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Previous Testing Proposals

Previous Testing Proposals

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

 
Sodium hydroxymethanesulphinate 205-739-4 149-44-0
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/04/2011
15/04/2011
15/04/2011
30/05/2011
30/05/2011
30/05/2011
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C8-18(even numbered) acyl) derivs., hydroxides, inner salts 939-455-3 -
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): oral
18/09/2014
18/09/2014
18/09/2014
03/11/2014
03/11/2014
03/11/2014
2,4,6-tris(2,4,6-tribromophenoxy)-1,3,5-triazine 426-040-2 25713-60-4
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/06/2011
16/06/2011
16/06/2011
16/06/2011
01/08/2011
01/08/2011
01/08/2011
01/08/2011
2-Butenedioic acid (Z)-, ester with 1,2-propanediol, compd. with 2-(dibutylamino)ethanol 286-304-6 85204-10-0
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/06/2014
02/06/2014
02/06/2014
02/06/2014
17/07/2014
17/07/2014
17/07/2014
17/07/2014
Fatty acids, tall-oil, reaction products with triethanolamine 267-053-1 67784-78-5
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
29/07/2011
29/07/2011
29/07/2011
29/07/2011
12/09/2011
12/09/2011
12/09/2011
12/09/2011
Quaternary ammonium compounds, bis(hydrogenated tallow alkyl)dimethyl, chlorides, reaction products with polyethylenepolyamines and tall-oil fatty acids, humates hydrochlorides 272-745-1 68910-55-4
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90 day): inhalation
23/01/2015
23/01/2015
23/01/2015
23/01/2015
09/03/2015
09/03/2015
09/03/2015
09/03/2015
2,4,8,10-tetra(tert-butyl)-6-hydroxy-12H-dibenzo[d,g][1,3,2]dioxaphosphocin 6-oxide, sodium salt 286-344-4 85209-91-2
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
16/10/2014
16/10/2014
16/10/2014
01/12/2014
01/12/2014
01/12/2014
4-tert-butylpyrocatechol 202-653-9 98-29-3
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
29/04/2011
29/04/2011
29/04/2011
14/06/2011
14/06/2011
14/06/2011
Barium chloride 233-788-1 10361-37-2
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
29/04/2011
29/04/2011
29/04/2011
14/06/2011
14/06/2011
14/06/2011
Strontium nitrate 233-131-9 10042-76-9
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
31/05/2011
31/05/2011
31/05/2011
15/07/2011
15/07/2011
15/07/2011
Sulphamidic acid 226-218-8 5329-14-6
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
14/02/2011
14/02/2011
14/02/2011
31/03/2011
31/03/2011
31/03/2011
1,2-dihydroxybenzene,pyrocatechol 204-427-5 120-80-9
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
15/04/2011
15/04/2011
30/05/2011
30/05/2011
Ethanol, 2,2'-iminobis-, N-(C13-15-branched and linear alkyl) derivs. 308-208-6 97925-95-6
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
29/07/2011
29/07/2011
12/09/2011
12/09/2011
tert-butyl perbenzoate 210-382-2 614-45-9
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
16/06/2011
16/06/2011
01/08/2011
01/08/2011
Reaction mass of 2-(1,1-dimethylpropyl)anthraquinone and 2-(1,2-dimethylpropyl)anthraquinonedimethylpropyl)anthraquinone 915-623-1 -
Long-term toxicity to fish
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
27/09/2017
27/09/2017
27/09/2017
13/11/2017
13/11/2017
13/11/2017
Phosphoric acid, octadecyl ester 254-466-7 39471-52-8
Long-term toxicity to fish
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/04/2015
17/04/2015
17/04/2015
17/04/2015
04/06/2015
04/06/2015
04/06/2015
04/06/2015
N-octadecylstearamide 236-276-6 13276-08-9
Long-term toxicity to fish
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (pre-natal developmental toxicity)
17/04/2015
17/04/2015
17/04/2015
04/06/2015
04/06/2015
04/06/2015
Heptan-1-ol 203-897-9 111-70-6
Long-term toxicity to fish
Long-term toxicity to fish
Sub-chronic toxicity (90 day): Oral
04/09/2012
18/02/2014
04/09/2012
19/10/2012
04/04/2014
19/10/2012
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-C12-14 acyl derivs., hydroxides, inner salts 293-878-1 91648-19-0
Long-term toxicity to fish || Note: testing proposed with 1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C12-18(even numbered) acyl) derivs., hydroxides, inner salts (EC 939-457-4)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C8-18(even numbered) acyl) derivs., hydroxides, inner salts (EC 939-455-3)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C8-18(even numbered) acyl) derivs., hydroxides, inner salts (EC 939-455-3)
18/06/2018
18/06/2018
18/06/2018
02/08/2018
02/08/2018
02/08/2018
Triethoxy(2,4,4-trimethylpentyl)silane 252-558-1 35435-21-3
Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates.
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with triethoxyoctylsilane (CAS 2943-75-1)
28/02/2018
28/02/2018
16/04/2018
16/04/2018
Fats and Glyceridic oils, vegetable, winterized, reaction products with ammonia-ethanolamine reaction products 800-253-4 - Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates.

Link to registration dossier not given as the dossier not yet disseminated.
30/11/2015 14/01/2016
N,N'-ethane-1,2-diylbis(12-hydroxyoctadecan-1-amide) 204-613-6 123-26-2
Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with: “Octadecanoic acid, 12-hydroxy-, reaction products with ethylenediamine”, CAS 100545-48-0
Sub-chronic toxicity (90 day): oral
30/09/2015
30/09/2015
30/09/2015
16/11/2015
16/11/2015
16/11/2015
1,1,4,4-tetramethylbutane-1,4-diyl bis(2-ethylperoxyhexanoate) 235-935-5 13052-09-0 Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates 12/12/2014 26/01/2015
2-ethyl-2-[[(1-oxononyl)oxy]methyl]propane-1,3-diyl dinonan-1-oate 204-793-6 126-57-8 Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates 17/04/2015 04/06/2015
bis(piperidinothiocarbonyl) hexasulphide 213-537-2 971-15-3 Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates 16/02/2015 02/04/2015
tert-butyl α,α-dimethylbenzyl peroxide 222-389-8 3457-61-2 Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates 16/03/2015 30/04/2015
benzyl butyl cis-cyclohexane-1,2-dicarboxylate 701-279-8 1931129-39-3
Long-term toxicity to fish || Note: Link to the registration dossier not given as the dossier not yet disseminated. || Note: this substance was previously registered, identified and disseminated with EC No. 810-685-5
Reproductive toxicity (pre-natal developmental toxicity) || Note: Link to registration dossier not given as the dossier not yet disseminated. || Note: this substance was previously registered, identified and disseminated with EC No. 810-685-5
Sub-chronic toxicity (90-day): oral || Note: Link to registration dossier not given as the dossier not yet disseminated. || Note: this substance was previously registered, identified and disseminated with EC No. 810-685-5
10/12/2018
10/12/2018
10/12/2018
24/01/2019
24/01/2019
24/01/2019
Acetic acid, chloro-, sodium salt, reaction products with 4,5-dihydro-2-undecyl-1H-imidazole-1-ethanol and sodium hydroxide 271-794-6 68608-66-2 Long-term toxicity to fish Sub-chronic toxicity (90-day): oral || Note: testing proposed with Reaction products of 1H-Imidazole- 1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid (EC 931-291-0) Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid (EC 931-291-0 29/02/2016 14/04/2016
2,4,7,9-tetramethyl-4,7-decanediol 451-160-7 17913-76-7
Long-term toxicity to fish
"|| Note: testing proposed with 2,4,7,9-tetramethyldec-5-yne-4,7-diol (EC 204-809-1, CAS 126-86-3)
Reproductive toxicity (pre-natal developmental toxicity)
17/09/2019
17/09/2019
01/11/2019
01/11/2019
Fatty acids, C16-18, barium salts 292-883-6 91002-07-2 Long-term toxicity to fish //Note: testing to be done with barium dichloride (CAS number 10361-37-2) 04/04/2014 19/05/2014
Fatty acids, C12-14, α-sulfo, disodium salts 942-523-5 -
Long-term toxicity to fish (OECD 212 – Registrant’s preference)
Reproductive toxicity (pre-natal developmental toxicity) on rodents
Sub-chronic toxicity (90-day): oral on rodents
25/06/2019
25/06/2019
25/06/2019
09/08/2019
09/08/2019
09/08/2019
Benzyltoluene 248-654-8 27776-01-8 Long-term toxicity to fish (OECD 210) 25/06/2019 09/08/2019
Strontium hydroxide 242-367-1 18480-07-4
Long-term toxicity to fish Note: testing proposed with strontium dinitrate (EC: 233-131-9, CAS: 10042-76-9)
Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with strontium dinitrate (EC: 233-131-9, CAS: 10042-76-9)
Reproductive toxicity (two-generation reproductive toxicity) Note: testing proposed with strontium dinitrate (EC: 233-131-9, CAS: 10042-76-9)
15/04/2014
15/04/2014
15/04/2014
30/05/2014
30/05/2014
30/05/2014
Triethoxyoctylsilane 220-941-2 2943-75-1 Long-term toxicity to fish || Note: testing proposed with Triethoxy(2,4,4-trimethylpentyl)silane (EC 252-558-1) 17/04/2015 04/06/2015
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11-C13 odd-numbered alkyl) derivs. and sodium hydroxide and chloroacetic acid 938-645-3 -
Long-term toxicity to fish Note: testing proposed with [Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11 alkyl) derivs. and sodium hydroxide and chloroacetic acid] (EC 271-794-6)
Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with [Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid] (EC 931-291-0)
Sub-chronic toxicity (90-day): oral Note: testing proposed with [Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid] (EC 931-291-0)
16/03/2015
16/03/2015
16/03/2015
30/04/2015
30/04/2015
30/04/2015
1,3-diphenylguanidine 203-002-1 102-06-7 Long-term toxicity to fish 15/04/2011 30/05/2011
2-Hydroxy-5-nonyl(branched)-benzaldehyde oxime 605-717-8 174333-80-3 Long-term toxicity to fish 22/06/2017 07/08/2017
4,4'-isopropylidenedicyclohexanol 201-244-2 80-04-6 Long-term toxicity to fish 17/06/2014 01/08/2014
6-tert-butyl-2,4-xylenol 217-533-1 1879-09-0 Long-term toxicity to fish 15/07/2014 29/08/2014
Acetic acid, chloro-, sodium salt, reaction products with 4,5-dihydro-2-undecyl-1H-imidazole-1-ethanol and sodium hydroxide 271-794-6 68608-66-2 Long-term toxicity to fish 18/02/2014 04/04/2014
Aziridine 205-793-9 151-56-4 Long-term toxicity to fish 26/01/2011 14/03/2011
Barium carbonate 208-167-3 513-77-9 Long-term toxicity to fish 29/04/2011 14/06/2011
Barium hydroxide 241-234-5 17194-00-2 Long-term toxicity to fish 29/04/2011 14/06/2011
Barium sulfate 231-784-4 7727-43-7 Long-term toxicity to fish 29/04/2011 14/06/2011
Bis(dibutyldithiocarbamato-S,S')copper 237-695-7 13927-71-4 Long-term toxicity to fish 22/06/2017 07/08/2017
Bisdecanoyl peroxide 212-092-1 762-12-9 Long-term toxicity to fish 27/09/2017 13/11/2017
Dibutyl fumarate 203-327-9 105-75-9 Long-term toxicity to fish 16/05/2011 30/06/2011
Fatty acids, C16-18 and C18-unsatd., Et esters 285-206-0 85049-36-1 Long-term toxicity to fish 01/07/2011 15/08/2011
Fatty acids, tall-oil, compds. with oleylamine 288-315-1 85711-55-3 Long-term toxicity to fish 04/04/2014 19/05/2014
Fatty acids, tall-oil, reaction products with acrylic acid 939-424-4 - Long-term toxicity to fish 04/04/2014 19/05/2014



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