiling - - Reproductive toxicity (two-generation reproductive toxicity) 29/07/2011 12/09/2011 Details
Amines, polyethylenepoly-, triethylenetetramine fraction,Triethylenetetramine linear, cyclic and branched 292-588-2 90640-66-7 Reproductive toxicity (two-generation reproductive toxicity) 05/04/2011 20/05/2011 Details
Barium diboron tetraoxide 237-222-4 13701-59-2 Reproductive toxicity (two-generation reproductive toxicity) 16/05/2014 30/06/2014 Details
Chloroacetic acid 201-178-4 79-11-8 Reproductive toxicity (two-generation reproductive toxicity) 16/06/2011 01/08/2011 Details
Condensates (petroleum), vacuum tower 265-049-4 64741-49-7 Reproductive toxicity (two-generation reproductive toxicity) 15/09/2011 31/10/2011 Details
decahydronaphthalene 202-046-9 91-17-8 Reproductive toxicity (two-generation reproductive toxicity) 15/07/2011 29/08/2011 Details
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