Previous Testing Proposals
Previous Testing Proposals
Previous Testing Proposals
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
Triethoxyhexadecylsilane | 240-465-9 | 16415-13-7 |
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Hexadecyltrimethoxysilane (EC 240-464-3) || Note: Testing proposal is based on concern identified by the registrant Sub-chronic toxicity (90-day): oral |
07/07/2020 07/07/2020 |
21/08/2020 21/08/2020 |
Details | |
hexadecyltrimethoxysilane | 240-464-3 | 16415-12-6 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/05/2020 | 09/07/2020 | Details | |
hexadecyltrimethoxysilane | 240-464-3 | 16415-12-6 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/10/2014 16/10/2014 |
01/12/2014 01/12/2014 |
Details | |
hexadecyltrimethoxysilane | 240-464-3 | 16415-12-6 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
25/11/2021 25/11/2021 |
10/01/2022 10/01/2022 |
Details | |
Reaction mass of (2S-cis)-tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-2H-pyran and Tetrahydro-4-methyl-2-(2-methylpropen-1-yl)pyran (2R,4R) and Tetrahydro-4-methyl-2-(2-methylpropen-1-yl)pyran (2S,4S) and (2R-cis)-tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-2H-pyran | 939-429-1 | 16409-43-1 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
30/11/2015 30/11/2015 |
14/01/2016 14/01/2016 |
Details | |
3-(Trimethoxysilyl)propyl (2E,4E)-hexa-2,4-dienoate | 642-902-2 | 163802-53-7 | Genetic toxicity in vivo | 10/03/2017 | 25/04/2017 | Details | |
Strontium carbonate | 216-643-7 | 1633-05-2 | Long-term toxicity to fish | 31/05/2011 | 15/07/2011 | Details | |
Hexamethylene diisocyanate, oligomerisation product, blocked with 3,5-dimethyl-1H-pyrazole | 605-318-9 | 163206-31-3 | Sub-chronic toxicity (90 day): inhalation | 12/12/2014 | 26/01/2015 | Details | |
Phenyl bis(2,4,6-trimethylbenzoyl)-phosphine oxide | 423-340-5 | 162881-26-7 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
22/12/2010 22/12/2010 22/12/2010 |
07/02/2011 07/02/2011 07/02/2011 |
Details | |
Condensation products of dimerised fatty acids, C18-unsaturated, with N,N-dimethyl-1,3-propanediamine and 1,3-propanediamine | 605-296-0 | 162627-17-0 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90 day): oral |
14/08/2014 14/08/2014 14/08/2014 |
28/09/2014 28/09/2014 28/09/2014 |
Details | |
(Z)-N-octadec-9-enylhexadecan-1-amide | 240-367-6 | 16260-09-6 | Reproductive toxicity (pre-natal developmental toxicity) | 14/08/2014 | 28/09/2014 | Details | |
Tris(2,5,8,11-tetraoxatridecyl) orthoborate | 310-290-3 | 161907-80-8 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
15/09/2011 15/09/2011 15/09/2011 |
31/10/2011 31/10/2011 31/10/2011 |
Details | |
2,2-dimethyl-3-oxopropyl acetate | 811-188-6 | 16184-79-5 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. | 01/09/2017 | 16/10/2017 | Details | |
Bis(2-ethylhexyl) peroxydicarbonate | 240-282-4 | 16111-62-9 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/04/2014 15/04/2014 |
30/05/2014 30/05/2014 |
Details | |
Hexafluoropropene, oxidized, oligomers, reduced, fluorinated | 500-537-5 | 161075-00-9 | Bioaccumulation aquatic / sediment | 16/10/2014 | 01/12/2014 | Details | |
1,6-bis(2,3-epoxypropoxy)hexane | 240-260-4 | 16096-31-4 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): dermal |
15/03/2011 15/03/2011 15/03/2011 |
29/04/2011 29/04/2011 29/04/2011 |
Details | |
1,6-bis(2,3-epoxypropoxy)hexane | 240-260-4 | 16096-31-4 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): dermal |
15/09/2011 15/09/2011 15/09/2011 |
31/10/2011 31/10/2011 31/10/2011 |
Details | |
Fatty acids, tall oil, oligomeric reaction products with maleic anhydride and rosin, calcium magnesium zinc salts, consisting of mainly calcium, magnesium, zinc salts of maleated rosin, fatty acids and rosin | 500-451-8 | 160901-14-4 |
Reproductive toxicity (pre-natal developmental toxicity) //Note: to be tested with Rosin, maleated (CAS RN 8050-28-0) Reproductive toxicity (two-generation reproductive toxicity) //Note: Testing proposed with Rosin, Fumarated (CAS RN 65997-04-7) Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin, fumarated (CAS RN 65997-04-7) and Rosin, maleated (CAS RN 8050-28-0) |
02/07/2013 02/07/2013 02/07/2013 |
16/08/2013 16/08/2013 16/08/2013 |
Details | |
Fatty acids, tall-oil, oligomeric reaction products with maleic anhydride and rosin, calcium magnesium zinc salts | 500-451-8 | 160901-14-4 | Reproductive toxicity (pre-natal developmental toxicity) | 06/03/2012 | 20/04/2012 | Details | |
4,4,7,7-tetraethoxy-3,8-dioxa-4,7-disiladecane | 240-212-2 | 16068-37-4 |
Genetic toxicity in vivo
|| Note: Testing proposal is based on concern identified by the registrant Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
17/06/2020 17/06/2020 17/06/2020 17/06/2020 |
03/08/2020 03/08/2020 03/08/2020 03/08/2020 |
Details | |
1-hydroxy-4-[[4-[(methylsulphonyl)oxy]phenyl]amino]anthraquinone | 216-475-4 | 1594-08-7 | Genetic toxicity in vivo | 01/07/2021 | 16/08/2021 | Details | |
Triammonium hydrogen ethylenediaminetetraacetate | 240-073-8 | 15934-01-7 | Sub-chronic toxicity (90 day): inhalation | 16/06/2011 | 01/08/2011 | Details | |
A mixture of: bis[4-diphenylsulfoniumphenyl]sulfide-bishexafluoroantimonate; thiophenoxyphenylsulfonium hexafluoroantimonate | 403-500-0 | 159120-95-3 | Genetic toxicity in vivo | 03/10/2023 | 17/11/2023 | Details | |
Propylidynetrimethanol, ethoxylated, esters with acrylic acid, reaction products with diethylamine | 500-425-6 | 159034-91-0 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
26/08/2021 26/08/2021 |
11/10/2021 11/10/2021 |
Details | |
Propylidynetrimethanol, ethoxylated, esters with acrylic acid, reaction products with diethylamine | 500-425-6 | 159034-91-0 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | 16/12/2020 | 01/02/2021 | Details | |
2,2-bis[[(1-oxopentyl)oxy]methyl]propane-1,3-diyl divalerate | 239-937-7 | 15834-04-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 21/10/2019 | 05/12/2019 | Details | |
Fatty acids, C16-C18 and C18-unsatd., ME esters, epoxidized | 605-143-8 | 158318-67-3 | Reproductive toxicity (pre-natal developmental toxicity) | 16/05/2014 | 30/06/2014 | Details | |
Tri(isopropyl)silyl acrylate | 457-670-6 | 157859-20-6 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
31/08/2015 31/08/2015 |
15/10/2015 15/10/2015 |
Details | |
Tri(isopropyl)silyl acrylate | 457-670-6 | 157859-20-6 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
31/08/2015 31/08/2015 |
15/10/2015 15/10/2015 |
Details | |
sodium cumenesulphonate | 239-854-6 | 15763-76-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 16/12/2016 | 30/01/2017 | Details | |
Sodium p-cumenesulphonate | 239-854-6 | 15763-76-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Sodium (xylenes and 4-ethylbenzene) sulphonate Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with sodium cumene sulphonate |
22/06/2017 22/06/2017 |
07/08/2017 07/08/2017 |
Details | |
sodium p-cumenesulphonate | 239-854-6 | 15763-76-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Sodium xylene sulphonate | 24/04/2015 | 12/06/2015 | Details | |
Alcohols, C16-18 and C18-unsatd., ethoxylated, sulfates, sodium salts | 500-345-1 | 157627-95-7 | Reproductive toxicity (pre-natal developmental toxicity) | 30/06/2023 | 14/08/2023 | Details | |
Disodium; 4-Amino-3-{4-[4-(2,4-diamino-phenylazo)-benzenesulfonylamino]-phenylazo}-5-hydroxy-6-phenylazo-naphthalene-2,7-disulfonate | 605-104-5 | 157577-99-6 | Genetic toxicity in vivo | 26/08/2021 | 11/10/2021 | Details | |
bis(4-(1,1,3,3-tetramethylbutyl)phenyl)amine | 239-816-9 | 15721-78-5 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
18/02/2014 18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 04/04/2014 |
Details | |
1,4-Benzenedicarboxylic acid, mixed Bu and 2-ethylhexyl diesters | 946-149-3 | 1571954-81-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
21/05/2018 21/05/2018 |
05/07/2018 05/07/2018 |
Details | |
[1R-(1α,2β,5α)]-1-(isopropyl)-2-methoxy-4-methylcyclohexane | 216-365-6 | 1565-76-0 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | 19/10/2020 | 03/12/2020 | Details | |
2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3-propanediyl diacrylate; 2,2-bis(acryloyloxymethyl)butyl acrylate; trimethylolpropane triacrylate | 239-701-3 | 15625-89-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Sub-chronic toxicity (90-day): oral |
25/05/2020 25/05/2020 |
09/07/2020 09/07/2020 |
Details | |
2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3-propanediyl diacrylate; 2,2-bis(acryloyloxymethyl)butyl acrylate; trimethylolpropane triacrylate | 239-701-3 | 15625-89-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 26/10/2022 | 12/12/2022 | Details | |
Cobalt(2+) propionate | 216-333-1 | 1560-69-6 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/09/2011 02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 17/10/2011 |
Details | |
Calcium cyanamide | 205-861-8 | 156-62-7 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 28/02/2018 | 16/04/2018 | Details | |
calcium cyanamide | 205-861-8 | 156-62-7 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
15/04/2011 15/04/2011 |
30/05/2011 30/05/2011 |
Details | |
2,2'-azobis[4-methoxy-2,4-dimethylvaleronitrile] | 239-593-8 | 15545-97-8 | Genetic toxicity in vivo | 17/06/2020 | 03/08/2020 | Details | |
Diphosphoric acid, compound with 1,3,5-triazine-2,4,6-triamine | 239-590-1 | 15541-60-3 | Reproductive toxicity (pre-natal developmental toxicity) | 26/08/2021 | 11/10/2021 | Details | |
bis(4-tert-butylcyclohexyl) peroxydicarbonate | 239-557-1 | 15520-11-3 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/07/2014 15/07/2014 |
29/08/2014 29/08/2014 |
Details | |
2,2'-(octylimino)bisethanol | 239-555-0 | 15520-05-5 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
25/11/2019 25/11/2019 |
09/01/2020 09/01/2020 |
Details | |
3-(trimethoxysilyl)propyl isocyanate | 239-415-9 | 15396-00-6 |
Genetic toxicity in vivo Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: it is proposed to use the information from an ongoing study with 3-(trimethoxysilyl)propylamine (EC 237-511-5) |
30/09/2021 30/09/2021 |
15/11/2021 15/11/2021 |
Details | |
Copper(I, II) sulfite | 884-197-6 | 15293-86-4 | 7.6.2 Genetic toxicity in vivo||Note: testing proposed with copper(I,II) sulfite dihydrate (CAS No. 13814-81-8) | 08/03/2024 | 22/04/2024 | Details | |
(chloromethyl)triethoxysilane | 239-311-3 | 15267-95-5 | Genetic toxicity in vivo | 16/10/2014 | 01/12/2014 | Details | |
sodium 1H-benzotriazolide | 239-269-6 | 15217-42-2 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 1H-Benzotriazole (EC 202-394-1) | 16/12/2016 | 30/01/2017 | Details | |