Previous Testing Proposals

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

Showing 301 - 400 of 1,996 results.

Name	EC Number	CAS Number	Hazard endpoint for which vertebrate testing was proposed	Date of publication to call for available information	Deadline for submitting information
3,6,9,12-tetraoxotridecanol	245-883-5	23783-42-8	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC 203-962-1)	21/10/2021	07/12/2021	Details
Carboxylic acids, di-, C4-6	271-678-5	68603-87-2	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with adipic acid (EC 204-673-3)	21/10/2021	07/12/2021	Details
Decanal	203-957-4	112-31-2	Reproductive toxicity (pre-natal developmental toxicity)	21/10/2021	07/12/2021	Details
Disodium [2,4-dihydro-4-[(2-hydroxy-5-nitrophenyl)azo]-5-methyl-2-phenyl-3H-pyrazol-3-onato(2-)][3-hydroxy-4-[(2-hydroxy-1-naphthyl)azo]-7-nitronaphthalene-1-sulphonato(3-)]chromate(2-)	274-490-1	70236-60-1	Genetic toxicity in vivo	21/10/2021	07/12/2021	Details
n-methyl-n-[c18-(unsaturated)alkanoyl]glycine	701-177-3	-	Reproductive toxicity (extended one-generation reproductive toxicity study)	21/10/2021	07/12/2021	Details
N-Phenyl-diethanolamine, reaction products with formaldehyde	942-131-4	-	Reproductive toxicity (pre-natal developmental toxicity)	21/10/2021	07/12/2021	Details
Polysulfides, bis[3-(triethoxysilyl)propyl]	915-673-4	-	Sub-chronic toxicity (90-day): oral	21/10/2021	07/12/2021	Details
Propanamide, 2-hydroxy-N,N-dimethyl-	609-066-0	35123-06-9	Reproductive toxicity (extended one-generation reproductive toxicity study)	21/10/2021	07/12/2021	Details
Fatty acids, C12-14 (even numbered), methyl ester	629-776-4	308065-15-8	Sub-chronic toxicity (90-day): oral Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	30/09/2021 30/09/2021 30/09/2021	15/11/2021 15/11/2021 15/11/2021	Details
n4,n4'-hexane-1,6-diylbis[n-butyl-6-chloro-n,n'-bis(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,5-triazine-2,4-diamine]	835-183-3	83420-16-0	Bioaccumulation aquatic / sediment Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	30/09/2021 30/09/2021 30/09/2021	15/11/2021 15/11/2021 15/11/2021	Details
Tetrakis(phenylmethyl)thioperoxydi(carbothioamide)	404-310-0	10591-85-2	Long-term toxicity to fish Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	30/09/2021 30/09/2021 30/09/2021	15/11/2021 15/11/2021 15/11/2021	Details
3-(trimethoxysilyl)propyl isocyanate	239-415-9	15396-00-6	Genetic toxicity in vivo Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: it is proposed to use the information from an ongoing study with 3-(trimethoxysilyl)propylamine (EC 237-511-5)	30/09/2021 30/09/2021	15/11/2021 15/11/2021	Details
Ethylene	200-815-3	74-85-1	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	30/09/2021 30/09/2021	15/11/2021 15/11/2021	Details
Saccharomyces cerevisiae, lysate	305-230-8	94350-12-6	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	30/09/2021 30/09/2021	15/11/2021 15/11/2021	Details
1,1'-(methylenedi-p-phenylene)bismaleimide	237-163-4	13676-54-5	Reproductive toxicity (pre-natal developmental toxicity)	30/09/2021	15/11/2021	Details
3-methoxy-3-methylbutan-1-ol	260-252-4	56539-66-3	Reproductive toxicity (extended one-generation reproductive toxicity study)	30/09/2021	15/11/2021	Details
A mixture of: esters of C14-C15 branched alcohols with 3,5-di-t-butyl-4-hydroxyphenyl propionic acid; C15 branched and linear alkyl 3,5-bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoate; C13 branched and linear alkyl 3,5-bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoate	413-750-2	-	Reproductive toxicity (pre-natal developmental toxicity)	30/09/2021	15/11/2021	Details
benzenesulfonic acid, 4-c10-13-alkyl derivs.-, salts with amines, c16-c18 (even numbered) alkyl	953-378-2	-	Long-term toxicity to fish	30/09/2021	15/11/2021	Details
BICYCLO[3.1.1]HEPT-2-ENE,2,6,6-TRIMETHYL-,POLYMER WITH 6,6-DIMETHYL-2-METHYLENEBICYCLO[3.1.1]HEPTANE	608-613-0	-	Reproductive toxicity (pre-natal developmental toxicity)	30/09/2021	15/11/2021	Details
Dodecanoic acid, 2,2-dimethyl-3-oxopropyl ester	468-880-2	102985-93-3	Long-term toxicity to fish	30/09/2021	15/11/2021	Details
Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) (101-68-8), Octylamine (111-86-4) and Cyclohexylamine (108-91-8)	926-119-6	-	Long-term toxicity to fish \|\| Note: testing proposed with Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl (EC 905-837-3) and Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) (CAS: 101-68-8), Octylamine (111-86-4) and Hexamethylenediamine (124-09-4) (EC no 924-670-7)	30/09/2021	15/11/2021	Details
Sodium 2,4,5-trichlorobenzenesulphonate	258-548-3	53423-65-7	Genetic toxicity in vivo	30/09/2021	15/11/2021	Details
Alkane 6	438-390-3	-	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with 1-Dodecene, dimer, hydrogenated (EC 604-768-3) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) Reproductive toxicity (extended one-generation reproductive toxicity study \|\| Note: testing proposed with Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1), 1-decene, dimer (EC 917-709-4) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with 1-Dodecene, Dimer (EC 814-509-8), 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) and Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1)	26/08/2021 26/08/2021 26/08/2021	11/10/2021 11/10/2021 11/10/2021	Details
Branched hexatriacontane	417-070-7	-	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with 1-Dodecene, dimer, hydrogenated (EC 604-768-3) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1), 1-decene, dimer (EC 917-709-4), 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9), 1-Dodecene, Dimer (EC 814-509-8 ), Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1)	26/08/2021 26/08/2021 26/08/2021	11/10/2021 11/10/2021 11/10/2021	Details
N,N-dimethyl-N'-(2,2,6,6-tetramethylpiperidin-4-yl)propane-1,3-diamine	278-817-9	78014-16-1	Sub-chronic toxicity (90-day): oral Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021 26/08/2021 26/08/2021	11/10/2021 11/10/2021 11/10/2021	Details
(1-methylethylidene)di-4,1-phenylenetetraphenyl diphosphate	425-220-8	5945-33-5	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021 26/08/2021	11/10/2021 11/10/2021	Details
3-chloropropyltrimethoxysilane	219-787-9	2530-87-2	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021 26/08/2021	11/10/2021 11/10/2021	Details
6,8-Dioxabicyclo[3.2.1]octan-4-one, (1S,5R) (Cyrene)	807-130-4	53716-82-8	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021 26/08/2021	11/10/2021 11/10/2021	Details
N-(2-ethylhexyl)isononan-1-amide	810-288-7	1700656-13-8	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021 26/08/2021	11/10/2021 11/10/2021	Details
Peracetic acid	201-186-8	79-21-0	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021 26/08/2021	11/10/2021 11/10/2021	Details
Propylidynetrimethanol, ethoxylated, esters with acrylic acid, reaction products with diethylamine	500-425-6	159034-91-0	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	26/08/2021 26/08/2021	11/10/2021 11/10/2021	Details
1-Dodecanamine, reaction products with 1,1'-methylenebis[4-isocyanatobenzene] and 1-octanamine	812-490-0	1312943-21-7	Long-term toxicity to fish \|\| Note: testing proposed with Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl (EC no. 905-837-3) and Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) (Octylamine and Hexamethylenediamine (EC no. 924-670-7)	26/08/2021	11/10/2021	Details
1-Octadecanamine, reaction products with 1,1'-methylenebis[4-isocyanatobenzene] and 1-octanamine	812-491-6	1312943-23-9	Long-term toxicity to fish \|\| Note: testing proposed with Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl (EC no. 905-837-3) and Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) , Octylamine) and Hexamethylenediamine (EC no. 924-670-7)	26/08/2021	11/10/2021	Details
2,5-Furandione, dihydro-, mono-C15-20-alkenyl derivs.	272-221-2	68784-12-3	Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021	11/10/2021	Details
2,6-dimethyloct-7-en-2-ol	242-362-4	18479-58-8	Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021	11/10/2021	Details
2-[2,2-bis(2-prop-2-enoyloxyethoxymethyl)butoxy]ethyl 3-(dibutylamino)propanoate	701-363-4	-	Sub-chronic toxicity (90-day): oral	26/08/2021	11/10/2021	Details
3-(isodecyloxy)propylammonium acetate	249-166-8	28701-67-9	Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021	11/10/2021	Details
6-(cyclohexylamino)-3-methyl-3H-dibenz[f,ij]isoquinoline-2,7-dione	244-320-0	21295-57-8	Genetic toxicity in vivo	26/08/2021	11/10/2021	Details
Diphosphoric acid, compound with 1,3,5-triazine-2,4,6-triamine	239-590-1	15541-60-3	Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021	11/10/2021	Details
Disodium; 4-Amino-3-{4-[4-(2,4-diamino-phenylazo)-benzenesulfonylamino]-phenylazo}-5-hydroxy-6-phenylazo-naphthalene-2,7-disulfonate	605-104-5	157577-99-6	Genetic toxicity in vivo	26/08/2021	11/10/2021	Details
Hydrocarbons, C18-C22, n-alkanes, n-alkenes (Waksol A)	953-917-1	-	Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021	11/10/2021	Details
Linseed oil, oxidized	272-038-8	68649-95-6	Genetic toxicity in vivo	26/08/2021	11/10/2021	Details
Manganese carbonate	209-942-9	598-62-9	Reproductive toxicity (pre-natal developmental toxicity)	26/08/2021	11/10/2021	Details
N-Phenyl-diethanolamine, reaction products with formaldehyde	942-131-4	-	Genetic toxicity in vivo	26/08/2021	11/10/2021	Details
Phenol, 2-methoxy-, reaction products with 2,2-dimethyl-3-methylenebicyclo[2.2.1]heptane, hydrogenated	275-062-7	70955-71-4	Reproductive toxicity (extended one-generation reproductive toxicity study)	26/08/2021	11/10/2021	Details
platinum(IV) nitrate/nitric acid solution	432-400-1	-	Genetic toxicity in vivo	26/08/2021	11/10/2021	Details
Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl	905-837-3	-	Long-term toxicity to fish \|\| Note: substance forms part of category; testing is also proposed with Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI), Octylamine and Hexamethylenediamine (EC no. 923-615-4)	26/08/2021	11/10/2021	Details
Reaction mass of dipotassium 3,3'-sulphonylbis(benzenesulphonate) and potassium 3-(phenylsulphonyl)benzenesulphonate	915-932-1	-	Genetic toxicity in vivo	26/08/2021	11/10/2021	Details
1-Dodecene, dimer with 1-decene, hydrogenated	604-766-2	151006-58-5	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) and 1-Dodecene, dimer, hydrogenated (EC 604-768-3) Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1), 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) and 1-decene, dimer (EC 917-709-4) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1), 1-Dodecene, Dimer (EC 814-509-8) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9)	01/07/2021 01/07/2021 01/07/2021	16/08/2021 16/08/2021 16/08/2021	Details
A mixture of isomers of branched tetracosane	417-060-2	151006-61-0	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) and 1-Dodecene, dimer, hydrogenated (EC 604-768-3) Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 1-decene, dimer (EC 917-709-4), Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9), 1-Dodecene, Dimer (EC 814-509-8 ) and Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1)	01/07/2021 01/07/2021 01/07/2021	16/08/2021 16/08/2021 16/08/2021	Details
1,1'-(isopropylidene)bis[3,5-dibromo-4-(2,3-dibromo-2-methylpropoxy)benzene]	306-832-3	97416-84-7	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	01/07/2021 01/07/2021	16/08/2021 16/08/2021	Details
1-hydroxy-4-[[4-[(methylsulphonyl)oxy]phenyl]amino]anthraquinone	216-475-4	1594-08-7	Genetic toxicity in vivo	01/07/2021	16/08/2021	Details
2,2'-ethylenedioxydiethyl bis(2-ethylhexanoate)	202-319-2	94-28-0	Reproductive toxicity (pre-natal developmental toxicity)	01/07/2021	16/08/2021	Details
2,4,6-tri-tert-butylphenol	211-989-5	732-26-3	Reproductive toxicity (pre-natal developmental toxicity)	01/07/2021	16/08/2021	Details
Bis[2-[2-(1-methylethyl)-3-oxazolidinyl]ethyl] hexan-1,2-diylbiscarbamate	261-879-6	59719-67-4	Genetic toxicity in vivo	01/07/2021	16/08/2021	Details
Cyclohexyldimethylamine	202-715-5	98-94-2	Reproductive toxicity (pre-natal developmental toxicity)	01/07/2021	16/08/2021	Details
Disodium 4-amino-3,6-bis[[4-[(2,4-diaminophenyl)azo]phenyl]azo]-5-hydroxynaphthalene-2,7-disulphonate	229-208-1	6428-31-5	Genetic toxicity in vivo	01/07/2021	16/08/2021	Details
Inorganic phosphorus salt	428-310-5	-	Reproductive toxicity (pre-natal developmental toxicity)	01/07/2021	16/08/2021	Details
Linalool	201-134-4	78-70-6	Reproductive toxicity (pre-natal developmental toxicity)	01/07/2021	16/08/2021	Details
Pentaerythritol tetrakis(3-mercaptopropionate)	231-472-8	7575-23-7	Long-term toxicity to fish	01/07/2021	16/08/2021	Details
Reaction mass of trisodium [μ-[4-[[3,3'-dihydroxy-4'-[(2-hydroxy-6-sulpho-1-naphthyl)azo][1,1'-biphenyl]-4-yl]azo]-3-hydroxynaphthalene-2,7-disulphonato(7-)]]dicuprate(3-) and triammonium [μ-[4-[[3,3'-dihydroxy-4'-[(2-hydroxy-6-sulpho-1-naphthyl)azo][1,1'-biphenyl]-4-yl]azo]-3-hydroxynaphthalene-2,7-disulphonato(7-)]]dicuprate(3-)	945-577-8	-	Sub-chronic toxicity (90-day): oral	01/07/2021	16/08/2021	Details
Tris(nitrato-O)nitrosylruthenium	252-068-8	34513-98-9	Genetic toxicity in vivo	01/07/2021	16/08/2021	Details
Vinylene carbonate	212-825-5	872-36-6	Sub-chronic toxicity (90-day): oral Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity)	20/05/2021 20/05/2021 20/05/2021	05/07/2021 05/07/2021 05/07/2021	Details
N-pentan-2-ylidenehydroxylamine	484-470-6	623-40-5	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	20/05/2021 20/05/2021	05/07/2021 05/07/2021	Details
undec-10-enoic acid	203-965-8	112-38-9	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	20/05/2021 20/05/2021	05/07/2021 05/07/2021	Details
Condensation products of phenol and salicylaldehyde	947-320-5	-	Genetic toxicity in vivo	20/05/2021	05/07/2021	Details
Iron, complexes with diazotized 5-amino-2-(phenylamino)benzenesulfonic acid monosodium salt coupled with 4-[(2-hydroxy-3,5-dinitrophenyl)azo]-1,3-benzenediol, diazotized 4-nitrobenzenamine and diazotized 3-aminobenzenesulfonic acid monosodium salt	276-464-5	72207-77-3	Genetic toxicity in vivo \|\| Note: testing proposed with Acid Brown 360 (EC 946-788-8)	20/05/2021	05/07/2021	Details
N-(4-amino-9,10-dihydro-3-methoxy-9,10-dioxo-1-anthryl)-4-methylbenzenesulphonamide	201-369-2	81-68-5	Genetic toxicity in vivo	20/05/2021	05/07/2021	Details
Potassium hexadecyl hydrogen phosphate	242-768-1	19035-79-1	Reproductive toxicity (pre-natal developmental toxicity)	20/05/2021	05/07/2021	Details
(octahydro-4,7-methano-1H-indenediyl)bis(methylene) diacrylate	255-901-3	42594-17-2	Long-term toxicity to fish Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	22/04/2021 22/04/2021 22/04/2021	07/06/2021 07/06/2021 07/06/2021	Details
Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction	270-728-3	68477-39-4	Sub-chronic toxicity (90-day): oral \|\| Note: The substance belongs to a category (“Low Benzene Naphthas”). Testing is proposed with this substance and with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: The substance belongs to a category (“Low Benzene Naphthas”). Testing is proposed with this substance and with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: The substance belongs to a category (“Low Benzene Naphthas”). Testing is proposed with this substance and with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7)	22/04/2021 22/04/2021 22/04/2021	07/06/2021 07/06/2021 07/06/2021	Details
Extracts (petroleum), heavy naphtha solvent	265-099-7	64741-98-6	Sub-chronic toxicity (90-day): oral \|\| Note: This substance belongs to a category (“Low Benzene Naphthas”). Testing proposed with this substance and with Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3) Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: This substance belongs to a category (“Low Benzene Naphthas”). Testing proposed with this substance and with Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: This substance belongs to a category (“Low Benzene Naphthas”). Testing proposed with this substance and with Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3)	22/04/2021 22/04/2021 22/04/2021	07/06/2021 07/06/2021 07/06/2021	Details
Naphtha (petroleum), steam-cracked middle arom.	271-138-9	68516-20-1	Sub-chronic toxicity (90-day): oral \|\| Note: This substance belongs to a category. Testing proposed with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) and Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3) Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: This substance belongs to a category. Testing proposed with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) and Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: This substance belongs to a category. Testing proposed with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) and Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3)	22/04/2021 22/04/2021 22/04/2021	07/06/2021 07/06/2021 07/06/2021	Details
Solvent naphtha (petroleum), heavy arom.	265-198-5	64742-94-5	Sub-chronic toxicity (90-day): oral \|\| Note: This substance belongs to a category (“Low Benzene Naphthas”). Testing proposed with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) and Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3) Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: This substance belongs to a category (“Low Benzene Naphthas”). Testing proposed with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) and Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: This substance belongs to a category (“Low Benzene Naphthas”). Testing proposed with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) and Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3)	22/04/2021 22/04/2021 22/04/2021	07/06/2021 07/06/2021 07/06/2021	Details
1,1,1,2,2,4,5,5,5-nonafluoro-4-(trifluoromethyl )-3-pentanone	436-710-6	756-13-8	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	22/04/2021 22/04/2021	07/06/2021 07/06/2021	Details
Sodium hydrogen-5-sulphoisophthalate	228-845-2	6362-79-4	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	22/04/2021 22/04/2021	07/06/2021 07/06/2021	Details
1,8-naphthylenediamine	207-529-8	479-27-6	Genetic toxicity in vivo	22/04/2021	07/06/2021	Details
2,2'-[(1-methylethylidene)bis(cyclohexane-4,1-diyloxymethylene)]bisoxirane	236-502-3	13410-58-7	Genetic toxicity in vivo	22/04/2021	07/06/2021	Details
7-amino-3,8-bis-[4-(2-sulfoxyethylsulfonyl)-2-sulfophenylazo]-4-hydroxynaphthalene-2-sulfonic acid, Na/K salt; 7-amino-3-[4-(2-sulfoxyethylsulfonyl)phenylazo]-4-hydroxy-8-[4-(2-sulfoxyethylsulfonyl)-2-sulfophenylazo]naphthalene-2-sulfonic acid, Na/K salt; 7-amino-8-[4-(2-sulfoxyethylsulfonyl)-phenylazo]-4-hydroxy-3-[4-(2-sulfoxyethylsulfonyl)-2-sulfophenylazo]naphthalene-2-sulfonic acid, Na/K salt; reaction mass of: 7-amino-3,8-bis-[4-(2-sulfoxyethylsulfonyl)phenylazo]-4-hydroxynaphthalene-2-sulfonic acid, Na/K salt	429-070-4	-	Sub-chronic toxicity (90-day): oral	22/04/2021	07/06/2021	Details
benzenesulfonic acid, mono- and dialkylation products with c16-20 (even numbered, branched and linear) olefins, calcium salts, calcium carbonate, overbased, including distillates (petroleum), hydrotreated, solvent-refined, solvent-dewaxed, or catalytic dewaxed, light or heavy paraffinic c15-c50	701-356-6	-	Long-term toxicity to fish	22/04/2021	07/06/2021	Details
Bis(O,O-diisopropyl dithiophosphate)bis(cyclohexylamine) zinc	809-986-4	52585-16-7	Genetic toxicity in vivo	22/04/2021	07/06/2021	Details
Butane-1,4-diol	203-786-5	110-63-4	Reproductive toxicity (extended one-generation reproductive toxicity study)	22/04/2021	07/06/2021	Details
N-[4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl]-2-methyl-prop-2-enamide	611-915-5	59941-98-9	Genetic toxicity in vivo	22/04/2021	07/06/2021	Details
o-xylene	202-422-2	95-47-6	Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with p-xylene (EC 203-396-5)	22/04/2021	07/06/2021	Details
Reaction products of C18 (unsaturated) fatty acids and dimethyl sulfate and triethanolamine	931-216-1	-	Long-term toxicity to fish \|\| Note: testing proposed with Fatty acids, C16-18 (even numbered) and C18 unsatd., reaction products with diethylene triamine, di-Me sulfate quaternized (EC 937-237-2)	22/04/2021	07/06/2021	Details
Star anise, Illicium verum, ext.	283-518-1	84650-59-9	Genetic toxicity in vivo	22/04/2021	07/06/2021	Details
1-Dodecene, dimers	814-509-8	62132-67-6	Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with 1-Decene trimer, hydrogenated and tetramers (EC 614-695-9) and 1-Dodecene, dimer, hydrogenated (EC 604-768-3) Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with 1-decene, homopolymer, hydrogenated (EC 500-183-1), 1-Decene trimer, hydrogenated and tetramers (EC 614-695-9) and 1-decene, dimer, unhydrogenated (EC 917-709-4) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with the Substance, 1-decene, homopolymer, hydrogenated (EC 500-183-1), and 1-Decene trimer, hydrogenated and tetramers (EC 614-695-9)	18/03/2021 18/03/2021 18/03/2021	03/05/2021 03/05/2021 03/05/2021	Details
3-aminopropyltriethoxysilane	213-048-4	919-30-2	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	18/03/2021 18/03/2021	03/05/2021 03/05/2021	Details
N,N'-bis(3-aminopropyl)ethylenediamine	234-147-9	10563-26-5	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	18/03/2021 18/03/2021	03/05/2021 03/05/2021	Details
Phthalic anhydride	201-607-5	85-44-9	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	18/03/2021 18/03/2021	03/05/2021 03/05/2021	Details
Reaction products of n-octanol and acrylic acid, first distillation pitch	938-925-5	-	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	18/03/2021 18/03/2021	03/05/2021 03/05/2021	Details
S-(3-(triethoxysilyl)propyl)octanethioate	436-690-9	220727-26-4	Reproductive toxicity (extended one-generation reproductive toxicity study Reproductive toxicity (pre-natal developmental toxicity)	18/03/2021 18/03/2021	03/05/2021 03/05/2021	Details
(E)-N-(pentan-2-ylidene)hydroxylamine	484-470-6	623-40-5	Reproductive toxicity (pre-natal developmental toxicity)	18/03/2021	03/05/2021	Details
1,2-Ethanediamine, N-(2-aminoethyl)-, reaction products with glycidyl tolyl ether	282-199-6	84144-79-6	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: Testing proposal is based on concern identified by the registrant.	18/03/2021	03/05/2021	Details
1,3-diphenyl-2-thiourea	203-004-2	102-08-9	Genetic toxicity in vivo	18/03/2021	03/05/2021	Details
1-imino-1H-isoindol-3-amine	222-426-8	3468-11-9	Genetic toxicity in vivo	18/03/2021	03/05/2021	Details
2-tert-butyl-1,4-dimethoxybenzene	244-216-5	21112-37-8	Genetic toxicity in vivo	18/03/2021	03/05/2021	Details
[3-(2,3-epoxypropoxy)propyl]triethoxysilane	220-011-6	2602-34-8	Genetic toxicity in vivo	18/03/2021	03/05/2021	Details
Bis(2,4,4-trimethylpentyl)phosphinic acid	280-445-7	83411-71-6	Sub-chronic toxicity (90-day): oral	18/03/2021	03/05/2021	Details
Disodium 1-amino-4-[[4-[(2-bromo-1-oxoallyl)amino]-2-sulphonatophenyl]amino]-9,10-dihydro-9,10-dioxoanthracene-2-sulphonate	274-397-6	70209-99-3	Genetic toxicity in vivo	18/03/2021	03/05/2021	Details

Showing 301 - 400 of 1,996 results.

Export in: