Previous Testing Proposals

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

Showing 401 - 500 of 2,011 results.

Name	EC Number	CAS Number	Hazard endpoint for which vertebrate testing was proposed	Date of publication to call for available information	Deadline for submitting information
1,3-diphenylguanidine	203-002-1	102-06-7	Long-term toxicity to fish	15/04/2011	30/05/2011	Details
1,5-Diisocyanatopentane	807-040-5	4538-42-5	Long-term toxicity to fish	30/06/2023	14/08/2023	Details
11-aminoundecanoic acid	219-417-6	2432-99-7	Long-term toxicity to fish	03/10/2023	17/11/2023	Details
2,2'-[oxybis(methylene)]-bis[2-ethylpropane-1,3-diol]	245-509-0	23235-61-2	Long-term toxicity to fish	15/01/2024	29/02/2024	Details
2,2'-isopropylidenebis(p-phenyleneoxy)diethanol	212-985-6	901-44-0	Long-term toxicity to fish	22/09/2022	07/11/2022	Details
2,6-dimethyloct-7-en-2-ol	242-362-4	18479-58-8	Long-term toxicity to fish	03/10/2023	17/11/2023	Details
2-ethylhexyl acrylate	203-080-7	103-11-7	Long-term toxicity to fish	03/10/2023	17/11/2023	Details
2-Hydroxy-5-nonyl(branched)-benzaldehyde oxime	605-717-8	174333-80-3	Long-term toxicity to fish	22/06/2017	07/08/2017	Details
2-methyl-1,3-propanediol	412-350-5	2163-42-0	Long-term toxicity to fish	15/01/2024	29/02/2024	Details
2-methylpentane-2,4-diol	203-489-0	107-41-5	Long-term toxicity to fish	01/04/2022	16/05/2022	Details
2-Oxetanone, 3-C14-16-alkyl 4-C15-17-alkylidene derivs.	308-760-8	98246-87-8	Long-term toxicity to fish	22/09/2022	07/11/2022	Details
3-ethyloxetane-3-methanol	221-254-0	3047-32-3	Long-term toxicity to fish	03/10/2023	17/11/2023	Details
3-methoxy-3-methylbutan-1-ol	260-252-4	56539-66-3	Long-term toxicity to fish	26/10/2022	12/12/2022	Details
3-methylpentane-1,5-diol	224-709-1	4457-71-0	Long-term toxicity to fish	01/03/2023	17/04/2023	Details
4,4'-isopropylidenedicyclohexanol	201-244-2	80-04-6	Long-term toxicity to fish	17/06/2014	01/08/2014	Details
4,4'-sulphonyldiphenol	201-250-5	80-09-1	Long-term toxicity to fish	16/06/2022	01/08/2022	Details
4,8-Dimethyl-2,5,7,10-tetraoxaundecane	813-999-0	59039-15-5	Long-term toxicity to fish	30/06/2023	14/08/2023	Details
4-methylpentan-2-one	203-550-1	108-10-1	Long-term toxicity to fish	06/06/2023	21/07/2023	Details
5,5'-dithiodi-1,3,4-thiadiazole-2(3H)-thione	276-763-0	72676-55-2	Long-term toxicity to fish	30/06/2023	14/08/2023	Details
6-tert-butyl-2,4-xylenol	217-533-1	1879-09-0	Long-term toxicity to fish	15/07/2014	29/08/2014	Details
[3aR-(3aα,5aβ,9aα,9bβ)]-dodecahydro-3a,6,6,9a-tetramethylnaphtho[2,1-b]furan	229-861-2	6790-58-5	Long-term toxicity to fish	22/09/2022	07/11/2022	Details
Acetic acid, chloro-, sodium salt, reaction products with 4,5-dihydro-2-undecyl-1H-imidazole-1-ethanol and sodium hydroxide	271-794-6	68608-66-2	Long-term toxicity to fish	18/02/2014	04/04/2014	Details
Androst-4-ene-3,17-dione	200-554-5	63-05-8	Long-term toxicity to fish	21/01/2021	08/03/2021	Details
Aziridine	205-793-9	151-56-4	Long-term toxicity to fish	26/01/2011	14/03/2011	Details
Barium carbonate	208-167-3	513-77-9	Long-term toxicity to fish	29/04/2011	14/06/2011	Details
Barium hydroxide	241-234-5	17194-00-2	Long-term toxicity to fish	29/04/2011	14/06/2011	Details
Barium sulfate	231-784-4	7727-43-7	Long-term toxicity to fish	29/04/2011	14/06/2011	Details
benzenesulfonic acid, 4-c10-13-alkyl derivs.-, salts with amines, c16-c18 (even numbered) alkyl	953-378-2	-	Long-term toxicity to fish	30/09/2021	15/11/2021	Details
benzenesulfonic acid, mono- and dialkylation products with c16-20 (even numbered, branched and linear) olefins, calcium salts, calcium carbonate, overbased, including distillates (petroleum), hydrotreated, solvent-refined, solvent-dewaxed, or catalytic dewaxed, light or heavy paraffinic c15-c50	701-356-6	-	Long-term toxicity to fish	22/04/2021	07/06/2021	Details
Benzyldimethylamine	203-149-1	103-83-3	Long-term toxicity to fish	06/06/2023	21/07/2023	Details
Bis(dibutyldithiocarbamato-S,S')copper	237-695-7	13927-71-4	Long-term toxicity to fish	22/06/2017	07/08/2017	Details
Bisdecanoyl peroxide	212-092-1	762-12-9	Long-term toxicity to fish	27/09/2017	13/11/2017	Details
Carboxymethyldimethyl-3-[[(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)sulphonyl]amino]propylammonium hydroxide	252-046-8	34455-29-3	Long-term toxicity to fish	03/10/2023	17/11/2023	Details
Di-tert-butyl trisulphide	224-226-6	4253-90-1	Long-term toxicity to fish	30/06/2023	14/08/2023	Details
Dibutyl fumarate	203-327-9	105-75-9	Long-term toxicity to fish	16/05/2011	30/06/2011	Details
Dibutyl hydrogen phosphate	203-509-8	107-66-4	Long-term toxicity to fish	10/05/2022	27/06/2022	Details
Diethylmethylbenzenediamine	270-877-4	68479-98-1	Long-term toxicity to fish	04/12/2023	18/01/2024	Details
Dodecanoic acid, 2,2-dimethyl-3-oxopropyl ester	468-880-2	102985-93-3	Long-term toxicity to fish	30/09/2021	15/11/2021	Details
Esterification products of fatty acids, C18 (unsaturated) alkyl and adipic acid with pentaerythritol	952-795-7	-	Long-term toxicity to fish	03/11/2023	18/12/2023	Details
Fatty acids, C16-18 and C18-unsatd., Et esters	285-206-0	85049-36-1	Long-term toxicity to fish	01/07/2011	15/08/2011	Details
Fatty acids, C18-unsatd., reaction products with diethylenetriamine	629-715-1	1226892-43-8	Long-term toxicity to fish	26/10/2022	12/12/2022	Details
Fatty acids, tall-oil, compds. with N-[3-(dimethylamino)propyl]tall-oil amides	295-714-4	92128-22-8	Long-term toxicity to fish	03/10/2023	17/11/2023	Details
Fatty acids, tall-oil, compds. with oleylamine	288-315-1	85711-55-3	Long-term toxicity to fish	04/04/2014	19/05/2014	Details
Fatty acids, tall-oil, reaction products with acrylic acid	939-424-4	-	Long-term toxicity to fish	04/04/2014	19/05/2014	Details
Heptanoic acid	203-838-7	111-14-8	Long-term toxicity to fish	31/01/2023	17/03/2023	Details
Hexyl 2-(1-(diethylaminohydroxyphenyl)methanoyl)benzoate	443-860-6	302776-68-7	Long-term toxicity to fish	16/08/2011	30/09/2011	Details
Imidazolidine-2-thione	202-506-9	96-45-7	Long-term toxicity to fish	29/04/2011	14/06/2011	Details
Isononanoic acid, C16-18 (even numbered)-alkyl esters	601-141-6	111937-03-2	Long-term toxicity to fish	01/04/2022	16/05/2022	Details
Mercaptoacetic acid	200-677-4	68-11-1	Long-term toxicity to fish	31/01/2023	17/03/2023	Details
methyl acrylate; methyl propenoate	202-500-6	96-33-3	Long-term toxicity to fish	03/10/2023	17/11/2023	Details
Multi-Wall Carbon Nanotubes, synthetic graphite in tubular shape	231-955-3	7782-42-5	Long-term toxicity to fish	03/11/2011	19/12/2011	Details
N,N-dimethyldecan-1-amide	238-405-1	14433-76-2	Long-term toxicity to fish	15/07/2011	29/08/2011	Details
N-(2-nitrophenyl)phosphoric triamide	477-690-9	-	Long-term toxicity to fish	18/03/2021	03/05/2021	Details
N-butyl phenyl ether	214-426-1	1126-79-0	Long-term toxicity to fish	03/04/2023	22/05/2023	Details
Naphthenic acids	215-662-8	1338-24-5	Long-term toxicity to fish	01/07/2011	15/08/2011	Details
Oxydipropyl dibenzoate	248-258-5	27138-31-4	Long-term toxicity to fish	10/08/2018	24/09/2018	Details
p-cresol	203-398-6	106-44-5	Long-term toxicity to fish	10/05/2022	27/06/2022	Details
Pentaerythritol	204-104-9	115-77-5	Long-term toxicity to fish	03/05/2023	19/06/2023	Details
Pentaerythritol tetrakis(3-mercaptopropionate)	231-472-8	7575-23-7	Long-term toxicity to fish	01/07/2021	16/08/2021	Details
Polyamide wax	434-430-9	-	Long-term toxicity to fish	07/07/2020	21/08/2020	Details
potassium titanium oxide (K2Ti6O13)	432-240-0	12056-51-8	Long-term toxicity to fish	17/05/2017	03/07/2017	Details
Prop-2-yn-1-ol	203-471-2	107-19-7	Long-term toxicity to fish	22/09/2022	07/11/2022	Details
Reaction mass of 1,3-dioxane-5,5-dimethanol and 1,3-Propanediol, 2-(hydroxymethyl)-2-[(methoxymethoxy)methyl]-	911-819-6	-	Long-term toxicity to fish	31/01/2023	17/03/2023	Details
Reaction mass of 2-ethyl-2-(methoxymethyl)-propane-1,3-diol and 2-ethylpropane-1,3-diol	938-572-7	-	Long-term toxicity to fish	22/09/2022	07/11/2022	Details
Reaction mass of ethoxylated (= 3 moles) bisphenol A dimethacrylate and (1-methylethylidene)bis(4,1-phenyleneoxy-2,1-ethanediyl) bismethacrylate	939-702-5	-	Long-term toxicity to fish	25/11/2019	09/01/2020	Details
reaction products of 1,4-butanediol with 1,3-chloro-2,3-epoxypropane, esters with prop-2-enoic acid	701-230-0	-	Long-term toxicity to fish	10/05/2022	27/06/2022	Details
Reaction products of n-octanol and acrylic acid, first distillation pitch	938-925-5	-	Long-term toxicity to fish	15/01/2024	29/02/2024	Details
Reaction products of tetrazotized 5-amino-2-[(E)-2-(4-amino-2-sulfophenyl)ethenyl]benzenesulfonic acid with 6-amino-4-hydroxynaphthalene-2-sulfonic acid and 4-amino-5-hydroxynaphthalene-2,7-disulfonic acid in 2-[bis(2-hydroxyethyl)amino]ethanol	916-899-6	-	Long-term toxicity to fish	25/11/2021	10/01/2022	Details
Silsesquioxanes, phenyl	-	70131-69-0	Long-term toxicity to fish	18/09/2014	03/11/2014	Details
Strontium carbonate	216-643-7	1633-05-2	Long-term toxicity to fish	31/05/2011	15/07/2011	Details
Strontium chromate	232-142-6	7789-06-2	Long-term toxicity to fish	31/05/2011	15/07/2011	Details
Styrene	202-851-5	100-42-5	Long-term toxicity to fish	30/06/2023	14/08/2023	Details
Styrene	202-851-5	100-42-5	Long-term toxicity to fish	04/09/2023	19/10/2023	Details
SUMILIZER GP	442-450-4	-	Long-term toxicity to fish	25/11/2021	10/01/2022	Details
tert-butyl perbenzoate	210-382-2	614-45-9	Long-term toxicity to fish	23/03/2020	07/05/2020	Details
tert-dodecanethiol	246-619-1	25103-58-6	Long-term toxicity to fish	16/06/2022	01/08/2022	Details
Tetramethylammonium hydroxide	200-882-9	75-59-2	Long-term toxicity to fish	30/06/2023	14/08/2023	Details
Tetrasodium hydrogen 2-phosphonatobutane-1,2,4-tricarboxylate	266-442-3	66669-53-2	Long-term toxicity to fish	22/09/2022	07/11/2022	Details
trimethoxy(2,4,4-trimethylpentyl)silane	251-995-5	34396-03-7	Long-term toxicity to fish	26/10/2022	12/12/2022	Details
Trimethylolpropane and its reaction products with methyloxirane	957-630-2	-	Long-term toxicity to fish	15/01/2024	29/02/2024	Details
Triphenylphosphine	210-036-0	603-35-0	Long-term toxicity to fish	03/10/2023	17/11/2023	Details
undec-10-enoic acid	203-965-8	112-38-9	Long-term toxicity to fish	16/10/2014	01/12/2014	Details
Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl	905-837-3	-	Long-term toxicity to fish \|\| Note: substance forms part of category; testing is also proposed with Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI), Octylamine and Hexamethylenediamine (EC no. 923-615-4)	26/08/2021	11/10/2021	Details
Reaction products of C18 (unsaturated) fatty acids and dimethyl sulfate and triethanolamine	931-216-1	-	Long-term toxicity to fish \|\| Note: testing proposed with Fatty acids, C16-18 (even numbered) and C18 unsatd., reaction products with diethylene triamine, di-Me sulfate quaternized (EC 937-237-2)	22/04/2021	07/06/2021	Details
Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) (101-68-8), Octylamine (111-86-4) and Cyclohexylamine (108-91-8)	926-119-6	-	Long-term toxicity to fish \|\| Note: testing proposed with Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl (EC 905-837-3) and Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) (CAS: 101-68-8), Octylamine (111-86-4) and Hexamethylenediamine (124-09-4) (EC no 924-670-7)	30/09/2021	15/11/2021	Details
1-Dodecanamine, reaction products with 1,1'-methylenebis[4-isocyanatobenzene] and 1-octanamine	812-490-0	1312943-21-7	Long-term toxicity to fish \|\| Note: testing proposed with Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl (EC no. 905-837-3) and Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) (Octylamine and Hexamethylenediamine (EC no. 924-670-7)	26/08/2021	11/10/2021	Details
1-Octadecanamine, reaction products with 1,1'-methylenebis[4-isocyanatobenzene] and 1-octanamine	812-491-6	1312943-23-9	Long-term toxicity to fish \|\| Note: testing proposed with Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl (EC no. 905-837-3) and Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) , Octylamine) and Hexamethylenediamine (EC no. 924-670-7)	26/08/2021	11/10/2021	Details
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11-C13 odd-numbered alkyl) derivs. and sodium hydroxide and chloroacetic acid	938-645-3	-	Long-term toxicity to fish Note: testing proposed with [Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11 alkyl) derivs. and sodium hydroxide and chloroacetic acid] (EC 271-794-6) Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with [Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid] (EC 931-291-0) Sub-chronic toxicity (90-day): oral Note: testing proposed with [Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid] (EC 931-291-0)	16/03/2015 16/03/2015 16/03/2015	30/04/2015 30/04/2015 30/04/2015	Details
Reaction mass of 2,4,6,8,10-pentamethyl-2,4,6,8,10-pentavinylcyclopentasiloxane and 2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane	911-381-6	-	Long-term toxicity to fish \|\| Note: testing proposed with 2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane (EC 219-863-1) \|\| Note: Testing proposal is based on concern identified by the registrant	17/06/2020	03/08/2020	Details
Triethoxyoctylsilane	220-941-2	2943-75-1	Long-term toxicity to fish \|\| Note: testing proposed with Triethoxy(2,4,4-trimethylpentyl)silane (EC 252-558-1)	17/04/2015	04/06/2015	Details
2-methylpropan-1-ol	201-148-0	78-83-1	Long-term toxicity to fish \|\|Note: testing proposed with Propan-1-ol (EC no. 200-746-9) \|\|Note: testing proposed with Pentan-1-ol (EC no. 200-752-1)	26/10/2022	12/12/2022	Details
Strontium hydroxide	242-367-1	18480-07-4	Long-term toxicity to fish Note: testing proposed with strontium dinitrate (EC: 233-131-9, CAS: 10042-76-9) Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with strontium dinitrate (EC: 233-131-9, CAS: 10042-76-9) Reproductive toxicity (two-generation reproductive toxicity) Note: testing proposed with strontium dinitrate (EC: 233-131-9, CAS: 10042-76-9)	15/04/2014 15/04/2014 15/04/2014	30/05/2014 30/05/2014 30/05/2014	Details
Benzyltoluene	248-654-8	27776-01-8	Long-term toxicity to fish (OECD 210)	25/06/2019	09/08/2019	Details
Fatty acids, C12-14, α-sulfo, disodium salts	942-523-5	-	Long-term toxicity to fish (OECD 212 – Registrant’s preference) Reproductive toxicity (pre-natal developmental toxicity) on rodents Sub-chronic toxicity (90-day): oral on rodents	25/06/2019 25/06/2019 25/06/2019	09/08/2019 09/08/2019 09/08/2019	Details
Fatty acids, C16-18, barium salts	292-883-6	91002-07-2	Long-term toxicity to fish //Note: testing to be done with barium dichloride (CAS number 10361-37-2)	04/04/2014	19/05/2014	Details
2,4,7,9-tetramethyl-4,7-decanediol	451-160-7	17913-76-7	Long-term toxicity to fish "\|\| Note: testing proposed with 2,4,7,9-tetramethyldec-5-yne-4,7-diol (EC 204-809-1, CAS 126-86-3) Reproductive toxicity (pre-natal developmental toxicity)	17/09/2019 17/09/2019	01/11/2019 01/11/2019	Details
Acetic acid, chloro-, sodium salt, reaction products with 4,5-dihydro-2-undecyl-1H-imidazole-1-ethanol and sodium hydroxide	271-794-6	68608-66-2	Long-term toxicity to fish Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with Reaction products of 1H-Imidazole- 1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid (EC 931-291-0) Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid (EC 931-291-0	29/02/2016	14/04/2016	Details
benzyl butyl cis-cyclohexane-1,2-dicarboxylate	701-279-8	1931129-39-3	Long-term toxicity to fish \|\| Note: Link to the registration dossier not given as the dossier not yet disseminated. \|\| Note: this substance was previously registered, identified and disseminated with EC No. 810-685-5 Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: Link to registration dossier not given as the dossier not yet disseminated. \|\| Note: this substance was previously registered, identified and disseminated with EC No. 810-685-5 Sub-chronic toxicity (90-day): oral \|\| Note: Link to registration dossier not given as the dossier not yet disseminated. \|\| Note: this substance was previously registered, identified and disseminated with EC No. 810-685-5	10/12/2018 10/12/2018 10/12/2018	24/01/2019 24/01/2019 24/01/2019	Details
1,1,4,4-tetramethylbutane-1,4-diyl bis(2-ethylperoxyhexanoate)	235-935-5	13052-09-0	Long-term toxicity to fish \|\| Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates	12/12/2014	26/01/2015	Details
2-ethyl-2-[[(1-oxononyl)oxy]methyl]propane-1,3-diyl dinonan-1-oate	204-793-6	126-57-8	Long-term toxicity to fish \|\| Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates	17/04/2015	04/06/2015	Details

Showing 401 - 500 of 2,011 results.

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