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Previous Testing Proposals

Previous Testing Proposals

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

 
Sodium N-(2-carboxyethyl)-N-(2-ethylhexyl)-β-alaninate 305-318-6 94441-92-6 Reproductive toxicity (pre-natal developmental toxicity) 02/06/2014 17/07/2014
2,2-dimethylpropane-1,3-diyl cyclohex-4-ene-1,2-dicarboxylate 255-180-5 41026-17-9
Sub-chronic toxicity (90-day): oral
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
16/05/2014
16/05/2014
16/05/2014
16/05/2014
30/06/2014
30/06/2014
30/06/2014
30/06/2014
Reaction mass of N-[2-(2-oxoimidazolidin-1-yl)ethyl]methacrylamide and methacrylic acid 934-058-1 -
Genetic toxicity in vivo
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2014
16/05/2014
16/05/2014
16/05/2014
30/06/2014
30/06/2014
30/06/2014
30/06/2014
1,6-hexanediyl-bis(2-(2-(1-ethylpentyl)-3-oxazolidinyl)ethyl)carbamate 925-259-5 140921-24-0
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2014
16/05/2014
16/05/2014
30/06/2014
30/06/2014
30/06/2014
2,3-epoxypropyl o-tolyl ether 218-645-3 2210-79-9
Reproductive toxicity (two-generation reproductive toxicity)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2014
16/05/2014
16/05/2014
30/06/2014
30/06/2014
30/06/2014
2-[methyl[(nonafluorobutyl)sulphonyl]amino]ethyl acrylate 266-733-5 67584-55-8
Reproductive toxicity (two-generation reproductive toxicity)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2014
16/05/2014
16/05/2014
30/06/2014
30/06/2014
30/06/2014
1,6-Bis-[(2,2-dimethyl-3-lauroyloxy-propylidene)-amino]hexane 479-930-8 613222-52-9
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
16/05/2014
16/05/2014
30/06/2014
30/06/2014
2-[2-(2-ethoxyethoxy)ethoxy]ethyl methacrylate 254-588-0 39670-09-2
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2014
16/05/2014
30/06/2014
30/06/2014
2-Oxepanone, polymer with 1,4-butanediol 608-670-1 31831-53-5
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
16/05/2014
16/05/2014
30/06/2014
30/06/2014
Aminoiminomethanesulphinic acid 217-157-8 1758-73-2
Reproductive toxicity (two-generation reproductive toxicity)
Reproductive toxicity (pre-natal developmental toxicity)
16/05/2014
16/05/2014
30/06/2014
30/06/2014
Bis[2-[2-(1-methylethyl)-3-oxazolidinyl]ethyl] hexan-1,2-diylbiscarbamate 261-879-6 59719-67-4
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
16/05/2014
16/05/2014
30/06/2014
30/06/2014
Ethyl phenyl(2,4,6-trimethylbenzoyl)phosphinate 282-810-6 84434-11-7
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
16/05/2014
16/05/2014
30/06/2014
30/06/2014
O-isopropyl ethylthiocarbamate 205-517-7 141-98-0
Sub-chronic toxicity (90 day): oral
Reproductive toxicity (pre-natal developmental toxicity)
16/05/2014
16/05/2014
30/06/2014
30/06/2014
Octadecanoic acid, 12-hydroxy-, reaction products with ethylenediamine 309-629-8 100545-48-0
Sub-chronic toxicity (90 day): inhalation
Reproductive toxicity (pre-natal developmental toxicity)
16/05/2014
16/05/2014
30/06/2014
30/06/2014
1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-nortall-oil alkyl derivs. 263-171-2 61791-39-7 Bioaccumulation aquatic / sediment 16/05/2014 30/06/2014
2-(2-naphthyloxy)ethanol 202-228-8 93-20-9 Genetic toxicity in vivo 16/05/2014 30/06/2014
Amines, C16-22-alkyl 268-215-4 68037-92-3 Reproductive toxicity (pre-natal developmental toxicity) 16/05/2014 30/06/2014
Barium diboron tetraoxide 237-222-4 13701-59-2 Reproductive toxicity (two-generation reproductive toxicity) 16/05/2014 30/06/2014
Bis(2-ethylhexyl) tetrabromophthalate 247-426-5 26040-51-7 Reproductive toxicity (pre-natal developmental toxicity) 16/05/2014 30/06/2014
Fatty acids, C16-C18 and C18-unsatd., ME esters, epoxidized 605-143-8 158318-67-3 Reproductive toxicity (pre-natal developmental toxicity) 16/05/2014 30/06/2014
Fatty acids, tall-oil, reaction products with 2-[(2-aminoethyl)amino]ethanol 272-902-4 68919-76-6 Sub-chronic toxicity (90 day): oral 16/05/2014 30/06/2014
Formaldehyde, reaction products with ethylenediamine 281-928-5 84066-92-2 Genetic toxicity in vivo 16/05/2014 30/06/2014
Guanidinium phosphate (1:1) 226-551-9 5423-22-3 Sub-chronic toxicity (90-day): oral 16/05/2014 30/06/2014
Octylphosphonic acid 225-218-5 4724-48-5 Reproductive toxicity (pre-natal developmental toxicity) 16/05/2014 30/06/2014
Propylidynetrimethanol 201-074-9 77-99-6 Reproductive toxicity (pre-natal developmental toxicity) // Note: testing proposed on rabbits 16/05/2014 30/06/2014
Sodium hydrogen N-(1-oxododecyl)-L-glutamate 249-958-3 29923-31-7 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with CAS 68187-30-4 16/05/2014 30/06/2014
2-Propenoic acid, 2-methyl-, 2-hydroxyethyl ester, phosphate 258-053-2 52628-03-2
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
29/04/2014
29/04/2014
13/06/2014
13/06/2014
Bis(2,4,4-trimethylpentyl)phosphinic acid 280-445-7 83411-71-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
29/04/2014
29/04/2014
13/06/2014
13/06/2014
Sodium 3-(allyloxy)-2-hydroxypropanesulphonate 258-004-5 52556-42-0
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
29/04/2014
29/04/2014
13/06/2014
13/06/2014
Sodium O,O-diisobutyl dithiophosphate 258-508-5 53378-51-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
29/04/2014
29/04/2014
13/06/2014
13/06/2014
2-[(2-methyl-1-oxoallyl)oxy]ethyl acetoacetate 244-311-1 21282-97-3 Genetic toxicity in vivo 29/04/2014 13/06/2014
Bis(1,2,2,6,6-pentamethyl-4-piperidyl) [[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methyl]butylmalonate 264-513-3 63843-89-0 Genetic toxicity in vivo 29/04/2014 13/06/2014
bis(piperidinothiocarbonyl) hexasulphide 213-537-2 971-15-3 Reproductive toxicity (pre-natal developmental toxicity) 29/04/2014 13/06/2014
Dodecene, hydroformylation products, low-boiling 271-240-3 68526-92-1 Sub-chronic toxicity (90-day): oral 29/04/2014 13/06/2014
N,N-bis[3-(dimethylamino)propyl]-N',N'-dimethylpropane-1,3-diamine 251-459-0 33329-35-0 Reproductive toxicity (two-generation reproductive toxicity) Note: testing proposed with structurally-related compound 29/04/2014 13/06/2014
Sodium 2-[(2-aminoethyl)amino]ethanesulphonate 252-173-9 34730-59-1 Reproductive toxicity (pre-natal developmental toxicity) 29/04/2014 13/06/2014
Sodium hydrogen-5-sulphoisophthalate 228-845-2 6362-79-4 Genetic toxicity in vivo 29/04/2014 13/06/2014
Sodium p-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]benzenesulphonate 223-989-2 4156-21-2 Sub-chronic toxicity (90-day): oral 29/04/2014 13/06/2014
Tetramethylammonium chloride 200-880-8 75-57-0 Sub-chronic toxicity (90-day): oral 29/04/2014 13/06/2014
Trifluoro(trifluoromethoxy)ethylene 214-703-7 1187-93-5 Sub-chronic toxicity (90 day): inhalation 29/04/2014 13/06/2014
Yttrium zirconium oxide 264-885-7 64417-98-7 Reproductive toxicity (pre-natal developmental toxicity) 29/04/2014 13/06/2014
Strontium hydroxide 242-367-1 18480-07-4
Long-term toxicity to fish Note: testing proposed with strontium dinitrate (EC: 233-131-9, CAS: 10042-76-9)
Reproductive toxicity (two-generation reproductive toxicity) Note: testing proposed with strontium dinitrate (EC: 233-131-9, CAS: 10042-76-9)
Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with strontium dinitrate (EC: 233-131-9, CAS: 10042-76-9)
15/04/2014
15/04/2014
15/04/2014
30/05/2014
30/05/2014
30/05/2014
Trimethyl borate 204-468-9 121-43-7
Sub-chronic toxicity (90-day): oral || Note: testing proposed with boric acid.
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with boric acid.
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with boric acid.
15/04/2014
15/04/2014
15/04/2014
30/05/2014
30/05/2014
30/05/2014
1,3-dihydro-4(or 5)-methyl-2H-benzimidazole-2-thione 258-904-8 53988-10-6
Reproductive toxicity (two-generation reproductive toxicity) Note: testing proposed with 1,3-dihydro-4(or 5)-methyl-2H-benzimidazole-2-thione, zinc salt (CAS: 61617-00-3)
Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with 1,3-dihydro-4(or 5)-methyl-2H-benzimidazole-2-thione, zinc salt (CAS: 61617-00-3)
15/04/2014
15/04/2014
30/05/2014
30/05/2014
1,3-dihydro-4(or 5)-methyl-2H-benzimidazole-2-thione, zinc salt 262-872-0 61617-00-3
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/04/2014
15/04/2014
30/05/2014
30/05/2014
1-methylimidazole 210-484-7 616-47-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/04/2014
15/04/2014
30/05/2014
30/05/2014
2-ethyl-4-methylimidazole 213-234-5 931-36-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/04/2014
15/04/2014
30/05/2014
30/05/2014
2-imidazolidone 204-436-4 120-93-4
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/04/2014
15/04/2014
30/05/2014
30/05/2014
2-phenoxyethyl acrylate 256-360-6 48145-04-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/04/2014
15/04/2014
30/05/2014
30/05/2014
4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with 3-aminomethyl-3,5,5-trimethylcyclohexylamine 500-101-4 38294-64-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/04/2014
15/04/2014
30/05/2014
30/05/2014



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