Previous Testing Proposals

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

Showing 301 - 350 of 1,996 results.

Name	EC Number	CAS Number	Hazard endpoint for which vertebrate testing was proposed	Date of publication to call for available information	Deadline for submitting information
2-chloropropane	200-858-8	75-29-6	Reproductive toxicity (extended one-generation reproductive toxicity study)	26/03/2018	11/05/2018	Details
2-dibutylaminoethanol	203-057-1	102-81-8	Genetic toxicity in vivo	21/03/2014	05/05/2014	Details
2-ethoxyethyl-2-(4-(2,6-dihydro-2,6-dioxo-7-phenyl-1,5-dioxaindacen-3-yl)phenoxy)acetate	403-960-2	-	Genetic toxicity in vivo	03/10/2023	17/11/2023	Details
2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3-propanediyl diacrylate; 2,2-bis(acryloyloxymethyl)butyl acrylate; trimethylolpropane triacrylate	239-701-3	15625-89-5	Reproductive toxicity (extended one-generation reproductive toxicity study)	26/10/2022	12/12/2022	Details
2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3-propanediyl diacrylate; 2,2-bis(acryloyloxymethyl)butyl acrylate; trimethylolpropane triacrylate	239-701-3	15625-89-5	Reproductive toxicity (extended one-generation reproductive toxicity study) Sub-chronic toxicity (90-day): oral	25/05/2020 25/05/2020	09/07/2020 09/07/2020	Details
2-ethyl-2-[[(1-oxononyl)oxy]methyl]propane-1,3-diyl dinonan-1-oate	204-793-6	126-57-8	Long-term toxicity to fish \|\| Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates	17/04/2015	04/06/2015	Details
2-ethyl-4-methylimidazole	213-234-5	931-36-2	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/04/2014 15/04/2014	30/05/2014 30/05/2014	Details
2-ethyl-N,N-bis(2-ethylhexyl)hexylamine	217-461-0	-	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/01/2012 16/01/2012	01/03/2012 01/03/2012	Details
2-ethylaminoethanol	203-797-5	110-73-6	Sub-chronic toxicity (90-day): oral	18/02/2014	04/04/2014	Details
2-ethylanthraquinone	201-535-4	84-51-5	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity)	18/02/2014 18/02/2014	04/04/2014 04/04/2014	Details
2-ethylhexanoic acid, monoester with propane-1,2-diol	285-503-5	85114-00-7	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	03/03/2014 03/03/2014	17/04/2014 17/04/2014	Details
2-ethylhexyl 10-ethyl-4,4-dimethyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate	260-829-0	57583-35-4	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity Sub-chronic toxicity (90-day): oral	01/09/2016 01/09/2016 01/09/2016	17/10/2016 17/10/2016 17/10/2016	Details
2-ethylhexyl 10-ethyl-4,4-dimethyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate	260-829-0	57583-35-4	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	27/01/2020 27/01/2020 27/01/2020	12/03/2020 12/03/2020 12/03/2020	Details
2-ethylhexyl 10-ethyl-4-[[2-[(2-ethylhexyl)oxy]-2-oxoethyl]thio]-4-octyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate	248-227-6	27107-89-7	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/05/2011 16/05/2011 16/05/2011	30/06/2011 30/06/2011 30/06/2011	Details
2-ethylhexyl 10-ethyl-4-[[2-[(2-ethylhexyl)oxy]-2-oxoethyl]thio]-4-octyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate	248-227-6	27107-89-7	Genetic toxicity in vivo	30/11/2015	14/01/2016	Details
2-ethylhexyl acrylate	203-080-7	103-11-7	Long-term toxicity to fish	03/10/2023	17/11/2023	Details
2-ethylhexyl benzoate	226-641-8	5444-75-7	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	02/06/2014 02/06/2014 02/06/2014	17/07/2014 17/07/2014 17/07/2014	Details
2-ethylhexyl nitrate	248-363-6	27247-96-7	Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90 day): inhalation	29/04/2011 29/04/2011 29/04/2011	14/06/2011 14/06/2011 14/06/2011	Details
2-Hexyldecan-1-ol	219-370-1	2425-77-6	Reproductive toxicity (two-generation reproductive toxicity)	05/04/2011	20/05/2011	Details
2-hydroxy-2-methylpropiophenone	231-272-0	7473-98-5	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90 day)	21/10/2019 15/03/2011 15/03/2011 15/03/2011	05/12/2019 29/04/2011 29/04/2011 29/04/2011	Details
2-hydroxy-3-propyl-2H-furan-5-one	821-451-7	78920-10-2	Genetic toxicity in vivo \|\| Note: Testing proposal is based on concern identified by the registrant. \|\|	25/11/2019	09/01/2020	Details
2-Hydroxy-5-nonyl(branched)-benzaldehyde oxime	605-717-8	174333-80-3	Long-term toxicity to fish	22/06/2017	07/08/2017	Details
2-imidazolidone	204-436-4	120-93-4	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/04/2014 15/04/2014	30/05/2014 30/05/2014	Details
2-isocyanatoethyl methacrylate	250-284-7	30674-80-7	Reproductive toxicity (pre-natal developmental toxicity)	23/03/2020	07/05/2020	Details
2-mercaptoethanol	200-464-6	60-24-2	Reproductive toxicity (pre-natal developmental toxicity)	15/04/2011	30/05/2011	Details
2-methoxyethyl acrylate	221-499-3	3121-61-7	Genetic toxicity in vivo	21/03/2014	05/05/2014	Details
2-methyl-1,3-propanediol	412-350-5	2163-42-0	Long-term toxicity to fish	15/01/2024	29/02/2024	Details
2-methylbut-3-yn-2-ol	204-070-5	115-19-5	Sub-chronic toxicity (90-day): oral	20/04/2015	08/06/2015	Details
2-methylpentane-2,4-diol	203-489-0	107-41-5	Reproductive toxicity (two-generation reproductive toxicity)	16/06/2011	01/08/2011	Details
2-methylpentane-2,4-diol	203-489-0	107-41-5	Long-term toxicity to fish	01/04/2022	16/05/2022	Details
2-methylpentane-2,4-diol	203-489-0	107-41-5	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	26/03/2018 26/03/2018	11/05/2018 11/05/2018	Details
2-methylpropan-1-ol	201-148-0	78-83-1	Long-term toxicity to fish \|\|Note: testing proposed with Propan-1-ol (EC no. 200-746-9) \|\|Note: testing proposed with Pentan-1-ol (EC no. 200-752-1)	26/10/2022	12/12/2022	Details
2-methylpropane-2-thiol	200-890-2	75-66-1	Reproductive toxicity (extended one-generation reproductive toxicity study)\|\|Note: testing proposed with tert-dodecanethiol (EC no. 246-619-1 ) Reproductive toxicity (pre-natal developmental toxicity)\|\|Note: testing proposed with tert-dodecanethiol (EC no. 246-619-1)	22/09/2022 22/09/2022	07/11/2022 07/11/2022	Details
2-methylpropene	204-066-3	115-11-7	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): inhalation	06/06/2023 06/06/2023 06/06/2023	21/07/2023 21/07/2023 21/07/2023	Details
2-methylpropene	204-066-3	115-11-7	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: substance belongs to a category and testing is proposed with the Substance (EC 204-066-3) and Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: substance belongs to a category and testing is proposed with the Substance (EC 204-066-3) and Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1) Sub-chronic toxicity (90 day): inhalation \|\| Note: substance belongs to a category and testing is proposed with Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1)	16/12/2020 16/12/2020 16/12/2020	01/02/2021 01/02/2021 01/02/2021	Details
2-Naphthalenol, 1-[[4-(phenylazo)phenyl]azo]-, ar-heptyl ar',ar''-Me derivs.	296-120-8	92257-31-3	Genetic toxicity in vivo	16/12/2020	01/02/2021	Details
2-Octyldodecan-1-ol	226-242-9	5333-42-6	Reproductive toxicity (two-generation reproductive toxicity)	05/04/2011	20/05/2011	Details
2-Oxepanone, polymer with 1,4-butanediol	608-670-1	31831-53-5	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/05/2014 16/05/2014	30/06/2014 30/06/2014	Details
2-Oxepanone, polymer with 1,6-hexanediol	609-271-5	36609-29-7	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with 2-Oxepanone, polymer with 1,4-butanediol Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with 2-Oxepanone, polymer with 1,4-butanediol	16/10/2014 16/10/2014	01/12/2014 01/12/2014	Details
2-Oxepanone, polymer with 2-ethyl-2-(hydroxymethyl)-1,3-propanediol	500-099-5	37625-56-2	Reproductive toxicity (pre-natal developmental toxicity)	15/07/2011	29/08/2011	Details
2-Oxetanone, 3-C12-16-alkyl-4-C13-17-alkylidene derivs., (4E)-	939-401-9	1469983-41-2	Long-term toxicity to fish \|\|Note: testing proposed with 2-Oxetanone, 3-C14-16-alkyl 4-C15-17-alkylidene derivs (EC no. 308-760-8)	15/07/2022	29/08/2022	Details
2-Oxetanone, 3-C14-16-alkyl 4-C15-17-alkylidene derivs.	308-760-8	98246-87-8	Long-term toxicity to fish	22/09/2022	07/11/2022	Details
2-phenoxyethyl acrylate	256-360-6	48145-04-6	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/04/2014 15/04/2014	30/05/2014 30/05/2014	Details
2-phenylethanol	200-456-2	60-12-8	Reproductive toxicity (two-generation reproductive toxicity)	15/04/2014	30/05/2014	Details
2-phosphonobutane-1,2,4-tricarboxylic acid	253-733-5	37971-36-1	Long-term toxicity to fish\|\|Note: testing proposed with Tetrasodium hydrogen 2-phosphonatobutane-1,2,4-tricarbolxyate, (EC No. 266-442-3) Reproductive toxicity (pre-natal developmental toxicity)\|\|Note: testing proposed with Tetrasodium hydrogen 2-phosphonatobutane-1,2,4-tricarbolxyate, (EC No. 266-442-3)	26/10/2022 26/10/2022	12/12/2022 12/12/2022	Details
2-piperazin-1-ylethylamine	205-411-0	140-31-8	Sub-chronic toxicity (90-day): oral	21/10/2011	05/12/2011	Details
2-piperazin-1-ylethylamine	205-411-0	140-31-8	Reproductive toxicity (extended one-generation reproductive toxicity study)	01/09/2017	16/10/2017	Details
2-piperazin-1-ylethylamine	205-411-0	140-31-8	Chronic toxicity/carcinogenicity Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity)	14/02/2011 14/02/2011 14/02/2011	31/03/2011 31/03/2011 31/03/2011	Details
2-Propanol, 1,1'-[[3-[(3-aminopropyl)amino]propyl]imino]bis-, N-tallow alkyl derivs	307-276-4	97592-79-5	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/08/2011 16/08/2011	30/09/2011 30/09/2011	Details
2-Propenoic acid, (1-methyl-1,2-ethanediyl) bis[oxy(methyl-2,1-ethanediyl)] ester, reaction products with diethylamine	601-101-8	111497-86-0	Reproductive toxicity (pre-natal developmental toxicity)	02/06/2014	17/07/2014	Details

Showing 301 - 350 of 1,996 results.

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